Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Manuel Rodriguez‐Perálvarez"'
Autor:
Juan L. López‐Cánovas, Natalia Hermán‐Sánchez, Maria Trinidad Moreno‐Montilla, Mercedes del Rio‐Moreno, Emilia Alors‐Perez, Marina E. Sánchez‐Frias, Víctor Amado, Rubén Ciria, Javier Briceño, Manuel de laMata, Justo P. Castaño, Manuel Rodriguez‐Perálvarez, Raúl M. Luque, Manuel D. Gahete
Publikováno v:
Clinical and Translational Medicine, Vol 12, Iss 11, Pp n/a-n/a (2022)
Abstract Introduction Altered splicing landscape is an emerging cancer hallmark; however, the dysregulation and implication of the cellular machinery controlling this process (spliceosome components and splicing factors) in hepatocellular carcinoma (
Externí odkaz:
https://doaj.org/article/44c65a5a43f5401cba4cff96e19ce370
Autor:
Juan L. López-Cánovas, Natalia Hermán-Sánchez, Mercedes del Rio-Moreno, Antonio C. Fuentes-Fayos, Araceli Lara-López, Marina E. Sánchez-Frias, Víctor Amado, Rubén Ciria, Javier Briceño, Manuel de la Mata, Justo P. Castaño, Manuel Rodriguez-Perálvarez, Raúl M. Luque, Manuel D. Gahete
Publikováno v:
Experimental & Molecular Medicine. 55:132-142
Hepatocellular carcinoma (HCC) pathogenesis is associated with alterations in splicing machinery components (spliceosome and splicing factors) and aberrant expression of oncogenic splice variants. We aimed to analyze the expression and potential role
Autor:
Juan L, López-Cánovas, Natalia, Hermán-Sánchez, Mercedes, Del Rio-Moreno, Antonio C, Fuentes-Fayos, Araceli, Lara-López, Marina E, Sánchez-Frias, Víctor, Amado, Rubén, Ciria, Javier, Briceño, Manuel, de la Mata, Justo P, Castaño, Manuel, Rodriguez-Perálvarez, Raúl M, Luque, Manuel D, Gahete
Publikováno v:
Experimentalmolecular medicine.
Hepatocellular carcinoma (HCC) pathogenesis is associated with alterations in splicing machinery components (spliceosome and splicing factors) and aberrant expression of oncogenic splice variants. We aimed to analyze the expression and potential role
Autor:
Lorena Puchades, MD, Julia Herreras, MD, Maria Àngels Cebrià i Iranzo, MD, PhD, Érick Reyes, MD, Gonzalo Crespo, MD, PhD, Manuel Rodríguez-Perálvarez, MD, PhD, Luis Cortés, MD, Trinidad Serrano, MD, PhD, Ainhoa Fernández-Yunquera, MD, Eva Montalvá, MD, PhD, Marina Berenguer, MD, PhD
Publikováno v:
Transplantation Direct, Vol 10, Iss 4, p e1599 (2024)
Introduction. Until now, there has been limited evidence, primarily from US cohorts, focusing on frailty as a patient-oriented outcome after liver transplantation (LT). Our study aimed to explore the relationship between pre- and post-LT frailty in a
Externí odkaz:
https://doaj.org/article/1adde68425074bb59e5e08d3adb57136
Autor:
Lorena Puchades, Julia Herreras, Ana Ibañez, Érick Reyes, Gonzalo Crespo, Manuel Rodríguez-Perálvarez, Luis Cortés, Trinidad Serrano, Ainhoa Fernández-Yunquera, Eva Montalvá, Marina Berenguer
Publikováno v:
JHEP Reports, Vol 5, Iss 11, Pp 100840- (2023)
Background & Aims: Frailty is prevalent in liver transplant (LT) candidates. It is considered an independent predictor of adverse outcomes pre- and post-transplant according to data obtained in the United States. We aimed to externally validate the l
Externí odkaz:
https://doaj.org/article/d3b8c4e4877a4dec891c2e28e19a24e6
Autor:
Laura‐Patricia Llovet, Jordi Gratacós‐Ginès, Luis Téllez, Ana Gómez‐Outomuro, Carmen A. Navascués, Mar Riveiro‐Barciela, Raquel Vinuesa, Judith Gómez‐Camarero, Montserrat García‐Retortillo, Fernando Díaz‐Fontenla, Magdalena Salcedo, María García‐Eliz, Diana Horta, Marta Guerrero, Manuel Rodríguez‐Perálvarez, Conrado Fernández‐Rodriguez, Agustín Albillos, Juan G‐Abraldes, Albert Parés, Maria‐Carlota Londoño
Publikováno v:
Hepatology Communications, Vol 6, Iss 6, Pp 1392-1402 (2022)
The value of noninvasive tools in the diagnosis of autoimmune hepatitis (AIH)–related cirrhosis and the prediction of clinical outcomes is largely unknown. We sought to evaluate (1) the utility of liver stiffness measurement (LSM) in the diagnosis
Externí odkaz:
https://doaj.org/article/f8c14bab24664d2cb80b095d921eff50
Autor:
María Lola Espejo-Cruz, Sandra González-Rubio, Javier Zamora-Olaya, Víctor Amado-Torres, Rafael Alejandre, Marina Sánchez-Frías, Rubén Ciria, Manuel De la Mata, Manuel Rodríguez-Perálvarez, Gustavo Ferrín
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 23, p 13073 (2021)
Hepatocellular carcinoma (HCC) is the fifth most common neoplasm and a major cause of cancer-related death worldwide. There is no ideal biomarker allowing early diagnosis of HCC and tumor surveillance in patients receiving therapy. Liquid biopsy, and
Externí odkaz:
https://doaj.org/article/90d42c5975e1464781467d95d2959675
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 4, p 1266 (2020)
Hepatocellular carcinoma (HCC) is the most frequent primary liver cancer and occurs mainly in patients with liver cirrhosis. The mammalian target of rapamycin (mTOR) signaling pathway is involved in many hallmarks of cancer including cell growth, met
Externí odkaz:
https://doaj.org/article/84aab368fd434bd1b67be1c509b14413
Autor:
Pablo Pérez, Manuel Rodríguez-Perálvarez, Lourdes Guerrero, Víctor González, Rafael Sánchez, Macarena Centeno, Antonio Poyato, Javier Briceño, Marina Sánchez-Frías, Jose Luis Montero, Manuel De la Mata
Publikováno v:
PLoS ONE, Vol 12, Iss 4, p e0175010 (2017)
BACKGROUND:Incidental hepatocellular carcinoma (iHCC) is a histological finding after liver transplantation (LT) which relevance has been scarcely studied. AIMS:to describe the histopathological features of iHCC and to determine its prognostic impact
Externí odkaz:
https://doaj.org/article/a7d392a37787482d8ad63a26d3e177f3
Autor:
Marta Guerrero, Gustavo Ferrín, Manuel Rodríguez-Perálvarez, Sandra González-Rubio, Marina Sánchez-Frías, Víctor Amado, Juan C. Pozo, Antonio Poyato, Rubén Ciria, María D. Ayllón, Pilar Barrera, José L. Montero, Manuel de la Mata
Publikováno v:
International Journal of Molecular Sciences, Vol 20, Iss 2, p 336 (2019)
(1) Background: The mammalian target of rapamycin (mTOR) pathway activation is critical for hepatocellular carcinoma (HCC) progression. We aimed to evaluate the mTOR tissue expression in liver transplant (LT) patients and to analyse its influence on
Externí odkaz:
https://doaj.org/article/c0c896e1bff2476887f08d1cb211934a