Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Manuel J. Quiñones"'
Autor:
Heinrich R. Schelbert, Thomas H. Schindler, Manuel J. Quiñones, Jerson Cadenas, John O. Prior, Alvaro D. Facta, Willa A. Hsueh
Publikováno v:
Heart. 93:345-349
To determine the effect of plasma glucose lowering on coronary circulatory function in type 2 diabetes mellitus.Twenty patients with type 2 diabetes and 18 weight-matched controls were studied. At baseline, myocardial blood flow (MBF) was measured wi
Autor:
Manuel J. Quiñones, Mark O. Goodarzi, Willa A. Hsueh, Robert I. Jennrich, Noel G. Boyle, Sidney C. Port
Publikováno v:
American Journal of Epidemiology. 163:342-351
Using the Framingham Heart Study data (United States, 1948-1978), the authors examined the association of blood glucose with 2-year all-cause, cardiovascular, and noncardiovascular mortality in subjects with documented cardiovascular disease. After a
Autor:
Willa A. Hsueh, Manuel J. Quiñones, Huiying Yang, Mark O. Goodarzi, Jerome I. Rotter, Heath J. Antoine, Lawrence W. Castellani, Kent D. Taylor, Xiuqing Guo, Howard Wong
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 90:4816-4823
Haplotypes comprising six single nucleotide polymorphisms (SNPs) (intron 7 to intron 9) of the lipoprotein lipase (LPL) gene appear to influence risk for atherosclerosis and insulin resistance in Mexican-Americans.Based on rodent studies, we hypothes
Autor:
Willa A. Hsueh, Alvaro D. Facta, Heinrich R. Schelbert, Miguel Hernandez-Pampaloni, James Sayre, Thomas H. Schindler, John O. Prior, Manuel J. Quiñones
Publikováno v:
Circulation. 111:2291-2298
Background— Abnormal coronary endothelial reactivity has been demonstrated in diabetes and is associated with an increased rate of cardiovascular events. Our objectives were to investigate the presence of functional coronary circulatory abnormaliti
Autor:
Jinrui Cui, Willa A. Hsueh, Manuel J. Quiñones, Xiuqing Guo, Jerome I. Rotter, Mohammad F. Saad, Howard N. Hodis, Yanjie Li, Huiying Yang, Mark O. Goodarzi, Kent D. Taylor
Publikováno v:
Diabetes. 54:1228-1232
The powerful relation between atherosclerosis and diabetes may have a common genetic basis. However, few genes predisposing to both have been identified. Calpain-10 (CAPN10) was the first gene for type 2 diabetes identified by positional cloning, whe
Autor:
Willa A. Hsueh, Isabel Bulnes-Enriquez, Huiying Yang, Katherine Yu, Xochitl Jimenez, Yanjie Li, Dai Wang, Kent D. Taylor, Jerome I. Rotter, Tamara Modilevsky, Roxana De La Rosa, Manuel J. Quiñones, Howard N. Hodis
Publikováno v:
Stroke. 36:540-545
Background and Purpose— Carotid artery intima-media thickness (CIMT), a subclinical measure of atherosclerosis, is associated with coronary artery disease (CAD), and stroke. CIMT is also an important predictor of clinical cardiovascular events. To
Autor:
Willa A. Hsueh, Jerome I. Rotter, Mark O. Goodarzi, Kent D. Taylor, Xiuqing Guo, Manuel J. Quiñones, Mohammad F. Saad, Huiying Yang
Publikováno v:
Diabetes. 53:214-220
The insulin resistance syndrome is increasingly recognized as a risk factor for cardiovascular disease. Lipoprotein lipase (LPL) is a candidate gene for components of the syndrome. A small number of studies have demonstrated association of single nuc
Autor:
Vittorio Sartorelli, Howard Prentice, Laurence Kedes, Manuel J. Quiñones, Michael Patterson, Robert A. Kloner, Jonathan Leor
Publikováno v:
Cardiovascular Research. 35:431-441
Time for primary review 22 days. Despite significant progress in prevention and therapy of ischemic heart disease, treating patients with heart failure after myocardial infarction remains a major therapeutic challenge. Adult cardiomyocytes cannot reg
Publikováno v:
Journal of Molecular and Cellular Cardiology. 28:2057-2067
Gene transfer as a therapeutic modality for the treatment of myocardial ischemia and/or infarction has been proposed as a revolutionary approach to improve collateral circulation, enhance myocardial viability and amplify healing. Our study was undert
Autor:
Manuel J. Quiñones, Joseph Frankhouse, J. Gregory Modrall, Fred A. Weaver, Willa A. Hsueh, Larry Kedes
Publikováno v:
Journal of Surgical Research. 59:135-140
Although the renin-angiotensin system has been implicated in the pathogenesis of renovascular hypertension (RVH), blood pressure does not parallel serum levels of renin or angiotensin II (All) in chronic RVH. Upregulation of angiotensin II type 1 rec