Zobrazeno 1 - 10
of 180
pro vyhledávání: '"Manuela Aragno"'
Autor:
Gustavo Ferreira Alves, Eleonora Aimaretti, Maria Luísa da Silveira Hahmeyer, Giacomo Einaudi, Elisa Porchietto, Chiara Rubeo, Enrica Marzani, Manuela Aragno, José Eduardo da Silva-Santos, Carlo Cifani, Daniel Fernandes, Massimo Collino
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 178, Iss , Pp 117191- (2024)
Casein kinase II (CK2) has recently emerged as a pivotal mediator in the propagation of inflammation across various diseases. Nevertheless, its role in the pathogenesis of sepsis remains unexplored. Here, we investigated the involvement of CK2 in sep
Externí odkaz:
https://doaj.org/article/e5075996b90f43a2b50eab4f7d691eba
Autor:
Chiara Rubeo, Gjylije Hoti, Magalì Giordano, Chiara Molinar, Manuela Aragno, Beatrice Mantuano, Stefano Comità, Saveria Femminò, Roberta Cavalli, Francesco Trotta, Claudia Penna, Pasquale Pagliaro
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 11, p 5685 (2024)
Gas-loaded nanocarriers (G-LN) show promise in improving heart transplantation (HTx) outcomes. Given their success in reducing cell death during normothermic hypoxia/reoxygenation (H/R) in vitro, we tested their integration into cardioplegic solution
Externí odkaz:
https://doaj.org/article/0d9f1a72e31d477a8e9ccae02442bbbb
Autor:
Eleonora Aimaretti, Elisa Porchietto, Giacomo Mantegazza, Giorgio Gargari, Debora Collotta, Giacomo Einaudi, Gustavo Ferreira Alves, Enrica Marzani, Alessandro Algeri, Federica Dal Bello, Manuela Aragno, Carlo Cifani, Simone Guglielmetti, Raffaella Mastrocola, Massimo Collino
Publikováno v:
Nutrients, Vol 16, Iss 4, p 552 (2024)
Advanced glycation end products (AGEs) exert a key pathogenic role in the development of obesity and insulin resistance. Thanks to its abundance in bioactive compounds, the microalga Arthrospira platensis (spirulina, SP) is proposed as a nutritional
Externí odkaz:
https://doaj.org/article/024113f805304f8a925c97bca3b9d6ce
Autor:
Eleonora Aimaretti, Guglielmina Chimienti, Chiara Rubeo, Rosa Di Lorenzo, Lucia Trisolini, Federica Dal Bello, Atefeh Moradi, Massimo Collino, Angela Maria Serena Lezza, Manuela Aragno, Vito Pesce
Publikováno v:
Nutrients, Vol 15, Iss 23, p 4874 (2023)
Diets with an elevated content of fat, sucrose, or fructose are recognized models of diet-induced metabolic alterations, since they induce metabolic derangements, oxidative stress, and chronic low-grade inflammation associated with local and systemic
Externí odkaz:
https://doaj.org/article/066af9c1189246f58205aeb5842ca27c
Autor:
Gustavo Ferreira Alves, Ian Stoppa, Eleonora Aimaretti, Chiara Monge, Raffaella Mastrocola, Elisa Porchietto, Giacomo Einaudi, Debora Collotta, Ilaria Bertocchi, Elena Boggio, Casimiro Luca Gigliotti, Nausicaa Clemente, Manuela Aragno, Daniel Fernandes, Carlo Cifani, Christoph Thiemermann, Chiara Dianzani, Umberto Dianzani, Massimo Collino
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Inducible T cell co-stimulator (ICOS), an immune checkpoint protein expressed on activated T cells and its unique ligand, ICOSL, which is expressed on antigen-presenting cells and non-hematopoietic cells, have been extensively investigated in the imm
Externí odkaz:
https://doaj.org/article/1c55e496fa97413c9846216878568c2f
Autor:
Kristiaan Wouters, Alessia S. Cento, Katrien H. Gaens, Margee Teunissen, Jean L. J. M. Scheijen, Federica Barutta, Fausto Chiazza, Debora Collotta, Manuela Aragno, Gabriella Gruden, Massimo Collino, Casper G. Schalkwijk, Raffaella Mastrocola
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Abstract Advanced glycation endproducts (AGEs) are involved in several diseases, including NAFLD and NASH. RAGE is the main receptor mediating the pro-inflammatory signalling induced by AGEs. Therefore, targeting of RAGE has been proposed for prevent
Externí odkaz:
https://doaj.org/article/95cedba2ffd84ffbafb3eae79144aabe
Autor:
Gustavo Ferreira Alves, Eleonora Aimaretti, Giacomo Einaudi, Raffaella Mastrocola, Junior Garcia de Oliveira, Debora Collotta, Elisa Porchietto, Manuela Aragno, Carlo Cifani, Regina Sordi, Christoph Thiemermann, Daniel Fernandes, Massimo Collino
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Sepsis and septic shock are associated with high mortality and are considered one of the major public health concerns. The onset of sepsis is known as a hyper-inflammatory state that contributes to organ failure and mortality. Recent findings suggest
Externí odkaz:
https://doaj.org/article/00a5468dfbbd46cb88b9cdde5a58d58c
Autor:
Debora Collotta, William Hull, Raffaella Mastrocola, Fausto Chiazza, Alessia Sofia Cento, Catherine Murphy, Roberta Verta, Gustavo Ferreira Alves, Giulia Gaudioso, Francesca Fava, Magdi Yaqoob, Manuela Aragno, Kieran Tuohy, Christoph Thiemermann, Massimo Collino
Publikováno v:
Molecular Metabolism, Vol 39, Iss , Pp - (2020)
Objective: Recent evidence suggests the substantial pathogenic role of the Janus kinase (JAK)/signal transducer and activator of transcription (STAT) pathway in the development of low-grade chronic inflammatory response, known as “metaflammation,
Externí odkaz:
https://doaj.org/article/0bd346f6d49542e6a6efd0bfa718368a
Autor:
Guglielmina Chimienti, Antonella Orlando, Francesco Russo, Benedetta D’Attoma, Manuela Aragno, Eleonora Aimaretti, Angela Maria Serena Lezza, Vito Pesce
Publikováno v:
Genes, Vol 12, Iss 9, p 1439 (2021)
Nonalcoholic fatty liver disease (NAFLD) is the leading liver chronic disease featuring hepatic steatosis. Mitochondrial β-oxidation participates in the derangement of lipid metabolism at the basis of NAFLD, and mitochondrial oxidative stress contri
Externí odkaz:
https://doaj.org/article/4f1db56846cb4c938128c2ee8a1822d5
Autor:
Gareth S. D. Purvis, Massimo Collino, Rodrigo A. Loiola, Andrea Baragetti, Fausto Chiazza, Martina Brovelli, Madeeha H. Sheikh, Debora Collotta, Alessia Cento, Raffaella Mastrocola, Manuela Aragno, Juan C. Cutrin, Chris Reutelingsperger, Liliana Grigore, Alberico L. Catapano, Magdi M. Yaqoob, Giuseppe Danilo Norata, Egle Solito, Christoph Thiemermann
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Annexin A1 (ANXA1) is an endogenously produced anti-inflammatory protein, which plays an important role in the pathophysiology of diseases associated with chronic inflammation. We demonstrate that patients with type-2 diabetes have increased plasma l
Externí odkaz:
https://doaj.org/article/8d8511484b7344898fd430c8a2912807