Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Manuel Kanitz"'
Autor:
Andreas Heine, Sandra Blanck, Manuel Kanitz, Wibke E. Diederich, Alexander E. Gorbalenya, Anastasia A. Gulyaeva, John Ziebuhr
Publikováno v:
Virology, 533, 21-33
Virology
Virology
Cavally virus (CavV) is a mosquito-borne plus-strand RNA virus in the family Mesoniviridae (order Nidovirales). We present X-ray structures for the CavV 3C-like protease (3CLpro), as a free enzyme and in complex with a peptide aldehyde inhibitor mimi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58222649b23922f664660b67b00d79f1
https://doi.org/10.1016/j.virol.2019.05.001
https://doi.org/10.1016/j.virol.2019.05.001
Autor:
Hongmei, Wu, Stefanie, Bock, Mariya, Snitko, Thilo, Berger, Thomas, Weidner, Steven, Holloway, Manuel, Kanitz, Wibke E, Diederich, Holger, Steuber, Christof, Walter, Daniela, Hofmann, Benedikt, Weißbrich, Ralf, Spannaus, Eliana G, Acosta, Ralf, Bartenschlager, Bernd, Engels, Tanja, Schirmeister, Jochen, Bodem
Publikováno v:
Antimicrobial agents and chemotherapy. 59(2)
Dengue fever is a severe, widespread, and neglected disease with more than 2 million diagnosed infections per year. The dengue virus NS2B/NS3 protease (PR) represents a prime target for rational drug design. At the moment, there are no clinical PR in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::18f4b1f29152c9c6646813821b3d9738
https://pubmed.ncbi.nlm.nih.gov/25487800
https://pubmed.ncbi.nlm.nih.gov/25487800
Publikováno v:
Topics in Medicinal Chemistry ISBN: 9783662467589
Targeting viral proteases represents an attractive concept in the field of anti-infective lead discovery and has been exploited successfully yielding a number of drugs on the market. Next to their essential role in degrading the virus-encoded polypro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::aa35797f137f5eb6b93666f434beafba
https://doi.org/10.1007/7355_2014_46
https://doi.org/10.1007/7355_2014_46
