Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Manuel Ottiger"'
Autor:
Seline Zurfluh, Manuela Nickler, Manuel Ottiger, Christian Steuer, Alexander Kutz, Mirjam Christ-Crain, Werner Zimmerli, Robert Thomann, Claus Hoess, Christoph Henzen, Luca Bernasconi, Andreas Huber, Beat Mueller, Philipp Schuetz, for the proHOSP study group
Publikováno v:
Respiratory Research, Vol 19, Iss 1, Pp 1-10 (2018)
Abstract Background Adrenal hormone metabolite levels are altered in acute illnesses such as community-acquired pneumonia (CAP). Our aim was to investigate associations of sex and mineralocorticoid hormone metabolites with short- and long-term mortal
Externí odkaz:
https://doaj.org/article/647a1affaac84d0b845ecf6f25e746f5
Autor:
Alaadin Voegeli, Beat Mueller, Luca Bernasconi, Marc A. Meier, Seline Zurfluh, Manuel Ottiger, Peter Neyer, Philipp Schuetz, Thomas Baumgartner
Publikováno v:
Expert Review of Anti-infective Therapy. 16:133-142
Metabolomics is a rapidly growing area of research. Metabolomic markers can provide information about the interaction of different organ systems, and thereby improve the understanding of physio-pathological processes, disease risk, prognosis and ther
Autor:
Philipp Schuetz, Manuela Nickler, Mirjam Christ-Crain, Christoph Henzen, Werner Zimmerli, Beat Mueller, Christian Steuer, Claus Hoess, Manuel Ottiger, Jonas Odermatt, Robert Thomann, Andreas Huber
Publikováno v:
European Journal of Internal Medicine. 36:67-73
Introduction The pro-atherosclerotic metabolite trimethylamine-N-oxide (TMAO) is a risk factor for incident cardiovascular events and a potentially modifiable mediator of chronic inflammation through broad-spectrum antibiotic treatment by changing th
Autor:
Heiner C. Bucher, Jonas Odermatt, Manuel Ottiger, Beat Mueller, Philipp Schuetz, Rebekka Bolliger, Lara Hersberger, Mirjam Christ-Crain, Matthias Briel
Background: Copeptin, the C-terminal part of the arginine vasopressin (AVP) precursor peptide, is secreted in response to stress and correlates with adverse clinical outcomes in the acute-care hospital setting. There are no comprehensive data regardi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91aaa259726b5cf51997128858db35fc
http://doc.rero.ch/record/325261/files/cclm-2016-0151.pdf
http://doc.rero.ch/record/325261/files/cclm-2016-0151.pdf
Autor:
Philipp Schuetz, Beat Mueller, Claus Hoess, Robert Thomann, Mirjam Christ-Crain, Manuela Nickler, Christoph Henzen, Daniela Schaffner, Manuel Ottiger
Publikováno v:
Clinical Chemistry and Laboratory Medicine (CCLM). 54:1831-1846
Background: Most clinical research investigated prognostic biomarkers for their ability to predict cardiovascular events or mortality. It is unknown whether biomarkers allow prediction of quality of life (QoL) after survival of the acute event. Herei
Autor:
Christian Steuer, Alexander Kutz, Philipp Schuetz, Manuela Nickler, Robert Thomann, Mirjam Christ-Crain, Seline Zurfluh, Beat Mueller, Manuel Ottiger, Christoph Henzen, Werner Zimmerli, Andreas Huber, Luca Bernasconi, Claus Hoess
Publikováno v:
Clinical chemistry and laboratory medicineReferences. 56(4)
Background: The release of hormones from the adrenal gland is vital in acute and chronic illnesses such as chronic obstructive pulmonary disease (COPD) involving recurrent exacerbations. Using a metabolomic approach, we aim to investigate association
Autor:
Mirjam Christ-Crain, Christoph Henzen, Manuel Ottiger, Luca Bernasconi, Marc A. Meier, Werner Zimmerli, Philipp Schuetz, Claus Hoess, Christian Steuer, Andreas Huber, Beat Mueller, Alaadin Vögeli, Robert Thomann
Publikováno v:
Lung. 195(6)
In chronic obstructive pulmonary disease (COPD), there is an activation of the l-arginine nitric oxide pathway. Pulmonary obstruction causes to elevated nitric oxide (NO) levels, which lead to higher production of the NO-inhibiting metabolites asymme
Autor:
Andreas Huber, Philipp Schuetz, Luca Bernasconi, Mirjam Christ-Crain, Christoph Henzen, Claus Hoess, Christian Steuer, Marc A. Meier, Manuel Ottiger, Werner Zimmerli, Alaadin Vögeli, Robert Thomann, Beat Mueller
Background:As part of the immune defense during infection, an increase in enzyme activity of indoleamine 2,3-dioxygenase (IDO) leads to a breakdown of tryptophan to kynurenine. In previous animal studies, therapeutic antagonism of IDO resulted in red
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43fe19a9c4904d42ada0231a440eb3fb
https://edoc.unibas.ch/55128/
https://edoc.unibas.ch/55128/
Autor:
Werner Zimmerli, Christian Steuer, Mirjam Christ-Crain, Christoph Henzen, Claus Hoess, Robert Thomann, Luca Bernasconi, Andreas Huber, Manuel Ottiger, Marc A. Meier, Philipp Schuetz, Alaadin Vögeli, Beat Mueller
Publikováno v:
Lung. 195(3)
Indoleamine 2,3-dioxygenase (IDO) metabolizes tryptophan to kynurenine. An increase of its activity is associated with severity in patients with pneumonia. In chronic obstructive pulmonary disease (COPD) patients, an elevation of serotonin has been r
Autor:
Robert Thomann, Luca Bernasconi, Alaadin Vögeli, Marc A. Meier, Mirjam Christ-Crain, Christoph Henzen, Werner Zimmerli, Philipp Schuetz, Manuel Ottiger, Prasad Kulkarni, Beat Mueller, Christian Steuer, Claus Hoess, Andreas Huber
Publikováno v:
Respiratory Research
During infection, there is an activation of the L-arginine-nitric-oxide pathway, with a shift from nitric oxide synthesis to a degradation of L-arginine to its metabolites, asymmetric and symmetric dimethylarginine (ADMA and SDMA). However, the progn