Výsledky vyhledávání - "Manuela Bragardo"

The T cell activation molecule H4 and the CD28-like molecule ICOS are identical

Autor: Valter Redoglia, Charles A. Janeway, Sara Bonissoni, Manuela Bragardo, Rosanna Vaschetto, Caterina Mezzatesta, Donatella Buonfiglio, Umberto Dianzani, Flavia Bottarel, Thea Bensi

Publikováno v: European Journal of Immunology. 30:3463-3467

The recently cloned CD28-like molecule ICOS displays striking similarities with H4, characterized some years ago in the mouse and recently in humans. Both molecules are selectively expressed by activated and germinal center T cells, display similar s

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00dcf7a2cbe454d40c043cd4358a89b5
https://doi.org/10.1002/1521-4141(2000012)30:12<3463::aid-immu3463>3.0.co

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The Cell Death-Inducing Ability of Glycoprotein 120 from Different HIV Strains Correlates with Their Ability to Induce CD4 Lateral Association with CD95 on CD4+ T Cells

Autor: Fabio Malavasi, Manuela Bragardo, Ugo Ramenghi, Sara Bonissoni, Simona DeFranco, Umberto Dianzani, Donatella Buonfiglio, María José Feito, Flavia Bottarel, Thea Bensi

Publikováno v: AIDS Research and Human Retroviruses. 15:1255-1263

CD4 cross-linking by HIV gp120 triggers CD4+ T cell death. Several authors have suggested that this effect is mediated by CD95, but this possibility is debated by other authors. In a previous work, we found by co-capping that gp120(451) and gp120MN,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3bd7d88c73b28d945f900c8b0ef9899
https://doi.org/10.1089/088922299310151

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CD44 signaling through p56lck involves lateral association with CD4 in human CD4+ T cells

Autor: Antonella Tosti, Manuela Bragardo, Umberto Dianzani, Sara Bonissoni, María José Feito, Myriam Casucci, Andrea Velardi, Flavia Bottarel, Loredana Ruggeri, Isabella Volpi

Publikováno v: International Immunology. 11:1085-1092

CD44 is a family of mucin-like membrane proteins generated by alternative splicing of several exons, and participate in T cell adhesion and activation. CD44-mediated signaling involves activation of p56(lck) and leads to ZAP-70 phosphorylation. The a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::001c66475756ba1fb371bc235b113122
https://doi.org/10.1093/intimm/11.7.1085

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gp 120s derived from four syncytium-inducing HIV-1 strains induce different patterns of CD4 association with lymphocyte surface molecules

Autor: Fabio Malavasi, Sara Bonissoni, Flavia Bottarel, Manuela Bragardo, Umberto Dianzani, Donatella Buonfiglio, María José Feito

Publikováno v: International Immunology. 9:1141-1147

This work extends our previous finding that lymphocyte treatment with gp120IIIB specifically induces CD4 association with several surface molecules to other molecules and to three other gp120s from different HIV-1 strains. The ability to induce this

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31bb4a4cf1e486132d8eca347e2966ca
https://doi.org/10.1093/intimm/9.8.1141

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Expansion of T cells expressing low CD4 or CD8 levels in B-cell chronic lymphocytic leukemia: correlation with disease status and neoplastic phenotype

Autor: Mario Boccadoro, Paola Omedè, Manuela Bragardo, D DiFranco, L Mairone, Filippo Marmont, Fulvia Giaretta, Umberto Dianzani, A Fusaro, Valter Redoglia

Publikováno v: Blood. 83:2198-2205

Peripheral blood (PB) T cells from 56 patients with B-cell chronic lymphocytic leukemia (B-CLL) were analyzed by two- and three-color immunofluorescence (IF) to determine the expansion of distinct T-cell subsets and their relationship with the clinic

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::599c01fceff503790c60ede2aac7bc88
https://doi.org/10.1182/blood.v83.8.2198.2198

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Isoform-specific associations of CD45 with accessory molecules in human T lymphocytes

Autor: Umberto Dianzani, Fabio Malavasi, Manuela Bragardo, Charles A. Janeway, Valter Redoglia, Alessandro Pileri, Kim Bottomly

Publikováno v: Scopus-Elsevier

Association of CD45 with surface molecules was investigated in human T lymphocytes by co-capping. CD45 appeared to be associated with the CD3/T cell receptor complex and with CD4 or CD8 molecules in memory, but not in naive T cells, as previously rep

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0506c82a22d9e909fb10bff917bb0a07
https://doi.org/10.1002/eji.1830220212

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Decreased function of Fas in patients displaying delayed progression of HIV-induced immune deficiency

Autor: Irma Dianzani, Sara Bonissoni, Manuela Bragardo, Donatella Buonfiglio, Daniela DiFranco, Roberto Cauda, Maria Rosaria Capobianchi, Caterina Mezzatesta, Flavia Bottarel, Thea Bensi, Claudia Balotta, Umberto Dianzani, M. B. Lucia

Publikováno v: The hematology journal : the official journal of the European Haematology Association. 2(4)

INTRODUCTION In acquired immune deficiency syndrome patients, apoptosis of uninfected lymphocytes may contribute to development of immune deficiency. This process may involve recruitment of Fas by human immunodeficiency virus products. In line with t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::764a7c2b7dd753f0d4d0ed5923698818
https://pubmed.ncbi.nlm.nih.gov/11920253

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Effects of the human CD38 glycoprotein on the early stages of the HIV-1 replication cycle

Autor: Fabio Malavasi, Ferdinando Dianzani, José M. Rojo, Agostino Pugliese, L. Calosso, Umberto Dianzani, Maria Rosaria Capobianchi, Flavia Bottarel, Thea Bensi, María José Feito, Isabella Abbate, Manuela Bragardo, Andrea Savarino

Publikováno v: Scopus-Elsevier

CD38 displays lateral association with the HIV-1 receptor CD4. This association is potentiated by the HIV-1 envelope glycoprotein gp120. The aim of this work was to evaluate the CD38 role in T cell susceptibility to HIV-1 infection. Using laboratory

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99d3e7d21a554598c77aaa7bc9d63dc9
https://pubmed.ncbi.nlm.nih.gov/10593874

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Characterization of a novel human surface molecule selectively expressed by mature thymocytes, activated T cells and subsets of T cell lymphomas

Autor: Antonino Carbone, Gianluca Gaidano, Kaarle Franssila, Manuela Bragardo, Vito L. Burgio, Roberto Cauda, Sara Bonissoni, Simona Zupo, Charles A. Janeway, Henrik Wolff, Donatella Buonfiglio, Valter Redoglia, Umberto Dianzani

Publikováno v: European journal of immunology. 29(9)

We have previously characterized mouse H4 (mH4), a surface glycoprotein recognized by the C398.4A monoclonal antibody. We now show that C398.4A also binds its human putative homolog (hpH4). Both hpH4 and mH4 (1) are selectively expressed by activated

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1715b3b2a436d8cceaf8241940da15b3
https://pubmed.ncbi.nlm.nih.gov/10508261

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Characterization of H4: a mouse T lymphocyte activation molecule functionally associated with the CD3/T cell receptor

Autor: Sara Bonissoni, José M. Rojo, Henrik Wolff, Manuela Bragardo, Umberto Dianzani, Charles A. Janeway, Donatella Buonfiglio, Pilar Portolés, Valter Redoglia

Publikováno v: European journal of immunology. 26(11)

The monoclonal antibody C398.4A was produced by immunizing Armenian hamsters with the mouse T cell clone D10.G4.1. It recognizes a molecule selectively expressed by activated mouse T cells and was named H4. H4 is expressed on the T cell surface about

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::edb354163dc2d035452e2c9122338066
https://pubmed.ncbi.nlm.nih.gov/8921969

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