Zobrazeno 1 - 10
of 171
pro vyhledávání: '"Manuel Perucho"'
Autor:
Beatriz González, Maria Navarro-Jiménez, María José Alonso-De Gennaro, Sanne Marcia Jansen, Isabel Granada, Manuel Perucho, Sergio Alonso
Publikováno v:
Cancers, Vol 13, Iss 21, p 5353 (2021)
Somatic DNA hypomethylation and aneuploidy are hallmarks of cancer, and there is evidence for a causal relationship between them in knockout mice but not in human cancer. The non-mobile pericentromeric repetitive elements SST1 are hypomethylated in a
Externí odkaz:
https://doaj.org/article/1273cbe6e959447fbfd2d9c82c722e6c
Publikováno v:
Epigenetics, Vol 12, Iss 7, Pp 515-526 (2017)
Abundant repetitive DNA sequences are an enigmatic part of the human genome. Despite increasing evidence on the functionality of DNA repeats, their biologic role is still elusive and under frequent debate. Macrosatellites are the largest of the tande
Externí odkaz:
https://doaj.org/article/f792c665006c47a8ae6c77a763259394
Autor:
Luis M Real, Agustín Ruiz, Javier Gayán, Antonio González-Pérez, María E Sáez, Reposo Ramírez-Lorca, Francisco J Morón, Juan Velasco, Ruth Marginet-Flinch, Eva Musulén, José M Carrasco, Concha Moreno-Rey, Enrique Vázquez, Manuel Chaves-Conde, Jose A Moreno-Nogueira, Manuel Hidalgo-Pascual, Eduardo Ferrero-Herrero, Sergi Castellví-Bel, Antoni Castells, Ceres Fernandez-Rozadilla, Clara Ruiz-Ponte, Angel Carracedo, Beatriz González, Sergio Alonso, Manuel Perucho
Publikováno v:
PLoS ONE, Vol 9, Iss 6, p e101178 (2014)
BackgroundNon-hereditary colorectal cancer (CRC) is a complex disorder resulting from the combination of genetic and non-genetic factors. Genome-wide association studies (GWAS) are useful for identifying such genetic susceptibility factors. However,
Externí odkaz:
https://doaj.org/article/5263b15232e048de89f66f787f7df1c3
Autor:
Wenyun Zhou, Sergio Alonso, Daisaku Takai, Shelly C Lu, Fumiichiro Yamamoto, Manuel Perucho, Shi Huang
Publikováno v:
PLoS ONE, Vol 3, Iss 10, p e3390 (2008)
The typical Western diet is not balanced in methyl nutrients that regulate the level of the methyl donor S-adenosylmethionine (SAM) and its derivative metabolite S-adenosylhomocysteine (SAH), which in turn may control the activity of certain methyltr
Externí odkaz:
https://doaj.org/article/ec171dcb225e4bf68ebffc1d785ef61f
Autor:
Marcus Buschbeck, Julien Douet, Sònia-Vanina Forcales, Victor Moreno, Manuel Perucho, Miquel Angel Peinado, Vanesa Valero, Eva Musulén, Neus Cantariño
Contains supplemental methods and materials, 2 figures, a table and supplemental references. Figure 1. Preliminary evidence suggesting that PADI2 re-expression in colon cancer cells conveys sensitivity to calcium treatment. Figure S2. The association
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d119bfd22131ebbdf6f4640e626876a
https://doi.org/10.1158/1541-7786.22513876
https://doi.org/10.1158/1541-7786.22513876
Publikováno v:
Methods. 187:68-76
Super resolution microscopy has changed our capability to visualize and understand spatial arrangements of RNA- and protein-containing domains in individual cells. In a previous study, we described a novel lncRNA, Tumor-associated NBL2 transcript (TN
Autor:
Jordi Valls-Margarit, Iván Galván-Femenía, Daniel Matías-Sánchez, Natalia Blay, Montserrat Puiggròs, Anna Carreras, Cecilia Salvoro, Beatriz Cortés, Ramon Amela, Xavier Farre, Jon Lerga-Jaso, Marta Puig, Jose Francisco Sánchez-Herrero, Victor Moreno, Manuel Perucho, Lauro Sumoy, Lluís Armengol, Olivier Delaneau, Mario Cáceres, Rafael de Cid, David Torrents
Publikováno v:
Nucleic Acids Research
r-IGTP. Repositorio Institucional de Producción Científica del Instituto de Investigación Germans Trias i Pujol
instname
UPCommons. Portal del coneixement obert de la UPC
Universitat Politècnica de Catalunya (UPC)
r-IGTP. Repositorio Institucional de Producción Científica del Instituto de Investigación Germans Trias i Pujol
instname
UPCommons. Portal del coneixement obert de la UPC
Universitat Politècnica de Catalunya (UPC)
The combined analysis of haplotype panels with phenotype clinical cohorts is a common approach to explore the genetic architecture of human diseases. However, genetic studies are mainly based on single nucleotide variants (SNVs) and small insertions
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5ba8ea97c0da40374c640eb94b47c91
https://hdl.handle.net/2117/364556
https://hdl.handle.net/2117/364556
Autor:
Sanne Marcia Jansen, Beatriz González, Sergio Alonso, Isabel Granada, Manuel Perucho, María José Alonso-De Gennaro, Maria Navarro-Jiménez
Publikováno v:
Cancers, Vol 13, Iss 5353, p 5353 (2021)
Cancers; Volume 13; Issue 21; Pages: 5353
Cancers
r-IGTP. Repositorio Institucional de Producción Científica del Instituto de Investigación Germans Trias i Pujol
instname
Cancers; Volume 13; Issue 21; Pages: 5353
Cancers
r-IGTP. Repositorio Institucional de Producción Científica del Instituto de Investigación Germans Trias i Pujol
instname
Simple Summary Cancer cells frequently exhibit an abnormal number of chromosomes, termed aneuploidy, often preceded by an aberrant genome duplication resulting in cells with double the number of chromosomes (tetraploidy). The cause of the aberrant ge
Autor:
Jordi Valls-Margarit, Marta Sabariego Puig, Manuel Perucho, David Torrents, Cecilia Salvoro, Xavier Farré, Beatriz Cortés, Olivier Delaneau, Anna Carreras, Rafael de Cid, Jon Lerga-Jaso, Daniel Matías-Sánchez, Mario Cáceres, Victor Moreno, Montserrat Puiggròs, Lauro Sumoy, Lluís Armengol, Natalia Blay, Ramon Amela, Iván Galván-Femenía, Jose Francisco Sánchez-Herrero
The combined analysis of haplotype panels with phenotype clinical cohorts is a common approach to explore the genetic architecture of human diseases. However, genetic studies are mainly based on single nucleotide variants (SNVs) and small insertions
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::db62edc524f949631eefb84ab30b2b83
https://doi.org/10.1101/2021.07.20.453041
https://doi.org/10.1101/2021.07.20.453041
Autor:
Jörn Wilms, Eduardo Ros, Christian M. Fromm, Manuel Perucho, Robert Schulz, Anne Kathrin Baczko, Matthias Kadler
Context: Few Active Galactic Nuclei (AGN) reveal a double sided jet system. However, these are crucial to understand basic physical properties of extragalactic jets. Aims: We address the questions whether jets in AGN are symmetric in nature, how well
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06c11a83421d0f3fa2c341b5eafa0ae7