Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Manuel G. Ricardo"'
Autor:
Dayma Llanes, Robert Rennert, Paul Jänicke, Ibrahim Morgan, Leslie Reguera, Daniel G. Rivera, Manuel G. Ricardo, Ludger A. Wessjohann
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
Peptide-drug conjugates (PDCs) have recently gained significant attention for the targeted delivery of anticancer therapeutics, mainly due to their cost-effective and chemically defined production and lower antigenicity compared to ADCs, among other
Externí odkaz:
https://doaj.org/article/b88c4841469c42cf98f8f0c8103a7198
Autor:
Marlene C. S. Dal Colle, Manuel G. Ricardo, Nives Hribernik, José Danglad-Flores, Peter H. Seeberger, Martina Delbianco
Publikováno v:
Beilstein Journal of Organic Chemistry, Vol 19, Iss 1, Pp 1015-1020 (2023)
Automated glycan assembly (AGA) affords collections of well-defined glycans in a short amount of time. We systematically analyzed how parameters connected to the solid support affect the AGA outcome for three different glycan sequences. We showed tha
Externí odkaz:
https://doaj.org/article/38a83409005b429590dd4434f086a212
Publikováno v:
Chemistry (Weinheim an Der Bergstrasse, Germany)
Aetokthonotoxin has recently been identified as the cyanobacterial neurotoxin causing Vacuolar Myelinopathy, a fatal neurologic disease, spreading through a trophic cascade and affecting birds of prey such as the bald eagle in the USA. Here, we descr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48077cb89a05b6954b6faa105014626e
https://doi.org/10.1002/chem.202101848
https://doi.org/10.1002/chem.202101848
Autor:
Manuel G. Ricardo, Emelie E. Reuber, Ling Yao, José Danglad-Flores, Martina Delbianco, Peter H. Seeberger
Publikováno v:
Journal of the American Chemical Society
Stapling short peptides to lock specific conformations and thereby obtain superior pharmacological properties is well established. However, similar concepts have not been applied to oligosaccharides. Here, we describe the design, synthesis, and chara
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::033d3e65111c9074f68bb246870f48d4
https://hdl.handle.net/21.11116/0000-000B-32C1-221.11116/0000-000B-487D-9
https://hdl.handle.net/21.11116/0000-000B-32C1-221.11116/0000-000B-487D-9
Autor:
Manuel G. Ricardo, Celia G. Moya, Carlos S. Pérez, Andrea Porzel, Ludger A. Wessjohann, Daniel G. Rivera
Publikováno v:
Angewandte Chemie. 132:265-269
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ef5c1d134b771e3c3c878fe03e4b38b9
https://doi.org/10.1002/ange.201912095
https://doi.org/10.1002/ange.201912095
Publikováno v:
Methods in Molecular Biology ISBN: 9781071616888
Multicomponent reactions (MCRs) are recently expanding the plethora of solid-phase protocols for the synthesis and derivatization of peptides. Herein, we describe a solid-phase-compatible strategy based on MCRs as a powerful strategy for peptide cycl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::371a066476ac53fef43e4da22b8854c2
https://doi.org/10.1007/978-1-0716-1689-5_8
https://doi.org/10.1007/978-1-0716-1689-5_8
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2371
Multicomponent reactions (MCRs) are recently expanding the plethora of solid-phase protocols for the synthesis and derivatization of peptides. Herein, we describe a solid-phase-compatible strategy based on MCRs as a powerful strategy for peptide cycl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::594f7a65d9958014d33cb509babcbda6
https://pubmed.ncbi.nlm.nih.gov/34596847
https://pubmed.ncbi.nlm.nih.gov/34596847
Autor:
Enrique Noa, Ubel Ramirez, Tammy Boggiano, Luis Javier González, Gretchen Bergado, Vicente Verez-Bencomo, Laura Rodriguez, Yury Valdés-Balbín, Raine Garrido, Luis Ariel Espinosa, Yanet Climent, Rocmira Perez, Eduardo Ojito, Kalet León Monzón, Jean-Pierre Soubal, Sonsire Fernández, Daniel G. Rivera, Darielys Santana-Mederos, Felix Cardoso, Claudia Acosta, Lauren Quintero, Yanelys Cabrera Infante, Fabrizio Chiodo, Anamary Suarez, Sum Lai Losada, Tays Hernández, Reinaldo Oliva, Franciscary Pi, Manuel G. Ricardo, Belinda Sánchez Ramírez, Dagmar García-Rivera, Annet Valdes, Mario Landys, Cheng Fang, Yanira Méndez, Juliet Enriquez, Yassel Ramos, Humberto Gonzalez, Guang-Wu Chen, Ernesto Relova-Hernández, Tania Carmenate, Françoise Paquet, Gertrudis Rojas, Mildrey Farinas
Publikováno v:
ACS Chemical Biology
ACS Chemical Biology, American Chemical Society, 2021, 16 (7), pp.1223-1233. ⟨10.1021/acschembio.1c00272⟩
ACS Chemical Biology, American Chemical Society, 2021, 16 (7), pp.1223-1233. ⟨10.1021/acschembio.1c00272⟩
Controlling the global COVID-19 pandemic depends, among other measures, on developing preventive vaccines at an unprecedented pace. Vaccines approved for use and those in development intend to use neutralizing antibodies to block viral sites binding
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47ed20c7d44f94f684c5d3d1cfeb572b
https://pubmed.ncbi.nlm.nih.gov/34219448
https://pubmed.ncbi.nlm.nih.gov/34219448
Publikováno v:
Organic Letters. 21:7307-7310
A solid-phase approach including on-resin Ugi reactions was developed for the construction of β-hairpins. Various N-alkylated dipeptide fragments proved capable of aligning antiparallel β-sheets in...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::318e80185c8e95ca1e0f1bad4feb2da2
https://doi.org/10.1021/acs.orglett.9b02592
https://doi.org/10.1021/acs.orglett.9b02592
Publikováno v:
Angewandte Chemie. 131:2726-2730
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7a0cadc6786057164532243f9fc0f587
https://doi.org/10.1002/ange.201812620
https://doi.org/10.1002/ange.201812620