Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Manuel J. T. Carrondo"'
Autor:
Nicolas Collin, Donata Medaglini, Arjen Sloots, Maria Lawrenz, Jan A.M. Langermans, Roger Le Grand, Norbert Stockhofe-Zurwieden, Francesca Morelli, Fabrice Laurent, Frédéric Lantier, Alexandre Dobly, Dennis Christensen, Joaquim Segalés, H. M. Dockrell, Mei Mei Ho, Ole Olesen, Tom H.M. Ottenhoff, Frank A.W. Verreck, Stefan Jungbluth, Sven Arnouts, Manuel J. T. Carrondo, David Morrow, Fran Van Heuverswyn, Carlos A. Guzman, Anton Ussi, Monika Slezak, Hilde Depraetere, William Martin
Publikováno v:
F1000Research, Vol 12 (2023)
Background Research infrastructures are facilities or resources that have proven fundamental for supporting scientific research and innovation. However, they are also known to be very expensive in their establishment, operation and maintenance. As by
Externí odkaz:
https://doaj.org/article/9b023d85cc924663a81aea22af5b7578
Autor:
Petra Mooij, Daniella Mortier, Aafke Aartse, Alexandre B. Murad, Ricardo Correia, António Roldão, Paula M. Alves, Zahra Fagrouch, Dirk Eggink, Norbert Stockhofe, Othmar G. Engelhardt, Ernst J. Verschoor, Marit J. van Gils, Willy M. Bogers, Manuel J. T. Carrondo, Edmond J. Remarque, Gerrit Koopman
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
The first exposure to influenza is presumed to shape the B-cell antibody repertoire, leading to preferential enhancement of the initially formed responses during subsequent exposure to viral variants. Here, we investigated whether this principle rema
Externí odkaz:
https://doaj.org/article/fe0da1bcfd6c40f6beed32ab73a26fdd
Autor:
Salomé Neto, João P. Mendes, Susana B. Dos Santos, Anita Solbrand, Manuel J. T. Carrondo, Cristina Peixoto, Ricardo J. S. Silva
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 11 (2023)
Adeno-associated viruses (AAVs) are one of the most promising tools for gene therapy applications. These vectors are purified using affinity and ion exchange chromatography, typically using packed beds of resin adsorbents. This leads to diffusion and
Externí odkaz:
https://doaj.org/article/4d2723ec4e3c42c1b83ac42378534e38
Autor:
Sofia B. Carvalho, Ricardo J. S. Silva, Marcos F. Q. Sousa, Cristina Peixoto, António Roldão, Manuel J. T. Carrondo, Paula M. Alves
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 10 (2022)
Virus-like particles (VLPs) are excellent platforms for the development of influenza vaccine candidates. Nonetheless, their characterization is challenging due to VLPs’ unique biophysical and biochemical properties. To cope with such complexity, mu
Externí odkaz:
https://doaj.org/article/1941adabf729446ab0a5d18b8aee6648
Autor:
Hugo R. Soares, Rute Castro, Hélio A. Tomás, Manuel J. T. Carrondo, Paula M. Alves, Ana S. Coroadinha
Publikováno v:
AMB Express, Vol 9, Iss 1, Pp 1-7 (2019)
Abstract Hepatitis C virus (HCV) infects 3% of world population being responsible for nearly half a million deaths annually urging the need for a prophylactic vaccine. Retrovirus like particles are commonly used scaffolds for antigens presentation be
Externí odkaz:
https://doaj.org/article/227981efe8ca44df817c0cd2474844c3
Autor:
João P. Mendes, Magnus Bergman, Anita Solbrand, Cristina Peixoto, Manuel J. T. Carrondo, Ricardo J. S. Silva
Publikováno v:
Pharmaceutics, Vol 14, Iss 7, p 1346 (2022)
Replacing batch unit operations of biopharmaceuticals by continuous manufacturing is a maturing concept, with periodic counter-current chromatography (PCC) favoured to replace batch chromatography. Continuous affinity capture of adeno-associated viru
Externí odkaz:
https://doaj.org/article/af19056809b94de4ba6fd2a19c130678
Autor:
Sofia B. Carvalho, Ricardo J. S. Silva, Marcos F. Q. Sousa, Cristina Peixoto, António Roldão, Manuel J. T. Carrondo, Paula M. Alves
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 10 (2022)
Virus-like particles (VLPs) are excellent platforms for the development of influenza vaccine candidates. Nonetheless, their characterization is challenging due to VLPs’ unique biophysical and biochemical properties. To cope with such complexity, mu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7bd5ef5d7cf9fa07bf022769ebf181c3
https://pubmed.ncbi.nlm.nih.gov/35252128
https://pubmed.ncbi.nlm.nih.gov/35252128
Autor:
Alexandre B. Murad, Marcos Q. Sousa, Ricardo Correia, Inês A. Isidro, Manuel J. T. Carrondo, António Roldão
Publikováno v:
Processes; Volume 10; Issue 11; Pages: 2283
Virus-like particles (VLPs) are versatile vaccine carriers for conferring broad protection against influenza by enabling high-level display of multiple hemagglutinin (HA) strains within the same particle construct. The insect cell-baculovirus express
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c7d53d2e5767b579754b1e88da65c02
https://doi.org/10.3390/pr10112283
https://doi.org/10.3390/pr10112283
Autor:
Ricardo J S, Silva, João P, Mendes, Manuel J T, Carrondo, Paula M, Marques, Cristina, Peixoto
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2095
Novel biopharmaceutical products, such as vaccines and viral vectors, play a significant role in the development of innovative therapeutic, prophylactic, and clinical applications. However, several challenges are posed when manufacturing these produc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::eabf6ef1811e8209f5080470404ba22a
https://pubmed.ncbi.nlm.nih.gov/31858479
https://pubmed.ncbi.nlm.nih.gov/31858479
Autor:
Francisca, Arez, Sofia P, Rebelo, Diana, Fontinha, Daniel, Simão, Tatiana R, Martins, Marta, Machado, Christoph, Fischli, Claude, Oeuvray, Lassina, Badolo, Manuel J T, Carrondo, Matthias, Rottmann, Thomas, Spangenberg, Catarina, Brito, Beatrice, Greco, Miguel, Prudêncio, Paula M, Alves
Publikováno v:
ACS infectious diseases. 5(11)
The restricted pipeline of drugs targeting the liver stage of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d860d2f27d8ac4f2d5ace93fc8f42657
https://pubmed.ncbi.nlm.nih.gov/31479238
https://pubmed.ncbi.nlm.nih.gov/31479238