Zobrazeno 1 - 10 of 19 pro vyhledávání: '"Manuela Allegra"'
1
Akademický článek
Transformation of spatial representations along hippocampal circuits
Autor: Bérénice Gandit, Lorenzo Posani, Chun-Lei Zhang, Soham Saha, Cantin Ortiz, Manuela Allegra, Christoph Schmidt-Hieber
Publikováno v: iScience, Vol 27, Iss 7, Pp 110361- (2024)
Summary: The hippocampus is thought to provide the brain with a cognitive map of the external world by processing various types of spatial information. To understand how essential spatial variables such as direction, position, and distance are transf
Externí odkaz: https://doaj.org/article/f32c88e22cec42a8ac32017bf3ea0c24
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2
Akademický článek
Clostridioides difficile and neurological disorders: New perspectives
Autor: Manuele Biazzo, Manuela Allegra, Gabriele Deidda
Publikováno v: Frontiers in Neuroscience, Vol 16 (2022)
Despite brain physiological functions or pathological dysfunctions relying on the activity of neuronal/non-neuronal populations, over the last decades a plethora of evidence unraveled the essential contribution of the microbial populations living and
Externí odkaz: https://doaj.org/article/72e3ef1097fd48129ece2e8abdc558c1
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3
Akademický článek
Pharmacological rescue of adult hippocampal neurogenesis in a mouse model of X-linked intellectual disability
Autor: Manuela Allegra, Cristina Spalletti, Beatrice Vignoli, Stefano Azzimondi, Irene Busti, Pierre Billuart, Marco Canossa, Matteo Caleo
Publikováno v: Neurobiology of Disease, Vol 100, Iss , Pp 75-86 (2017)
Oligophrenin-1 (OPHN1) is a Rho GTPase activating protein whose mutations cause X-linked intellectual disability (XLID). How loss of function of Ophn1 affects neuronal development is only partly understood. Here we have exploited adult hippocampal ne
Externí odkaz: https://doaj.org/article/5df4e3672ad2470e9c4688f8fab3c49f
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4
Akademický článek
Visual System Impairment in a Mouse Model of Krabbe Disease: The Twitcher Mouse
Autor: Ilaria Tonazzini, Chiara Cerri, Ambra Del Grosso, Sara Antonini, Manuela Allegra, Matteo Caleo, Marco Cecchini
Publikováno v: Biomolecules, Vol 11, Iss 1, p 7 (2020)
Krabbe disease (KD, or globoid cell leukodystrophy; OMIM #245200) is an inherited neurodegenerative condition belonging to the class of the lysosomal storage disorders. It is caused by genetic alterations in the gene encoding for the enzyme galactosy
Externí odkaz: https://doaj.org/article/5d89c94cdbe648a5bce6ef88818fbab7
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5
Inhibitory control of synaptic signals preceding motor action in mouse frontal cortex
Autor: Chun-Lei Zhang, Cantin Ortiz, Christoph Schmidt-Hieber, Hsin-Lun Kao, Jean-Pierre Changeux, Uwe Maskos, Fani Koukouli, Manuela Allegra
Preparatory activity in the frontal cortex preceding movement onset is thought to represent a neuronal signature of motor planning. However, how excitatory and inhibitory synaptic inputs to frontal neurons are integrated during movement preparation r
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::4af260392d6143bfc6455936fec328d2
https://doi.org/10.1101/2021.07.05.451151
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6
Visual system impairment in a mouse model of Krabbe disease: The twitcher mouse
Autor: Ambra Del Grosso, Ilaria Tonazzini, Marco Cecchini, Matteo Caleo, Chiara Cerri, Sara Antonini, Manuela Allegra
Publikováno v: Biomolecules 11 (2021): 1–12. doi:10.3390/biom11010007
info:cnr-pdr/source/autori:Tonazzini I.; Cerri C.; Grosso A.D.; Antonini S.; Allegra M.; Caleo M.; Cecchini M./titolo:Visual system impairment in a mouse model of Krabbe disease: The twitcher mouse/doi:10.3390%2Fbiom11010007/rivista:Biomolecules/anno:2021/pagina_da:1/pagina_a:12/intervallo_pagine:1–12/volume:11
Biomolecules
Volume 11
Issue 1
Biomolecules, Vol 11, Iss 7, p 7 (2021)
Krabbe disease (KD, or globoid cell leukodystrophy
OMIM #245200) is an inherited neurodegenerative condition belonging to the class of the lysosomal storage disorders. It is caused by genetic alterations in the gene encoding for the enzyme galac
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2be05fa50c9207396f78bcffd99b1bc5
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8
ROCK/PKA inhibition rescues hippocampal hyperexcitability and GABAergic neuron alterations in Oligophrenin-1 Knock-out mouse model of X-linked intellectual disability
Autor: Laura Restani, Matteo Caleo, Chiara Panzi, Irene Busti, Cristina Spalletti, Manuela Allegra, Pierre Billuart
Publikováno v: Journal of Neuroscience
Journal of Neuroscience, Society for Neuroscience, 2020, pp.0462-19. ⟨10.1523/JNEUROSCI.0462-19.2020⟩
J Neurosci
Oligophrenin-1 (Ophn1) encodes a Rho GTPase activating protein whose mutations cause X-linked intellectual disability (XLID) in humans. Loss of function of Ophn1 leads to impairments in the maturation and function of excitatory and inhibitory synapse
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5288c7d3bd0e757faf422d0f39410202
https://www.hal.inserm.fr/inserm-02506604/document
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9
Foxg1 Upregulation Enhances Neocortical Activity
Autor: Moira Pinzan Rossi, Matteo Caleo, Teresa Sorbo, Yuri Bozzi, Antonello Mallamaci, Giovanni Provenzano, Osvaldo Basilio Artimagnella, Manuela Santo, Laura Ballerini, Manuela Allegra, Wendalina Tigani, Rossana Rauti, Francesco Paolo Ulloa Severino
Foxg1 is an ancient transcription factor gene orchestrating a number of neurodevelopmental processes taking place in the rostral brain. In this study, we investigated its impact on neocortical activity. We found that mice overexpressing Foxg1 in neoc
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4246f1390b83cefd6b0d6fd8ba75162b
http://hdl.handle.net/11577/3349727
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10
The hippocampus as a perceptual map: neuronal and behavioral discrimination during memory encoding
Autor: Christoph Schmidt-Hieber, Lorenzo Posani, Manuela Allegra
Posté sur BioRxiv le 8 décembre 2019; The hippocampus is thought to encode similar events as distinct memory representations that are used for behavioral decisions. Where and how this “pattern separation” function is accomplished in the hippoca
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::88de4c4a5ed256d6e5eff2a97a5dfd91
https://doi.org/10.1101/868794
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