Zobrazeno 1 - 10
of 61
pro vyhledávání: '"Manuel T. Silva"'
Publikováno v:
Toxins, Vol 2, Iss 4, Pp 905-918 (2010)
Photobacterium damselae subsp. piscicida (Phdp) is a Gram-negative pathogen agent of an important fish septicemia. The key virulence factor of Phdp is the plasmid-encoded exotoxin AIP56, which is secreted by exponentially growing pathogenic strains.
Externí odkaz:
https://doaj.org/article/7b591e6bd8b549b09bde47fee33fd630
Publikováno v:
Frontiers in Immunology, Vol 3 (2012)
Biological cellular systems are groups of cells sharing a set of characteristics, mainly key function and origin. Phagocytes are crucial in the host defense against microbial infection. The previously proposed phagocyte cell systems including the mos
Externí odkaz:
https://doaj.org/article/11b5a880bcb840589975214b7900372e
Autor:
Manuel T. Silva
Publikováno v:
Frontiers in Microbiology, Vol 3 (2012)
An ample understanding of the complex interactions between host and pathogen will improve our ability to develop new prophylactic and therapeutic measures against infection.Precise classification of infectious agents in regards to their infective lif
Externí odkaz:
https://doaj.org/article/b25712e5bc8342768d535055e2622139
Autor:
Egídio Torrado, Wayne M. Meyers, Françoise Portaels, António G. Castro, Jorge Pedrosa, Margarida Saraiva, Andrea Cruz, Alexandra G. Fraga, Manuel T. Silva, Teresa G. Martins, Daniela Maria Ramos Pereira
Publikováno v:
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Buruli ulcer (BU) is a neglected infectious disease caused by Mycobacterium ulcerans, characterized by necrotic cutaneous lesions induced by the exotoxin mycolactone. Despite evidence of Th1-mediated protective immunity, M. ulcerans infection has bee
Publikováno v:
Toxins, Vol 2, Iss 4, Pp 905-918 (2010)
Toxins
Toxins
Photobacterium damselae subsp. piscicida (Phdp) is a Gram-negative pathogen agent of an important fish septicemia. The key virulence factor of Phdp is the plasmid-encoded exotoxin AIP56, which is secreted by exponentially growing pathogenic strains.
Autor:
Manuel T. Silva
Publikováno v:
Journal of Leukocyte Biology. 87:805-813
Neutrophils and macrophages cooperate as inducers and effectors of adaptive immune responses to infection by microbial extracellular and intracellular pathogens in the context of TH1, TH17, and TH17/TH1 responses. Emerging data suggest new facets of
Autor:
Manuel T. Silva
Publikováno v:
Journal of Leukocyte Biology. 87:93-106
The presence of two dedicated phagocytic cells working cooperatively represents an advantageous innate immune strategy that allows the efficient and safe utilization of powerful but dangerous microbicidal molecules. The antimicrobial effector activit
Publikováno v:
Apoptosis
In metazoans apoptosis is a major physiological process of cell elimination during development and in tissue homeostasis and can be involved in pathological situations. In vitro, apoptosis proceeds through an execution phase during which cell dismant
Publikováno v:
Current Pharmaceutical Design. 14:170-183
The relevance of fish research has been rising due to the expansion of aquaculture and to the increasing use of fish as replacements for mammals in the study of human physiological and pathological issues. Fish have much smaller genomes compared to m
Autor:
Cristina Pinto, Diana S. Nascimento, Ana do Vale, Marta I.R. Reis, Carolina Costa-Ramos, Manuel T. Silva, Daniela S.P. Silva, Nuno M.S. dos Santos
Publikováno v:
Molecular Immunology. 44:1754-1764
Caspase-9 is an initiator caspase in the apoptotic process whose function is to activate effector caspases that are downstream in the mitochondrial pathway of apoptosis. This work reports for the first time the complete sequencing and characterisatio