Zobrazeno 1 - 9 of 9 pro vyhledávání: '"Manuel Hidalgo Pascual"'
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A colorectal cancer susceptibility new variant at 4q26 in the Spanish population identified by genome-wide association analysis
Autor: Enrique Vazquez, Manuel Perucho, Manuel Hidalgo-Pascual, Eva Musulen, María Eugenia Sáez, Juan Velasco, Antoni Castells, Agustín Ruiz, Eduardo Ferrero-Herrero, Beatriz González, Javier Gayán, Ruth Marginet-Flinch, Luis Miguel Real, Reposo Ramírez-Lorca, Clara Ruiz-Ponte, José Andrés Moreno-Nogueira, Ceres Fernandez-Rozadilla, Manuel Chaves-Conde, Sergio Alonso, Sergi Castellví-Bel, Concha Moreno-Rey, Antonio González-Pérez, José Miguel Carrasco, Francisco J. Morón, Angel Carracedo
Publikováno v: Recercat. Dipósit de la Recerca de Catalunya
instname
RUNA. Repositorio da Consellería de Sanidade e Sergas
Servizo Galego de Saúde (SERGAS)
PLoS ONE, Vol 9, Iss 6, p e101178 (2014)
Dipòsit Digital de la UB
Universidad de Barcelona
PLoS ONE
BackgroundNon-hereditary colorectal cancer (CRC) is a complex disorder resulting from the combination of genetic and non-genetic factors. Genome-wide association studies (GWAS) are useful for identifying such genetic susceptibility factors. However,
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4fca977d8ab99dd2a93674f5f99bb30c
http://hdl.handle.net/2445/122303
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5
Analysis of the ERalpha germline PvuII marker in breast cancer risk
Autor: Rosario, González-Mancha, Jose Jorge, Galán, Carmen, Crespo, Luis, Iglesias Pérez, Antonio, González-Perez, Francisco Jesús, Morón, José Andrés, Moreno Nogueira, Luis Miguel, Real, Manuel Hidalgo, Pascual, Agustin, Ruiz, Jose Luis, Royo
Publikováno v: Medical science monitor : international medical journal of experimental and clinical research. 14(3)
Prolonged exposure to estrogens was found to be a risk factor for breast cancer. The molecular mechanism has been suggested to be the binding of estrogen receptors in mammary tissue, which promotes the proliferation of breast tissue. Different biomar
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::d6c8030cadb93ad7b312e634fe941c44
https://pubmed.ncbi.nlm.nih.gov/18301357
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6
Identification of a protective haplogenotype within CAPN10 gene influencing colorectal cancer susceptibility
Autor: Servando F Diez, Concha M Rey, Jose Luis Royo, Manuel Serrano-Ríos, Manuel Hidalgo Pascual, Carmen P Frances, Pablo P Torres, Luis Miguel Real, Juan Andres Ramírez-Armengol, Antonio González-Pérez, María Eugenia Sáez, Manuel Chaves Conde, José L G López, Agustín Ruiz
Publikováno v: Journal of gastroenterology and hepatology. 22(12)
Background and Aim: Colorectal cancer (CRC) is one of the most prevalent types of cancer affecting both men and women in developed countries. Clinical and molecular evidence suggests that there are multiple biochemical pathways involved in its suscep
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d48a8c2875292771a04366cdaa08a1c0
https://pubmed.ncbi.nlm.nih.gov/17559371
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7
Genetic analysis of caveolin-1 and eNOS genes in colorectal cancer
Autor: Eva Molero, Manuel Chaves Conde, Luis Miguel Real, Carlos García Martín-Cordova, Jose Miguel Esteban Lopez-Jamar, José Andrés Moreno Nogueira, Jose Luis Royo, Juan Andres Ramírez-Armengol, Manuel Hidalgo Pascual, Reposo Ramírez-Lorca, Agustín Ruiz
Publikováno v: Oncology reports. 16(2)
Journal Article; Research Support, Non-U.S. Gov't; Caveolae are involved in physical compartmentalization between different groups of signaling events. Its main component, CAV1, modulates different pathways in cellular physiology. The emerging eviden
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::414692acc4e828c16969a9ca88c12f25
https://pubmed.ncbi.nlm.nih.gov/16820915
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8
Pyrosequencing protocol requiring a unique biotinylated primer
Autor: Eduardo Ferrero Herrero, Francisco Jose Tello, Jose Luis Royo, Maria Del Carmen Rivero, Ana Salinas, Luis Miguel Real, Agustín Ruiz, Manuel Hidalgo Pascual
Publikováno v: Clinical chemistry and laboratory medicine. 44(4)
Background DNA sequencing has markedly changed the nature of biomedical research. Large-scale sequencing projects have generated several millions of potential polymorphisms widespread in the human genome requiring validation and incorporation into sc
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fdfad5ac473c0fefeea839c443f66515
https://pubmed.ncbi.nlm.nih.gov/16599838
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9
Exploring allelic imbalance within paraffin-embedded tumor biopsies using pyrosequencing technology
Autor: Reposo Ramírez-Lorca, Manuel Hidalgo Pascual, Jose Luis Royo, María Lopez-García, Francisco Jose Martínez-Tello, Eduardo Ferrero Herrero, Agustín Ruiz, Ana Salinas, Carmen Crespo, Luis Miguel Real
Publikováno v: Clinical Chemistry and Laboratory Medicine (CCLM). 44
Background: The comparison of molecular genetic changes in healthy and pathological tissues has historically led to the identification of oncogenes and tumor suppressor genes. It is very common that studies investigating loss of heterozygosity are ca
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9fb9b8d4686ae2ffe0b500099083fda0
https://doi.org/10.1515/cclm.2006.198
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