Adjunct prednisone in community-acquired pneumonia: 180-day outcome of a multicentre, double-blind, randomized, placebo-controlled trial

Autor: Claudine A. Blum, Eva A. Roethlisberger, Nicole Cesana-Nigro, Bettina Winzeler, Nicolas Rodondi, Manuel R. Blum, Matthias Briel, Beat Mueller, Mirjam Christ-Crain, Philipp Schuetz

Publikováno v: BMC Pulmonary Medicine, Vol 23, Iss 1, Pp 1-12 (2023)

Abstract Background Several trials and meta-analyses found a benefit of adjunct corticosteroids for community-acquired pneumonia with respect to short-term outcome, but there is uncertainty about longer-term health effects. Herein, we evaluated clini

Externí odkaz: https://doaj.org/article/e7c13ba4ed6e475fae45dea938d10faf

Lipid‐Lowering Therapy and Risk of Hemorrhagic Stroke: A Systematic Review and Meta‐Analysis of Randomized Controlled Trials

Autor: Sylvain Bétrisey, Moa Lina Haller, Orestis Efthimiou, Alexandre Speierer, Cinzia Del Giovane, Elisavet Moutzouri, Manuel R. Blum, Drahomir Aujesky, Nicolas Rodondi, Baris Gencer

Publikováno v: Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 13, Iss 4 (2024)

Background There is debate over whether statins increase risk of hemorrhagic stroke, so we assessed current evidence, including data from new statin trials and trials of nonstatin low‐density lipoprotein‐cholesterol (LDL‐C)– and triglyceride�

Externí odkaz: https://doaj.org/article/be23f50ad5a54995a798ef0f58518ec6

Achilles tendon ultrasonography in the clinical screening of familial hypercholesterolaemia – a cross-sectional analysis

Autor: Maria de Montmollin, Sylvain Bétrisey, Martin Feller, Elisavet Moutzouri, Manuel R. Blum, Jennifer Amsler, Dimitrios D. Papazoglou, Burkhard Möller, Nicolas Rodondi

Publikováno v: Swiss Medical Weekly, Vol 153, Iss 11 (2023)

BACKGROUND AND AIMS: People with familial hypercholesterolaemia are 13 times more likely to develop cardiovascular disease than the general population. However, familial hypercholesterolaemia remains largely underdiagnosed. Tendon xanthoma is a speci

Externí odkaz: https://doaj.org/article/eb8302cf37b24795a414d1f3dec7693e

Bone Morphogenetic Protein 10—A Novel Biomarker to Predict Adverse Outcomes in Patients With Atrial Fibrillation

Autor: Elisa Hennings, Steffen Blum, Stefanie Aeschbacher, Michael Coslovsky, Sven Knecht, Ceylan Eken, Mirko Lischer, Rebecca E. Paladini, Philipp Krisai, Tobias Reichlin, Nicolas Rodondi, Jürg H. Beer, Peter Ammann, Giulio Conte, Maria Luisa De Perna, Richard Kobza, Manuel R. Blum, Matthias Bossard, Peter Kastner, André Ziegler, Christian Müller, Leo H. Bonati, Otmar Pfister, Christine S. Zuern, David Conen, Michael Kühne, Stefan Osswald

Publikováno v: Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 12, Iss 6 (2023)

Background Patients with atrial fibrillation (AF) face an increased risk of death and major adverse cardiovascular events (MACE). We aimed to assess the predictive value of the novel atrial‐specific biomarker BMP10 (bone morphogenetic protein 10) f

Externí odkaz: https://doaj.org/article/d445e72bc653465dbf0b297fd8b69208

Sex differences of vascular brain lesions in patients with atrial fibrillation

Autor: Christian Müller, Leo H Bonati, Pascal Meyre, Steffen Blum, Stefanie Aeschbacher, David Conen, Stefan Osswald, Urs Fischer, Manuel R Blum, Simon Jung, Jens Wuerfel, Christian Sticherling, Michael Kuhne, Philipp Krisai, Matthias Schwenkglenks, Luise Adam, Elisavet Moutzouri, Martin Feller, Nathalie Schwab, Claudio Schneider, Drahomir Aujesky, Nicolas Rodondi, Karl-Olof Lovblad, Michael Amann, Richard Kobza, Marie Méan, Andreas Müller, Giorgio Moschovitis, Fabienne Witassek, Silke Küest, Sonja Meier, Jürg-Hans Beer, Damiana Rakovic, Michael Coslovsky, Tiziano Moccetti, Ramun Schmid, Augusto Gallino, Carole Elodie Aubert, Georg Ehret, Angelo Auricchio, Giulio Conte, Daniel Hayoz, Benjamin Berte, Nathalie Lauriers, Peter Ammann, François Regoli, Dipen Shah, Laurent Roten, Marco Düring, Pascal Benkert, Simone Evers-Dörpfeld, Elisa Hennings, Ceylan Eken, Selinda Ceylan, Anne Springer, Heinrich Mattle, Tim Sinnecker, Leo Bonati, Anna Altermatt, Manuel Blum, Sacha Niederberger, Chloé Auberson, Simone Evers-Doerpfeld, Marc Girod, Elena Herber, Vasco Iten, Mirko Lischer, Christine Meyer-Zürn, Andreas U Monsch, Thomas Szucs, Gian Völlmin, Juerg Fuhrer, Axel Loewe, Tanja Flückiger, Cindy Groen, Lukas Ehrsam, Sven Hellrigl, Alexandra Nuoffer, Rylana Wenger, Christopher Beynon, Roger Dillier, Michèle Deubelbeiss, Franz Eberli, Christine Franzini, Isabel Juchli, Claudia Liedtke, Jacqueline Nadler, Thayze Obst, Jasmin Roth, Fiona Schlomowitsch, Xiaoye Schneider, Katrin Studerus, Noreen Tynan, Dominik Weishaupt, Simone Fontana, Karin Scheuch, Denise Hischier, Nicole Bonetti, Alexandra Grau, Jonas Villinger, Eva Laube, Philipp Baumgartner, Mark Filipovic, Marcel Frick, Giulia Montrasio, Stefanie Leuenberger, Franziska Rutz, Adriana Anesini, Cristina Camporini, Maria Luce Caputo, Roman Brenner, David Altmann, Michaela Gemperle, Mathieu Firmann, Sandrine Foucras, Martine Rime, Virgina Justi, Frauke Kellner-Weldon, Brigitta Mehmann, Myriam Roth, Andrea Ruckli-Kaeppeli, Ian Russi, Kai Schmidt, Mabelle Young, Melanie Zbinden, Luisa Vicari, Hervé Gallet, Elise Guillermet, Francois Lazeyras, Patrick Perret, Philippe Tavel, Cheryl Teres, Sandrine Salzmann, Jürg Schläpfer, Andrea Grêt, Jan Novak, Sandra Vitelli, Frank-Peter Stephan, Jane Frangi-Kultalahti, Marcello Di Valentino, Jens Würfel, Petra Huber, Esther Ruberte, Vanessa Zuber, Gilles Dutilh, Milica Markovic, Pia Neuschwander, Patrick Simon

Publikováno v: Open Heart, Vol 9, Iss 2 (2022)

Objective To examine sex differences in prevalence, volume and distribution of vascular brain lesions on MRI among patients with atrial fibrillation (AF).Methods In this cross-sectional analysis, we included 1743 patients with AF (27% women) from the

Externí odkaz: https://doaj.org/article/b73f1541a93e40d498515f2bba783d7b