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pro vyhledávání: '"Manuel Jara-Espejo"'
Most multicellular organisms reproduce sexually despite the costs associated with sexuality1. This has been explained as the result of selection favouring the ability to recombine the genome. The lack of recombination in asexual species constrains th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a40dcf49a499a9cdd02b355c8c181df1
https://doi.org/10.1101/2023.03.20.533553
https://doi.org/10.1101/2023.03.20.533553
Autor:
Manuel Jara-Espejo, Sergio Roberto Peres Line, Melissa T. R. Hawkins, Giovani Bressan Fogalli
Publikováno v:
Molecular Biology and Evolution
Eutherian dentition has been the focus of a great deal of studies in the areas of evolution, development, and genomics. The development of molar teeth is regulated by an antero-to-posterior cascade mechanism of activators and inhibitors molecules, wh
While non-coding G-quadruplexes (G4s) act as conserved regulatory elements when located in gene promoter and splice sites, the G4 evolutionary conservation in protein coding regions have been low explored. To address the evolutionary dynamics acting
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6d998dc70816ff094427952c66ea7752
https://doi.org/10.1101/2020.08.28.272971
https://doi.org/10.1101/2020.08.28.272971
Publikováno v:
Biochemistry. 59(28)
Sequences of DNA typically adopt B-form duplexes in genomes, although noncanonical structures such as G-quadruplexes, i-motifs, Z-DNA, and cruciform structures can occur. A challenge is to determine the functions of these various structures in cellul
Publikováno v:
ACS Chemical Biology
Maturation of mRNA in humans involves modifying the 5′ and 3′ ends, splicing introns, and installing epitranscriptomic modifications that are essential for mRNA biogenesis. With respect to epitranscriptomic modifications, they are usually install
Maturation of mRNA in humans involves modifying the 5' and 3' ends, splicing introns, and installing epitranscriptomic modifications that are essential for mRNA biogenesis. With respect to epitranscriptomic modifications, they are usually installed i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1a89a24fccd1dc272fbeaf34904b97b
Publikováno v:
The FEBS journalReferences. 287(3)
CpG islands (CGI) are genomic regions associated with gene promoters and involved in gene expression regulation. Despite their high CpG content and unlike bulk genomic DNA methylation pattern, these regions are usually hypomethylated. So far, the mec