Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Manuel Saldivia"'
Autor:
Vincent Geoghegan, Juliana B. T. Carnielli, Nathaniel G. Jones, Manuel Saldivia, Sergios Antoniou, Charlotte Hughes, Rachel Neish, Adam Dowle, Jeremy C. Mottram
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-17 (2022)
Combination of proximity biotinylation and protein cross-linking allows proximity phosphoproteomics of the kinetochore in Leishmania parasites during the cell cycle and captures perturbations at the kinetochore after treatment with a protein kinase i
Externí odkaz:
https://doaj.org/article/8ed4bba9584b41d385a7ad7f0d9506f1
Autor:
Manuel Saldivia, Adam J. M. Wollman, Juliana B. T. Carnielli, Nathaniel G. Jones, Mark C. Leake, Christopher Bower-Lepts, Srinivasa P. S. Rao, Jeremy C. Mottram
Publikováno v:
mBio, Vol 12, Iss 3 (2021)
In eukaryotic cells, kinetochores are large protein complexes that link chromosomes to dynamic microtubule tips, ensuring proper segregation and genomic stability during cell division. Several proteins tightly coordinate kinetochore functions, includ
Externí odkaz:
https://doaj.org/article/86905287e15d4286a26051507d71d700
Publikováno v:
Cell Reports, Vol 17, Iss 3, Pp 660-670 (2016)
During infection in mammals, the protozoan parasite Trypanosoma brucei transforms from a proliferative bloodstream form to a quiescent form that is pre-adapted to host transition. AMP analogs are known to induce quiescence and also inhibit TbTOR4. To
Externí odkaz:
https://doaj.org/article/75340ac5c06a44988442762d1be1b62d
Autor:
Rosario Diaz-Gonzalez, F Matthew Kuhlmann, Cristina Galan-Rodriguez, Luciana Madeira da Silva, Manuel Saldivia, Caitlin E Karver, Ana Rodriguez, Stephen M Beverley, Miguel Navarro, Michael P Pollastri
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 5, Iss 8, p e1297 (2011)
Target repurposing utilizes knowledge of "druggable" targets obtained in one organism and exploits this information to pursue new potential drug targets in other organisms. Here we describe such studies to evaluate whether inhibitors targeting the ki
Externí odkaz:
https://doaj.org/article/e7d2dde1c328442f9eb247b65f5c0bb9
Publikováno v:
Current Journal of Applied Science and Technology. :72-91
The Puma concolor is one of the largest carnivores present in Chile, although its size varies according to the geographical area in which it is found. It is increasingly common to find them outside their habitat and more in our environment. Its ecolo
Publikováno v:
Revista de Medicina Veterinaria, Issue: 41, Pages: 105-91, Published: 07 MAR 2021
Resumen Otodectes cynotis es uno de los ácaros responsables de causar dermatosis parasitaria en el pabellón auricular en animales de compañía, lo que les produce prurito intenso e incluso complicaciones óticas por falta del tratamiento adecuado.
Autor:
Xiaolei Ma, Christopher Bower-Lepts, Jeremy C. Mottram, Frantisek Supek, Eric Fang, Elmarie Myburgh, Marcel Kaiser, Manuel Saldivia, Michael P. Barrett, Daniel Paape, Thierry T. Diagana, Yen Liang Chen, Suresh B Lakhsminarayana, Jan Jiricek, Ryan Ritchie, Elizabeth Ornelas, Richard McCulloch, Srinivasa P. S. Rao, Hazel X. Y. Koh, Debjani Patra, Juliana B.T. Carnielli, Sarah Williams, Elaine Brown
Publikováno v:
Nature microbiology
The kinetochore is a macromolecular structure that assembles on the centromeres of chromosomes and provides the major attachment point for spindle microtubules during mitosis. In Trypanosoma brucei the proteins that make up the kinetochore are highly
Autor:
Manuel Saldivia
Publikováno v:
Revista de Medicina Veterinaria. 1:3-4
El propósito del siguiente estudio consiste en realizar una descripción anatómica del neurocráneo de animales mayores, enfocado en el equino (Equus caballus) y el bovino (Bos taurus.). El neurocráneo es un complejo articular óseo, que permite p
Autor:
Manuel Saldivia
Publikováno v:
Revista de Medicina Veterinaria. 1:5-6
El siguiente estudio consistió en realizar una descripción anatómica de los segmentos óseos del esplacnocráneo de animales mayores, enfocándose en el equino (Equus caballus) y el bovino (Bos taurus). El cráneo constituye el esqueleto óseo de
Autor:
Manuel Saldivia Paredes
Publikováno v:
Revista de Medicina Veterinaria. 1:1-9
espanolResumen Este estudio tiene el objetivo de demostrar la perdida de sensibilidad en la pared abdominal izquierda y primer cuarto craneal, en hembras bovinas productoras de leche sometidas a laparotomia por el flanco izquierdo con histerotomia, m