Zobrazeno 1 - 10
of 238
pro vyhledávání: '"Manuel Vidal‐Sanz"'
Autor:
María Norte-Muñoz, David García-Bernal, Diego García-Ayuso, Manuel Vidal-Sanz, Marta Agudo-Barriuso
Publikováno v:
Neural Regeneration Research, Vol 19, Iss 3, Pp 542-547 (2024)
Advanced mesenchymal stromal cell-based therapies for neurodegenerative diseases are widely investigated in preclinical models. Mesenchymal stromal cells are well positioned as therapeutics because they address the underlying mechanisms of neurodegen
Externí odkaz:
https://doaj.org/article/0c2637441d334828851f590531bcc312
Autor:
Diego García-Ayuso, Johnny Di Pierdomenico, Ana Martínez-Vacas, Manuel Vidal-Sanz, Serge Picaud, María P Villegas-Pérez
Publikováno v:
Neural Regeneration Research, Vol 19, Iss 3, Pp 606-610 (2024)
Taurine is considered a non-essential amino acid because it is synthesized by most mammals. However, dietary intake of taurine may be necessary to achieve the physiological levels required for the development, maintenance, and function of certain tis
Externí odkaz:
https://doaj.org/article/a7a9178a15e04afb82ed176ed8cce0f4
Autor:
Johnny Di Pierdomenico, Alejandro Gallego-Ortega, María Norte-Muñoz, Beatriz Vidal-Villegas, Isaac Bravo, María Boluda-Ruiz, Jose Manuel Bernal-Garro, Iván Fernandez-Bueno, Jose Carlos Pastor-Jimeno, María Paz Villegas-Pérez, Marcelino Avilés-Trigueros, Cristobal de los Ríos, Manuel Vidal-Sanz
Publikováno v:
Frontiers in Neuroanatomy, Vol 18 (2024)
PurposeThe aim of this study was to investigate, the neuroprotective effects of a new Gramine derivative named: ITH12657, in a model of retinal excitotoxicity induced by intravitreal injection of NMDA.MethodsAdult Sprague Dawley rats received an intr
Externí odkaz:
https://doaj.org/article/e6efdf246d1f4f608e8f4701b382fe5d
Autor:
Kristy T. Rodríguez-Ramírez, María Norte-Muñoz, Fernando Lucas-Ruiz, Alejandro Gallego-Ortega, Francesco Calzaferri, David García-Bernal, Carlos M. Martínez, Caridad Galindo-Romero, Cristóbal de los Ríos, Manuel Vidal-Sanz, Marta Agudo-Barriuso
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
BackgroundNeurological dysfunction and glial activation are common in severe infections such as sepsis. There is a sexual dimorphism in the response to systemic inflammation in both patients and animal models, but there are few comparative studies. H
Externí odkaz:
https://doaj.org/article/5bea71dc8bc24dea91e20bde40d942b6
Autor:
María Norte-Muñoz, Alejandro Gallego-Ortega, Fernando Lucas-Ruiz, María J. González-Riquelme, Yazmín I. Changa-Espinoza, Caridad Galindo-Romero, Peter Ponsaerts, Manuel Vidal-Sanz, David García-Bernal, Marta Agudo-Barriuso
Publikováno v:
Stem Cell Research & Therapy, Vol 13, Iss 1, Pp 1-19 (2022)
Abstract Background Advanced therapies using adult mesenchymal stromal cells (MSCs) for neurodegenerative diseases are not effectively translated into the clinic. The cross talk between the transplanted cells and the host tissue is something that, de
Externí odkaz:
https://doaj.org/article/6b43085bbe104809970a4cc3c903792a
Autor:
Diego Garcia-Ayuso, Johnny Di Pierdomenico, David García-Bernal, Manuel Vidal-Sanz, María P Villegas-Pérez
Publikováno v:
Neural Regeneration Research, Vol 17, Iss 9, Pp 1937-1944 (2022)
Retinal degenerative diseases affecting the outer retina in its many forms (inherited, acquired or induced) are characterized by photoreceptor loss, and represent currently a leading cause of irreversible vision loss in the world. At present, there a
Externí odkaz:
https://doaj.org/article/8ce291e09f30484891e4606c20f1e711
Autor:
Alejandro Gallego-Ortega, María Norte-Muñoz, Johnny Di Pierdomenico, Marcelino Avilés-Trigueros, Pedro de la Villa, Francisco Javier Valiente-Soriano, Manuel Vidal-Sanz
Publikováno v:
Frontiers in Neuroanatomy, Vol 16 (2022)
Purpose: To identify and characterize numerically and topographically the population of alpha retinal ganglion cells (αRGCs) and their subtypes, the sustained-response ON-center αRGCs (ONs-αRGCs), which correspond to the type 4 intrinsically photo
Externí odkaz:
https://doaj.org/article/40b0a8f92eaa4d139151550187f87555
Autor:
Ana Martínez-Vacas, Johnny Di Pierdomenico, Alejandro Gallego-Ortega, Francisco J. Valiente-Soriano, Manuel Vidal-Sanz, Serge Picaud, María Paz Villegas-Pérez, Diego García-Ayuso
Publikováno v:
Redox Biology, Vol 57, Iss , Pp 102506- (2022)
The aim of our work was to study whether taurine administration has neuroprotective effects in dystrophic Royal College of Surgeons (RCS) rats, suffering retinal degeneration secondary to impaired retinal pigment epithelium phagocytosis caused by a M
Externí odkaz:
https://doaj.org/article/1574450e4ef4420baaddb04cbc8590f1
Autor:
Caridad Galindo-Romero, María Norte-Muñoz, Alejandro Gallego-Ortega, Kristy T. Rodríguez-Ramírez, Fernando Lucas-Ruiz, María Josefa González-Riquelme, Manuel Vidal-Sanz, Marta Agudo-Barriuso
Publikováno v:
Frontiers in Neuroanatomy, Vol 16 (2022)
Albino and pigmented rat strains are widely used in models to study retinal degeneration and to test new therapies. Here, we have summarized the main topographical and functional characteristics of the rat retina focussing on photoreceptors and retin
Externí odkaz:
https://doaj.org/article/54776339b5b94dda9e8ab56b01101a2b
Autor:
Yayi Wang, Shida Chen, Jiawei Wang, Yaoming Liu, Yang Chen, Tao Wen, Xiuli Fang, Manuel Vidal-Sanz, Jost B. Jonas, Xiulan Zhang
Publikováno v:
Cell Death and Disease, Vol 12, Iss 1, Pp 1-12 (2021)
Abstract Glaucoma is a common neurodegenerative disease and a leading cause of irreversible blindness worldwide. Retinal microglia-mediated neuroinflammation is involved in the process of optic nerve damage, but the mechanisms driving this microglial
Externí odkaz:
https://doaj.org/article/61648d93315443e59d9d84a9e5b94e43