Mitochondrial Dynamics in Mitochondrial Diseases

Autor: Juan M. Suárez-Rivero, Marina Villanueva-Paz, Patricia de la Cruz-Ojeda, Mario de la Mata, David Cotán, Manuel Oropesa-Ávila, Isabel de Lavera, Mónica Álvarez-Córdoba, Raquel Luzón-Hidalgo, José A. Sánchez-Alcázar

Publikováno v: Diseases, Vol 5, Iss 1, p 1 (2016)

Mitochondria are very versatile organelles in continuous fusion and fission processes in response to various cellular signals. Mitochondrial dynamics, including mitochondrial fission/fusion, movements and turnover, are essential for the mitochondrial

Externí odkaz: https://doaj.org/article/3df88e2133fe42f0870ddf1760f4159a

The Effect of Copper on Endometrial Receptivity and Induction of Apoptosis on Decidualized Human Endometrial Stromal Cells

Autor: Inmaculada Jurado, Pascual Sánchez-Martín, José A. Horcajadas, Justin Tan, Manuel Oropesa-Ávila, Seang L. Tan, David Cotán, José P. Carrascosa, José Antonio Sánchez-Alcázar, Ricardo Francalacci Savaris

Publikováno v: Digital.CSIC. Repositorio Institucional del CSIC
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Digital.CSIC: Repositorio Institucional del CSIC
Consejo Superior de Investigaciones Científicas (CSIC)

Intrauterine devices (IUDs) have been widely used to prevent pregnancies with great efficacy during decades. It has been demonstrated that IUD alters the endometrial gene expression, but there is no scientific data about how copper, a metal commonly

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3105bd1685b9697fa6b639c0a62d4fff
https://doi.org/10.1177/1933719117732165

Targeting autophagy and mitophagy for mitochondrial diseases treatment

Autor: Mario de la Mata, Juan Garrido-Maraver, Manuel Oropesa-Ávila, José Antonio Sánchez-Alcázar, Elizabet Alcocer-Gómez, Mario D. Cordero, Isabel de Lavera, Ana Delgado Pavón, Marina Villanueva Paz, David Cotán

Publikováno v: Digital.CSIC. Repositorio Institucional del CSIC
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[Introduction]: Mitochondrial diseases are a group of rare genetic diseases with complex and heterogeneous origins which manifest a great variety of phenotypes. Disruption of the oxidative phosphorylation system is the main cause of pathogenicity in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c77a601eaaab683aef948297bde64b1
https://doi.org/10.1517/14728222.2016.1101068

The Connections Among Autophagy, Inflammasome and Mitochondria

Autor: Elizabet Alcocer-Gómez, Juan Garrido-Maraver, Marina Villanueva Paz, Isabel de Lavera, Mario de la Mata, David Cotán, José Antonio Sánchez-Alcázar, Ana Delgado Pavón, Mónica Álvarez-Córdoba, Manuel Oropesa-Ávila

Publikováno v: Digital.CSIC. Repositorio Institucional del CSIC
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[Background]: The molecular crosstalk between inflammation and autophagy is an emerging field of research that is essential for the understanding of multicellular organism homeostasis and how these processes influence a variety of pathological condit

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7de286c0ffd023f20b739a9856d53b97
https://doi.org/10.2174/1389450117666160527143143

Stabilization Of Apoptotic Cells: Generation Of Zombie Cells

Autor: Juan Garrido Maraver, Manuel Oropesa Ávila, Yuniesky Andrade Talavera, Mario de la Mata, Marina Villanueva Paz, Isabel de Lavera, José A. Sánchez Alcázar, Antonio Rodríguez Moreno, Elisabet Alcocer Gómez, David Cotán, Ana Delgado Pavón

Publikováno v: Redox Biology, Vol 5, Iss, Pp 416-(2015)

Apoptosis is characterized by degradation of cell components but plasma membrane remains intact. Apoptotic microtubule network (AMN) is organized during apoptosis forming a cortical structure beneath plasma membrane that maintains plasma membrane int

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b732198ab1214d103c10dda4ce568835
https://pubmed.ncbi.nlm.nih.gov/28162276