Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Manuela, Portoso"'
Autor:
Bernd Schuettengruber, Mythily Ganapathi, Benjamin Leblanc, Manuela Portoso, Rami Jaschek, Bas Tolhuis, Maarten van Lohuizen, Amos Tanay, Giacomo Cavalli
Publikováno v:
PLoS Biology, Vol 7, Iss 1, p e13 (2009)
Polycomb group (PcG) and trithorax group (trxG) proteins are conserved chromatin factors that regulate key developmental genes throughout development. In Drosophila, PcG and trxG factors bind to regulatory DNA elements called PcG and trxG response el
Externí odkaz:
https://doaj.org/article/856b7027a2ea4671a1a81e8d16779dd3
Autor:
Živa Brenčič, Nicolas Servant, Manuela Portoso, Ivaylo Vassilev, Roberta Ragazzini, Audrey Michaud, Raphaël Margueron, Michel Wassef, Arianna Moiani, Bruno Sargueil
Publikováno v:
The EMBO Journal
Long non‐coding RNAs (lncRNAs) play diverse roles in physiological and pathological processes. Several lncRNAs have been suggested to modulate gene expression by guiding chromatin‐modifying complexes to specific sites in the genome. However, besi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1750557da4a29b1f438e435278d31723
http://europepmc.org/articles/PMC5391141
http://europepmc.org/articles/PMC5391141
Autor:
Takeshi Urano, Juri Rappsilber, Isabelle C Kos-Braun, Flavia de Lima Alves, Manuela Portoso, Elizabeth H. Bayne, Alexander Kagansky, Robin C. Allshire, Karl Ekwall
Publikováno v:
Bayne, E, Portoso, M, Kagansky, A, Kos-Braun, I C, Urano, T, Ekwall, K, Alves, F, Rappsilber, J & Allshire, R C 2008, ' Splicing Factors Facilitate RNAi-Directed Silencing in Fission Yeast ', Science, vol. 322, no. 5901, pp. 602-606 . https://doi.org/10.1126/science.1164029
Heterochromatin formation at fission yeast centromeres is directed by RNA interference (RNAi). Noncoding transcripts derived from centromeric repeats are processed into small interfering RNAs (siRNAs) that direct the RNA-induced transcriptional silen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d6d627d197370e5feed0b175f8831069
https://doi.org/10.1126/science.1164029
https://doi.org/10.1126/science.1164029
Autor:
Robin C. Allshire, Juan Mata, Jürg Bähler, Steven L. Sanders, Manuela Portoso, Tony Kouzarides
Publikováno v:
Cell. 119(5):603-614
Histone lysine methylation is a key regulator of gene expression and heterochromatin function, but little is known as to how this modification impinges on other chromatin activities. Here we demonstrate that a previously uncharacterized SET domain pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a103043d4321676a4c3a6c4e6ef79fad
Autor:
Audrey Michaud, Matthieu Caron, Bérangère Lombard, Michel Wassef, Fabienne Burlina, Aurélie Teissandier, Damarys Loew, Nicolas Servant, Neil Justin, Manuela Portoso, Katia Ancelin, Raphaël Margueron, Simão Teixeira da Rocha, Serena Sanulli, Edith Heard, John Offer, Steve J. Gamblin
Publikováno v:
Molecular Cell
Molecular Cell, 2015, 57 (5), pp.769-783. ⟨10.1016/j.molcel.2014.12.020⟩
Molecular Cell, Elsevier, 2015, 57 (5), pp.769-783. ⟨10.1016/j.molcel.2014.12.020⟩
Molecular Cell, 2015, 57 (5), pp.769-783. ⟨10.1016/j.molcel.2014.12.020⟩
Molecular Cell, Elsevier, 2015, 57 (5), pp.769-783. ⟨10.1016/j.molcel.2014.12.020⟩
Summary Polycomb Group (PcG) proteins maintain transcriptional repression throughout development, mostly by regulating chromatin structure. Polycomb Repressive Complex 2 (PRC2), a component of the Polycomb machinery, is responsible for the methylatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c26e3479b98a1554836541091f26bb9
https://hal.science/hal-01110498
https://hal.science/hal-01110498
Autor:
Steven, Zuryn, Arnaud, Ahier, Manuela, Portoso, Esther Redhouse, White, Marie-Charlotte, Morin, Raphaël, Margueron, Sophie, Jarriault
Publikováno v:
Science (New York, N.Y.). 345(6198)
Natural interconversions between distinct somatic cell types have been reported in species as diverse as jellyfish and mice. The efficiency and reproducibility of some reprogramming events represent unexploited avenues in which to probe mechanisms th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::04b18101b50c2a1ea21a8614b642a6f0
https://pubmed.ncbi.nlm.nih.gov/25268170
https://pubmed.ncbi.nlm.nih.gov/25268170
Autor:
Raphaël Margueron, Arnaud Ahier, Steven Zuryn, Esther Redhouse White, Manuela Portoso, Sophie Jarriault, Marie-Charlotte Morin
Publikováno v:
Science
Science, AAAS, 2014, ⟨10.1126/science.1255885⟩
Science, AAAS, 2014, ⟨10.1126/science.1255885⟩
Epigenetics direct transdifferentiation To make an entire animal, many and varied cell types form and interact. Some of these differentiated cells take a U-turn and can de-differentiate or transdifferentiate to another cell fate. Although relatively
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::018c57ede4a0c6450838dc4e3eb08deb
https://hal.archives-ouvertes.fr/hal-02944411
https://hal.archives-ouvertes.fr/hal-02944411
Autor:
Philippe Robin, Raphaël Margueron, Slimane Ait-Si-Ali, Chiara Mozzetta, Lauriane Fritsch, Manuela Portoso, Julien Pontis, Caroline Proux
Publikováno v:
Molecular Cell
Molecular Cell, Elsevier, 2014, 53 (2), pp.277-289. ⟨10.1016/j.molcel.2013.12.005⟩
Molecular Cell, Elsevier, 2014, 53 (2), pp.277-289. ⟨10.1016/j.molcel.2013.12.005⟩
G9a/GLP and Polycomb Repressive Complex 2 (PRC2) are two major epigenetic silencing machineries, which in particular methylate histone H3 on lysines 9 and 27 (H3K9 and H3K27), respectively. Although evidence of a crosstalk between H3K9 and H3K27 meth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0c37d82b598c310858bf1f06be5eac1
https://hal.archives-ouvertes.fr/hal-03051642
https://hal.archives-ouvertes.fr/hal-03051642
Autor:
Maarten van Lohuizen, Giacomo Cavalli, Manuela Portoso, Bas Tolhuis, Benjamin Leblanc, Rami Jaschek, Mythily Ganapathi, Bernd Schuettengruber, Amos Tanay
Publikováno v:
PLoS Biology
PLoS Biology, Public Library of Science, 2009, 7 (1), pp.e13. ⟨10.1371/journal.pbio.1000013⟩
PLoS Biology, Vol 7, Iss 1, p e13 (2009)
PLoS Biology, Public Library of Science, 2009, 7 (1), pp.e13. ⟨10.1371/journal.pbio.1000013⟩
PLoS Biology, Vol 7, Iss 1, p e13 (2009)
Polycomb group (PcG) and trithorax group (trxG) proteins are conserved chromatin factors that regulate key developmental genes throughout development. In Drosophila, PcG and trxG factors bind to regulatory DNA elements called PcG and trxG response el
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00f30646127293e2c94ad26496c8ad93
https://hal.archives-ouvertes.fr/hal-00357174/file/pbio.1000013.pdf
https://hal.archives-ouvertes.fr/hal-00357174/file/pbio.1000013.pdf
Autor:
Karl Ekwall, Ingela Djupedal, Manuela Portoso, Robin C. Allshire, Claes M. Gustafsson, Henrik Spåhr, Carolina Bonilla
Publikováno v:
Genesdevelopment. 19(19)
Fission yeast centromeric repeats are transcribed into small interfering RNA (siRNA) precursors (pre-siRNAs), which are processed by Dicer to direct heterochromatin formation. Recently, Rpb1 and Rpb2 subunits of RNA polymerase II (RNA Pol II) were sh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc62f704d1e0d70a3e37f0a7e50d1d1c
https://pubmed.ncbi.nlm.nih.gov/16204182
https://pubmed.ncbi.nlm.nih.gov/16204182