Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Manuel Giménez-Andrés"'
Autor:
Boris Simonetti, Qian Guo, Manuel Giménez-Andrés, Kai-En Chen, Edmund R R Moody, Ashley J Evans, Mintu Chandra, Chris M Danson, Tom A Williams, Brett M Collins, Peter J Cullen
Publikováno v:
PLoS Biology, Vol 20, Iss 4, p e3001601 (2022)
Coat complexes coordinate cargo recognition through cargo adaptors with biogenesis of transport carriers during integral membrane protein trafficking. Here, we combine biochemical, structural, and cellular analyses to establish the mechanistic basis
Externí odkaz:
https://doaj.org/article/844881cd71af4ba98857830ac0cd310b
Autor:
Manuel Giménez-Andrés, Tadej Emeršič, Sandra Antoine-Bally, Juan Martin D'Ambrosio, Bruno Antonny, Jure Derganc, Alenka Čopič
Publikováno v:
eLife, Vol 10 (2021)
Numerous proteins target lipid droplets (LDs) through amphipathic helices (AHs). It is generally assumed that AHs insert bulky hydrophobic residues in packing defects at the LD surface. However, this model does not explain the targeting of perilipins
Externí odkaz:
https://doaj.org/article/feb96be726824530b92c9c9c35541f93
Autor:
Alenka Čopič, Sandra Antoine-Bally, Manuel Giménez-Andrés, César La Torre Garay, Bruno Antonny, Marco M. Manni, Sophie Pagnotta, Jeanne Guihot, Catherine L. Jackson
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-16 (2018)
Lipid droplets are cellular organelles important for cellular homeostasis and their disruption has been implicated in many diseases. Here the authors use a large amphipathic helix from perilipin 4 to uncover parameters important for specific lipid dr
Externí odkaz:
https://doaj.org/article/492f328f8d8144b1b134824fe07962c6
Publikováno v:
Biomolecules, Vol 8, Iss 3, p 45 (2018)
Amphipathic helices (AHs), a secondary feature found in many proteins, are defined by their structure and by the segregation of hydrophobic and polar residues between two faces of the helix. This segregation allows AHs to adsorb at polar–apolar int
Externí odkaz:
https://doaj.org/article/52784150ae0b48738d4cc6fcca07d547
Autor:
Boris Simonetti, Qian Guo, Manuel Giménez-Andrés, Kai-En Chen, Edmund R. R. Moody, Ashley J. Evans, Mintu Chandra, Chris M. Danson, Tom A. Williams, Brett M. Collins, Peter J. Cullen
Publikováno v:
Simonetti, B, Guo, Q, Gimenez Andres, M, Chen, K E, Moody, E R R, Evans, A J, Chandra, M, Danson, C M, Williams, T, Collins, B M & Cullen, P J 2022, ' SNX27–Retromer directly binds ESCPE-1 to transfer cargo proteins during endosomal recycling ', PLoS Biology, vol. 20, no. 4, e3001601 . https://doi.org/10.1371/journal.pbio.3001601
Coat complexes coordinate cargo recognition through cargo adaptors with biogenesis of transport carriers during integral membrane protein trafficking. Here, we combine biochemical, structural, and cellular analyses to establish the mechanistic basis
Autor:
Manuel Giménez Andrés, Marco M. Manni, Alenka Čopič, Catherine L. Jackson, Bruno Antonny, Sandra Antoine-Bally
Publikováno v:
Biophysical Journal. 114:276a