Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Manuela Bruckner"'
Autor:
Leonhard X. Heinz, Christoph L. Baumann, Marielle S. Köberlin, Berend Snijder, Riem Gawish, Guanghou Shui, Omar Sharif, Irene M. Aspalter, André C. Müller, Richard K. Kandasamy, Florian P. Breitwieser, Andreas Pichlmair, Manuela Bruckner, Manuele Rebsamen, Stephan Blüml, Thomas Karonitsch, Astrid Fauster, Jacques Colinge, Keiryn L. Bennett, Sylvia Knapp, Markus R. Wenk, Giulio Superti-Furga
Publikováno v:
Cell Reports, Vol 11, Iss 12, Pp 1919-1928 (2015)
Lipid metabolism and receptor-mediated signaling are highly intertwined processes that cooperate to fulfill cellular functions and safeguard cellular homeostasis. Activation of Toll-like receptors (TLRs) leads to a complex cellular response, orchestr
Externí odkaz:
https://doaj.org/article/c15f42b992bc40058500731b1ade155b
Autor:
Adrián César-Razquin, Manuele Rebsamen, Manuela Bruckner, Leonhard X. Heinz, Katrin Hörmann, Giulio Superti-Furga, Justyna Konecka, Astrid Fauster, Stefania Scorzoni, Fiorella Schischlik, Katharina L. Willmann, Johannes W. Bigenzahn, Enrico Girardi, Kaan Boztug
Publikováno v:
Cell Death and Differentiation
Cell Death & Differentiation
Cell Death & Differentiation
Regulation of cell and tissue homeostasis by programmed cell death is a fundamental process with wide physiological and pathological implications. The advent of scalable somatic cell genetic technologies creates the opportunity to functionally map su
Autor:
Richard Kumaran Kandasamy, Mariana E. G. de Araujo, Leonhard X. Heinz, Taras Stasyk, Johannes W. Bigenzahn, Michele Galluccio, Lorena Pochini, Manuela Bruckner, Astrid Fauster, Przemyslaw A. Filipek, Berend Snijder, Manuele Rebsamen, Cesare Indiveri, Keiryn L. Bennett, Kilian Huber, Giulio Superti-Furga, Stefania Scorzoni, Lukas A. Huber, Elena L. Rudashevskaya, Claudine Kraft
Publikováno v:
Nature
Cell growth and proliferation are tightly linked to nutrient availability. The mechanistic target of rapamycin complex 1 (mTORC1) integrates the presence of growth factors, energy levels, glucose and amino acids to modulate metabolic status and cellu
Autor:
Monika Sabler, Ciara Cleary, Richard Kumaran Kandasamy, Johannes W. Bigenzahn, Manuela Bruckner, Thomas Penz, Giulio Superti-Furga, Adrijana Stefanovic, Berend Snijder, Manuele Rebsamen, Gregory I. Vladimer, Keiryn L. Bennett, Stefania Scorzoni, Jacques Colinge, André C. Müller, Robert Kralovics, Anna Moskovskich
Publikováno v:
npj systems biology and applications
NPJ Systems Biology and Applications
NPJ Systems Biology and Applications
Studying the relationship between virus infection and cellular response is paradigmatic for our understanding of how perturbation changes biological systems. Immune response, in this context is a complex yet evolutionarily adapted and robust cellular
Autor:
Melanie Planyavsky, Sylvia Knapp, Omar Sharif, Christoph Baumann, Keiryn L. Bennett, Florian Grebien, Giulio Superti-Furga, Andreas Pichlmair, Stephan Blüml, Manuela Bruckner, Pawel Pasierbek, Karin Aumayr, Jacques Colinge, Irene M. Aspalter
Publikováno v:
The Journal of Experimental Medicine
CD14 interacts with and is essential for the functions of endosomal TLR7 and TLR9 in mice.
Recognition of pathogens by the innate immune system requires proteins that detect conserved molecular patterns. Nucleic acids are recognized by cytoplasm
Recognition of pathogens by the innate immune system requires proteins that detect conserved molecular patterns. Nucleic acids are recognized by cytoplasm
Autor:
Stephan Blüml, Sylvia Knapp, Leonhard X. Heinz, Guanghou Shui, Florian P. Breitwieser, Berend Snijder, Omar Sharif, Irene M. Aspalter, Manuele Rebsamen, Thomas Karonitsch, Keiryn L. Bennett, Marielle S. Köberlin, Markus R. Wenk, Astrid Fauster, Christoph Baumann, Andreas Pichlmair, Riem Gawish, Jacques Colinge, André C. Müller, Giulio Superti-Furga, Manuela Bruckner, Richard Kumaran Kandasamy
Publikováno v:
Cell Reports
CELL REPORTS
Cell Reports, Elsevier Inc, 2015, 11 (12), pp.1919-1928. ⟨10.1016/j.celrep.2015.05.006⟩
Cell reports
Cell Reports, Vol 11, Iss 12, Pp 1919-1928 (2015)
CELL REPORTS
Cell Reports, Elsevier Inc, 2015, 11 (12), pp.1919-1928. ⟨10.1016/j.celrep.2015.05.006⟩
Cell reports
Cell Reports, Vol 11, Iss 12, Pp 1919-1928 (2015)
Summary Lipid metabolism and receptor-mediated signaling are highly intertwined processes that cooperate to fulfill cellular functions and safeguard cellular homeostasis. Activation of Toll-like receptors (TLRs) leads to a complex cellular response,
Autor:
Stefan Kubicek, Astrid Fauster, Alexey Stukalov, Johannes W. Bigenzahn, Manuela Gridling, Manuele Rebsamen, Stefan Krautwald, Katja Parapatics, Andreas Linkermann, Manuela Bruckner, C-H Lardeau, Keiryn L. Bennett, Kilian Huber, Jacques Colinge, Stefania Scorzoni, Giulio Superti-Furga
Publikováno v:
Cell Death and Disease
Cell Death and Disease, Nature Publishing Group, 2015, 6 (5), pp.e1767-e1767. ⟨10.1038/cddis.2015.130⟩
Cell Death and Disease, 2015, 6 (5), pp.e1767-e1767. ⟨10.1038/cddis.2015.130⟩
Cell Death & Disease
Cell Death and Disease, Nature Publishing Group, 2015, 6 (5), pp.e1767-e1767. ⟨10.1038/cddis.2015.130⟩
Cell Death and Disease, 2015, 6 (5), pp.e1767-e1767. ⟨10.1038/cddis.2015.130⟩
Cell Death & Disease
Necroptosis is a form of regulated necrotic cell death mediated by receptor-interacting serine/threonine-protein kinase 1 (RIPK1) and RIPK3. Necroptotic cell death contributes to the pathophysiology of several disorders involving tissue damage, inclu
Autor:
Giulio Superti-Furga, Tilmann Bürckstümmer, Manuela Bruckner, Georg E. Winter, Manuele Rebsamen
Publikováno v:
Cytokine. 59:534-535
Introduction TNF signaling can result in NF-kB and MAPK activation, apoptosis or necrosis depending on cell type and cell state. Until recently necrosis has been seen as an uncontrolled mode of cell death when compared to the programmed apoptosis. Th