Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Manuel Strach"'
Publikováno v:
BMC Biology, Vol 21, Iss 1, Pp 1-22 (2023)
Abstract Background Whereas the translocation of proteins across the cell membrane has been thoroughly investigated, it is still unclear how proteins cross the cell wall in Gram-positive bacteria, which are widely used for industrial applications. We
Externí odkaz:
https://doaj.org/article/f8d78df25cb7400cb30879aff810c7c3
Autor:
Fabian Grein, Anna Müller, Katharina M. Scherer, Xinliang Liu, Kevin C. Ludwig, Anna Klöckner, Manuel Strach, Hans-Georg Sahl, Ulrich Kubitscheck, Tanja Schneider
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-11 (2020)
The mechanism of action of daptomycin, a lipopeptidic antibiotic, is unclear. Here, the authors show that Ca2+-daptomycin simultaneously interacts with lipid-coupled precursors of the bacterial cell envelope and with the anionic phospholipid phosphat
Externí odkaz:
https://doaj.org/article/3f8afa07193d465fb47aa48692257131
Whereas the translocation of proteins across the cell membrane has been thoroughly investigated, it is still unclear how proteins cross the cell wall in Gram positive bacteria, which are widely used for industrial applications. We have studied secret
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::028f20c279ba39b7b1a4872cb9c9964c
https://doi.org/10.21203/rs.3.rs-2021376/v1
https://doi.org/10.21203/rs.3.rs-2021376/v1
Autor:
Fabian, Grein, Anna, Müller, Katharina M, Scherer, Xinliang, Liu, Kevin C, Ludwig, Anna, Klöckner, Manuel, Strach, Hans-Georg, Sahl, Ulrich, Kubitscheck, Tanja, Schneider
Publikováno v:
Nature Communications
The lipopeptide daptomycin is used as an antibiotic to treat severe infections with gram-positive pathogens, such as methicillin resistant Staphylococcus aureus (MRSA) and drug-resistant enterococci. Its precise mechanism of action is incompletely un