Zobrazeno 1 - 10
of 105
pro vyhledávání: '"Manuel Mameli"'
Autor:
Katia Monsorno, Kyllian Ginggen, Andranik Ivanov, An Buckinx, Arnaud L. Lalive, Anna Tchenio, Sam Benson, Marc Vendrell, Angelo D’Alessandro, Dieter Beule, Luc Pellerin, Manuel Mameli, Rosa Chiara Paolicelli
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-18 (2023)
Abstract Microglia, the innate immune cells of the central nervous system, actively participate in brain development by supporting neuronal maturation and refining synaptic connections. These cells are emerging as highly metabolically flexible, able
Externí odkaz:
https://doaj.org/article/ca1e699ffea54efa99b93749b51797b1
Publikováno v:
Translational Psychiatry, Vol 12, Iss 1, Pp 1-8 (2022)
Abstract Throughout life, individuals experience a vast array of positive and aversive events that trigger adaptive behavioural responses. These events are often unpredicted and engage actions that are likely anchored on innate behavioural programs e
Externí odkaz:
https://doaj.org/article/85b141f09a4340b98f4e6c1ed7f11f8e
Publikováno v:
Frontiers in Behavioral Neuroscience, Vol 16 (2022)
Externí odkaz:
https://doaj.org/article/742ca95408484c2da586d475d6963b0f
Autor:
Jürgen Germann, Manuel Mameli, Gavin J. B. Elias, Aaron Loh, Alaa Taha, Flavia Venetucci Gouveia, Alexandre Boutet, Andres M. Lozano
Publikováno v:
Frontiers in Psychiatry, Vol 12 (2021)
The habenula is a small bilateral epithalamic structure that plays a key role in the regulation of the main monoaminergic systems. It is implicated in many aspects of behavior such as reward processing, motivational behavior, behavioral adaptation, a
Externí odkaz:
https://doaj.org/article/d70075e6fd71446bbc1d7978d34c7492
Autor:
Nuria Domínguez-Iturza, Adrian C. Lo, Disha Shah, Marcelo Armendáriz, Anna Vannelli, Valentina Mercaldo, Massimo Trusel, Ka Wan Li, Denise Gastaldo, Ana Rita Santos, Zsuzsanna Callaerts-Vegh, Rudi D’Hooge, Manuel Mameli, Annemie Van der Linden, August B. Smit, Tilmann Achsel, Claudia Bagni
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
In humans, copy-number variants of the CYFIP1 gene have been associated with autism spectrum disorders and schizophrenia. Here, the authors characterize Cyfip1-heterozygous mice, revealing that they display deficits in brain white matter structure an
Externí odkaz:
https://doaj.org/article/45ce8718dbe54af7bd35ef3ffe5acc3a
Autor:
Joseph Clerke, Patricia Preston-Ferrer, Ioannis S. Zouridis, Audrey Tissot, Laura Batti, Fabian F. Voigt, Stephane Pagès, Andrea Burgalossi, Manuel Mameli
Publikováno v:
Frontiers in Synaptic Neuroscience, Vol 13 (2021)
Projections from the lateral habenula (LHb) control ventral tegmental area (VTA) neuronal populations’ activity and both nuclei shape the pathological behaviors emerging during cocaine withdrawal. However, it is unknown whether cocaine withdrawal m
Externí odkaz:
https://doaj.org/article/efeb4dcd7e054e56b7e2e6ff7ea7d279
Publikováno v:
Translational Psychiatry, Vol 12, Iss 1, Pp 1-1 (2022)
Externí odkaz:
https://doaj.org/article/00a309fd37bb4f289149305c86e50606
Autor:
Yo Otsu, Salvatore Lecca, Katarzyna Pietrajtis, Charly Vincent Rousseau, Païkan Marcaggi, Guillaume Pierre Dugué, Caroline Mailhes-Hamon, Manuel Mameli, Marco Alberto Diana
Publikováno v:
Cell Reports, Vol 22, Iss 3, Pp 693-705 (2018)
The medial habenula (MHb) is an epithalamic hub contributing to expression and extinction of aversive states by bridging forebrain areas and midbrain monoaminergic centers. Although contradictory information exists regarding their synaptic properties
Externí odkaz:
https://doaj.org/article/601b4beaf6ad4b49b843e5a8aa3059e9
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-8 (2017)
Early-life stress primes depression in adulthood. This study shows that early maternal separation leads to lateral habenula (LHb) hyperactivity and causes depressive-like phenotypes, the latter being reversible when LHb hyperactivity is reduced chemo
Externí odkaz:
https://doaj.org/article/936450413b8840da904071ec58df9446
Autor:
Kristina Valentinova, Manuel Mameli
Publikováno v:
Cell Reports, Vol 16, Iss 9, Pp 2298-2307 (2016)
Excitatory and inhibitory transmission onto lateral habenula (LHb) neurons is instrumental for the expression of positive and negative motivational states. However, insights into the molecular mechanisms modulating synaptic transmission and the reper
Externí odkaz:
https://doaj.org/article/b9980e04d917403c9afee3334185aaae