Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Manuel Halte"'
FlhE functions as a chaperone to prevent formation of periplasmic flagella in Gram-negative bacteria
Autor:
Manuel Halte, Ekaterina P. Andrianova, Christian Goosmann, Fabienne F. V. Chevance, Kelly T. Hughes, Igor B. Zhulin, Marc Erhardt
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract The bacterial flagellum, which facilitates motility, is composed of ~20 structural proteins organized into a long extracellular filament connected to a cytoplasmic rotor-stator complex via a periplasmic rod. Flagellum assembly is regulated b
Externí odkaz:
https://doaj.org/article/1fae30fb18c340a380f649d28be01a86
Publikováno v:
Journal of Biological Engineering, Vol 18, Iss 1, Pp 1-13 (2024)
Abstract Standardized and thoroughly characterized genetic tools are a prerequisite for studying cellular processes to ensure the reusability and consistency of experimental results. The discovery of fluorescent proteins (FPs) represents a milestone
Externí odkaz:
https://doaj.org/article/80ebdd4bb1d9418093f032e9dc8df56d
Autor:
Vanessa Muñoz-Gutierrez, Fabián A. Cornejo, Katja Schmidt, Christian K. Frese, Manuel Halte, Marc Erhardt, Alexander K. W. Elsholz, Kürşad Turgay, Emmanuelle Charpentier
Publikováno v:
mSystems, Vol 9, Iss 4 (2024)
ABSTRACTInitiation of bacterial DNA replication takes place at the origin of replication (oriC), a region characterized by the presence of multiple DnaA boxes that serve as the binding sites for the master initiator protein DnaA. This process is tigh
Externí odkaz:
https://doaj.org/article/c289fa04900e4f13b86da90c843c68c5
Autor:
Svenja Hüsing, Manuel Halte, Ulf van Look, Alina Guse, Eric J. C. Gálvez, Emmanuelle Charpentier, David F. Blair, Marc Erhardt, Thibaud T. Renault
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
Type-III secretion systems (T3SSs) are capable of translocating proteins with high speed while maintaining the membrane barrier for small molecules. Here, a structure-function analysis of the T3SS pore complex elucidates the precise mechanisms enabli
Externí odkaz:
https://doaj.org/article/b4b81677e4d248c0b18979bbe7b55964
Autor:
Manuel Halte, Marc Erhardt
Publikováno v:
Biomolecules, Vol 11, Iss 2, p 186 (2021)
The bacterial flagellum and the related virulence-associated injectisome system of pathogenic bacteria utilize a type III secretion system (T3SS) to export substrate proteins across the inner membrane in a proton motive force-dependent manner. The T3
Externí odkaz:
https://doaj.org/article/fae46916db554c53a69e1b4a93c76f2d
Autor:
Jessica A. Buttress, Manuel Halte, J. Derk te Winkel, Marc Erhardt, Philipp F. Popp, Henrik Strahl
Publikováno v:
Microbiology (Reading, England). 168(9)
Transmembrane potential is one of the main bioenergetic parameters of bacterial cells, and is directly involved in energizing key cellular processes such as transport, ATP synthesis and motility. The most common approach to measure membrane potential
Autor:
Vanessa Muñoz-Gutierrez, Fabián A. Cornejo, Katja Schmidt, Christian K. Frese, Manuel Halte, Marc Erhardt, Alexander K.W. Elsholz, Kürşad Turgay, Emmanuelle Charpentier
Initiation of bacterial DNA replication takes place at the origin of replication, a region characterized by the presence of multiple DnaA boxes that serve as the binding sites for the master initiator protein DnaA. The absence or failure of DNA repli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cc0b200bb544a9d8d8b705feca9bc138
https://doi.org/10.1101/2022.09.20.508806
https://doi.org/10.1101/2022.09.20.508806
The widespread bacterial second messenger bis-(3’-5’)-cyclic diguanosine monophosphate (c-di-GMP) is an important regulator of biofilm formation, virulence and cell differentiation. C-di-GMP-specific biosensors that allow detection and visualizat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e2a4bfcda6288262ab25ba3ea4a09948
https://doi.org/10.1101/2021.08.26.457767
https://doi.org/10.1101/2021.08.26.457767
Publikováno v:
Molecular Microbiology. 116(4):1189-1200
The assembly of the bacterial flagellum is orchestrated by the secretion of distinct early and late secretion substrates via the flagellar‐specific type‐III secretion system (fT3SS). However, how the fT3SS is able to distinguish between the diffe