Zobrazeno 1 - 10
of 61
pro vyhledávání: '"Manuel T Silva"'
Autor:
José B Gama, Steffen Ohlmeier, Teresa G Martins, Alexandra G Fraga, Belém Sampaio-Marques, Maria A Carvalho, Fernanda Proença, Manuel T Silva, Jorge Pedrosa, Paula Ludovico
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 8, Iss 8, p e3066 (2014)
Buruli ulcer (BU) is a neglected tropical disease caused by Mycobacterium ulcerans. The tissue damage characteristic of BU lesions is known to be driven by the secretion of the potent lipidic exotoxin mycolactone. However, the molecular action of myc
Externí odkaz:
https://doaj.org/article/81a6f8cacfe2453398ad3e0a46d84e0f
Autor:
Sophie Gryseels, Diana Amissah, Lies Durnez, Koen Vandelannoote, Herwig Leirs, Johan De Jonckheere, Manuel T Silva, Françoise Portaels, Anthony Ablordey, Miriam Eddyani
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 6, Iss 8, p e1764 (2012)
BackgroundThe reservoir and mode of transmission of Mycobacterium ulcerans, the causative agent of Buruli ulcer, remain unknown. Ecological, genetic and epidemiological information nonetheless suggests that M. ulcerans may reside in aquatic protozoa.
Externí odkaz:
https://doaj.org/article/25ac801bf54f495c99c6185a4d6bdbb5
Autor:
Teresa G Martins, Gabriela Trigo, Alexandra G Fraga, José B Gama, Adhemar Longatto-Filho, Margarida Saraiva, Manuel T Silva, António G Castro, Jorge Pedrosa
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 6, Iss 11, p e1925 (2012)
BACKGROUND: Buruli ulcer (BU) is a necrotizing disease of the skin, subcutaneous tissue and bone caused by Mycobacterium ulcerans. It has been suggested that the immune response developed during the recommended rifampicin/streptomycin (RS) antibiothe
Externí odkaz:
https://doaj.org/article/61e658b992504d9688351ad0dcef2868
Autor:
Alexandra G Fraga, Teresa G Martins, Egídio Torrado, Kris Huygen, Françoise Portaels, Manuel T Silva, António G Castro, Jorge Pedrosa
Publikováno v:
PLoS ONE, Vol 7, Iss 3, p e33406 (2012)
BACKGROUND: Buruli ulcer (BU) is an emerging infectious disease caused by Mycobacterium ulcerans that can result in extensive necrotizing cutaneous lesions due to the cytotoxic exotoxin mycolactone. There is no specific vaccine against BU but reports
Externí odkaz:
https://doaj.org/article/1655f4a264024190b872658baf97a5ca
Autor:
Teresa G Martins, José B Gama, Alexandra G Fraga, Margarida Saraiva, Manuel T Silva, António G Castro, Jorge Pedrosa
Publikováno v:
PLoS ONE, Vol 7, Iss 2, p e32740 (2012)
BACKGROUND: Buruli ulcer (BU) is a neglected necrotizing disease of the skin, subcutaneous tissue and bone, caused by Mycobacterium ulcerans. BU pathogenesis is associated with mycolactone, a lipidic exotoxin with cytotoxic and immunosuppressive prop
Externí odkaz:
https://doaj.org/article/55537e58934642fc9aed77bc780db359
Autor:
Françoise Portaels, Wayne M Meyers, Anthony Ablordey, António G Castro, Karim Chemlal, Pim de Rijk, Pierre Elsen, Krista Fissette, Alexandra G Fraga, Richard Lee, Engy Mahrous, Pamela L C Small, Pieter Stragier, Egídio Torrado, Anita Van Aerde, Manuel T Silva, Jorge Pedrosa
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 2, Iss 3, p e178 (2008)
BACKGROUND: Mycobacterium ulcerans disease, or Buruli ulcer (BU), is an indolent, necrotizing infection of skin, subcutaneous tissue and, occasionally, bones. It is the third most common human mycobacteriosis worldwide, after tuberculosis and leprosy
Externí odkaz:
https://doaj.org/article/6b7b68ab19fd49ec902c86acc5dab4b5
Publikováno v:
PLoS Medicine, Vol 4, Iss 2, p e63 (2007)
Externí odkaz:
https://doaj.org/article/84c819bdbc7147989f133c4f0129169a
Autor:
Egídio Torrado, Wayne M. Meyers, Françoise Portaels, António G. Castro, Jorge Pedrosa, Margarida Saraiva, Andrea Cruz, Alexandra G. Fraga, Manuel T. Silva, Teresa G. Martins, Daniela Maria Ramos Pereira
Publikováno v:
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Buruli ulcer (BU) is a neglected infectious disease caused by Mycobacterium ulcerans, characterized by necrotic cutaneous lesions induced by the exotoxin mycolactone. Despite evidence of Th1-mediated protective immunity, M. ulcerans infection has bee
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2842d69ed11ec4d8207f0a9caeac7528
https://doi.org/10.1128/iai.00820-10
https://doi.org/10.1128/iai.00820-10
Publikováno v:
Toxins, Vol 2, Iss 4, Pp 905-918 (2010)
Toxins
Toxins
Photobacterium damselae subsp. piscicida (Phdp) is a Gram-negative pathogen agent of an important fish septicemia. The key virulence factor of Phdp is the plasmid-encoded exotoxin AIP56, which is secreted by exponentially growing pathogenic strains.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::146b42efafd4741217e1d26ee8c6418e
http://www.mdpi.com/2072-6651/2/4/905/
http://www.mdpi.com/2072-6651/2/4/905/
Autor:
Manuel T. Silva
Publikováno v:
Journal of Leukocyte Biology. 87:805-813
Neutrophils and macrophages cooperate as inducers and effectors of adaptive immune responses to infection by microbial extracellular and intracellular pathogens in the context of TH1, TH17, and TH17/TH1 responses. Emerging data suggest new facets of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f73263897bcfe3c36f35b8ef6ea5ee3
https://doi.org/10.1189/jlb.1109767
https://doi.org/10.1189/jlb.1109767