Zobrazeno 1 - 10
of 115
pro vyhledávání: '"Manuel Valladares-Ayerbes"'
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 11, p 6220 (2024)
The cancer stem cell (SC) theory proposes that a population of SCs serves as the driving force behind fundamental tumor processes, including metastasis, recurrence, and resistance to therapy. The standard of care for patients with stage III and high-
Externí odkaz:
https://doaj.org/article/69924e0798f5461fbd1b6eb2c7b2ca1e
Autor:
Raquel Castosa, Olaia Martinez-Iglesias, Daniel Roca-Lema, Alba Casas-Pais, Andrea Díaz-Díaz, Pilar Iglesias, Isabel Santamarina, Begoña Graña, Lourdes Calvo, Manuel Valladares-Ayerbes, Ángel Concha, Angélica Figueroa
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-10 (2018)
Abstract At early stages of carcinoma progression, epithelial cells undergo a program named epithelial-to-mesenchymal transition characterized by the loss of the major component of the adherens junctions, E-cadherin, which in consequence causes the d
Externí odkaz:
https://doaj.org/article/2673c8d402fa48a18d278383f492cfe5
Autor:
Moisés Blanco-Calvo, Ángel Concha, Angélica Figueroa, Federico Garrido, Manuel Valladares-Ayerbes
Publikováno v:
International Journal of Molecular Sciences, Vol 16, Iss 6, Pp 13610-13632 (2015)
Colorectal cancer is a heterogeneous disease that manifests through diverse clinical scenarios. During many years, our knowledge about the variability of colorectal tumors was limited to the histopathological analysis from which generic classificatio
Externí odkaz:
https://doaj.org/article/90b72e181c9e4d518dac7c4e6fe42bfa
Autor:
Moisés Blanco-Calvo, Lourdes Calvo, Angélica Figueroa, Mar Haz-Conde, Luis Antón-Aparicio, Manuel Valladares-Ayerbes
Publikováno v:
Sensors, Vol 12, Iss 7, Pp 9349-9362 (2012)
MicroRNAs (miRNAs) are small molecules of single strand non-coding RNAs, which are able to regulate gene expression. miRNAs have been involved in multiple cellular processes, such as proliferation, apoptosis and differentiation, thus alterations in m
Externí odkaz:
https://doaj.org/article/d50998d306314d4ab114df057ff160da
Autor:
Luis M. Antón Aparicio, Guadalupe Aparicio Gallego, Manuel Valladares-Ayerbes, Isabel Santamarina Cainzos, Vanessa Medina Villaamil
Publikováno v:
International Journal of Molecular Sciences, Vol 13, Iss 6, Pp 6561-6581 (2012)
In the last several years, researchers have exhibited an intense interest in the evolutionarily conserved signaling pathways that have crucial roles during embryonic development. Interestingly, the malfunctioning of these signaling pathways leads to
Externí odkaz:
https://doaj.org/article/ab69f8a910be4f34b7ea87b3862066f0
Autor:
Sonia Pértega, Angélica Figueroa, Luis M. Antón-Aparicio, Isabel Santamarina, Vanessa Medina, Silvia Díaz-Prado, Mar Haz, Pilar Iglesias-Díaz, María J. Lorenzo-Patiño, Margarita Reboredo, Manuel Valladares-Ayerbes, Moisés Blanco-Calvo
Publikováno v:
International Journal of Molecular Sciences, Vol 13, Iss 4, Pp 4367-4387 (2012)
We aim to estimate the diagnostic performances of anterior gradient homolog-2 (AGR2) and Leucine-rich repeat-containing-G-protein-coupled receptor 5 (LGR5) in peripheral blood (PB) as mRNA biomarkers in colorectal cancer (CRC) and to explore their pr
Externí odkaz:
https://doaj.org/article/7a9bcc53010b420c8657c74672618079
Autor:
Antonieta Salud, Manuel Valladares-Ayerbes, Javier Sastre, Elena Asensio, Luis Robles, Eduardo Díaz-Rubio, Fernando Rivera, Enrique Aranda, Albert Abad, Auxiliadora Gómez-España, Vicente Alonso-Orduña, Alfredo Carrato, Clara Montagut, Maria Jose Safont, Cristina García González, Manuel Benavides, Encarnación González-Flores, Pilar García-Alfonso, Jose María Vieitez
Publikováno v:
European Journal of Surgical Oncology. 48:1123-1132
Retrospective studies and meta-analyses suggest that upfront primary tumour resection (UPTR) confers a survival benefit in patients with asymptomatic unresectable metastatic colorectal cancer (mCRC) undergoing chemotherapy, however a consensus of its
Autor:
Manuel Valladares-Ayerbes, Pilar Garcia-Alfonso, Jorge Muñoz Luengo, Paola Patricia Pimentel Caceres, Oscar Alfredo Castillo Trujillo, Rosario Vidal-Tocino, Marta Llanos, Beatriz Llorente Ayala, Maria Luisa Limon Miron, Antonieta Salud, Luis Cirera Nogueras, Rocio Garcia-Carbonero, Maria Jose Safont, Esther Falco Ferrer, Jorge Aparicio, Maria Angeles Vicente Conesa, Carmen Guillén-Ponce, Paula Garcia-Teijido, Maria Begoña Medina Magan, Isabel Busquier, Mercedes Salgado, Ariadna Lloansí Vila
Publikováno v:
Cancers; Volume 14; Issue 24; Pages: 6075
The serial analysis of cell-free DNA (cfDNA) enables minimally invasive monitoring of tumor evolution, providing continuous genetic information. PERSEIDA was an observational, prospective study assessing the cfDNA RAS (KRAS/NRAS) mutational status ev
Autor:
Manuel, Valladares-Ayerbes, Pilar, Garcia-Alfonso, Jorge, Muñoz Luengo, Paola Patricia, Pimentel Caceres, Oscar Alfredo, Castillo Trujillo, Rosario, Vidal-Tocino, Marta, Llanos, Beatriz, Llorente Ayala, Maria Luisa, Limon Miron, Antonieta, Salud, Luis, Cirera Nogueras, Rocio, Garcia-Carbonero, Maria Jose, Safont, Esther, Falco Ferrer, Jorge, Aparicio, Maria Angeles, Vicente Conesa, Carmen, Guillén-Ponce, Paula, Garcia-Teijido, Maria Begoña, Medina Magan, Isabel, Busquier, Mercedes, Salgado, Ariadna, Lloansí Vila
Publikováno v:
Cancers. 14(24)
The serial analysis of cell-free DNA (cfDNA) enables minimally invasive monitoring of tumor evolution, providing continuous genetic information. PERSEIDA was an observational, prospective study assessing the cfDNA
Autor:
Guillem Argilés, Nuria Mulet, Manuel Valladares-Ayerbes, José M. Viéitez, Cristina Grávalos, Pilar García-Alfonso, Cristina Santos, María Tobeña, Beatriz García-Paredes, Manuel Benavides, María T. Cano, Fotios Loupakis, Mercedes Rodríguez-Garrote, Fernando Rivera, Richard M. Goldberg, Chiara Cremolini, Jaafar Bennouna, Fortunato Ciardiello, Josep M. Tabernero, Enrique Aranda, Josep Tabernero, Alfredo Falcone, Richard Goldberg, null Argilés, J. Tabernero, N. Mulet, M.L. Limón, M. Valladares, P. Jiménez, J. Ma Vieitez, C. Grávalos, P. García-Alfonso, C. Santos, D. Páez, M. Tobeña, J. Sastre, B. García Paredes, M. Benavides, E. Aranda, M.T. Cano, F. Loupakis, M. Rguez Garrote, C. Guillén, Ma F. Rivera, J. Safont, S. Hiret, J. Bennouna, D. Pannier, D. Malka, A. Falcone, C. Cremolini
Publikováno v:
Scientia
Purpose: The purpose of this article is to evaluate the safety of two regorafenib dose-escalation approaches in refractory metastatic colorectal cancer (mCRC) patients.Patients and methods: Patients with mCRC and progression during or within 3 months
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8bd05f70988e5ca895198e0724218256
https://hdl.handle.net/11591/486122
https://hdl.handle.net/11591/486122