Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Manuel G. Afable"'
Autor:
Manuel G. Afable, Mohammed Shaik, Yuka Sugimoto, Paul Elson, Michael Clemente, Hideki Makishima, Mikkael A. Sekeres, Alan Lichtin, Anjali Advani, Matt Kalaycio, Ramon V. Tiu, Christine L. O’Keefe, Jaroslaw P. Maciejewski
Publikováno v:
Haematologica, Vol 96, Iss 9 (2011)
Background A combination of horse anti-thymocyte globulin and cyclosporine produces responses in 60–70% of patients with severe aplastic anemia. We performed a phase II study of rabbit anti-thymocyte globulin and cyclosporine as first-line therapy
Externí odkaz:
https://doaj.org/article/7c26f0276b1e4d5c802c5ea75f3f6f44
Autor:
Peter Chomczynski, Mikkael A. Sekeres, Alan E. Lichtin, John Desamito, Cassandra M. Hirsch, Tomas Radivoyevitch, Srinivasa R. Sanikommu, Brad Pohlman, Manuel G. Afable, Swapna Thota, Bhumika J. Patel, Jaroslaw P. Maciejewski, Aziz Nazha, Michael J. Clemente, Andres Jerez
Publikováno v:
Leuk Lymphoma
Large granular lymphocytic leukemia (LGLL) represents a clonal/oligoclonal lymphoproliferation of cytotoxic T and natural killer cells often associated with STAT3 mutations. When symptomatic, due to mostly anemia and neutropenia, therapy choices are
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8f965a7bbc6d0b5750d00e578151b0a
https://doi.org/10.1080/10428194.2017.1339880
https://doi.org/10.1080/10428194.2017.1339880
Autor:
Austin G. Kulasekararaj, Satu Mustjoki, Bartlomiej P Przychodzen, Hanna Rajala, Catherine Nissen, Sonja Lagström, Inés Gómez-Seguí, Dan Zhang, Thomas P. Loughran, Holleh D Husseinzadeh, Andres Jerez, Thomas L. Olson, Aleksandra Wodnar-Filipowicz, Manuel G. Afable, Alan F. List, Michael J. Clemente, Pekka Ellonen, Ghulam J. Mufti, Naoko Hosono, Francis R LeBlanc, Alan E. Lichtin, Hideki Makishima, Kathy L. McGraw, Jaroslaw P. Maciejewski, André Tichelli
Publikováno v:
Blood. 122:2453-2459
Large granular lymphocyte leukemia (LGL) is often associated with immune cytopenias and can cooccur in the context of aplastic anemia (AA) and myelodysplastic syndromes (MDS). We took advantage of the recent description of signal transducer and activ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75a00f1d4dc3ddeb693b93b10ef6c0fe
https://doi.org/10.1182/blood-2013-04-494930
https://doi.org/10.1182/blood-2013-04-494930
Autor:
Edy Hasrouni, Ali Tabarroki, Heesun J. Rogers, Mikkael A. Sekeres, Valeria Visconte, Manuel G. Afable, Ramon V. Tiu, Jaroslaw P. Maciejewski, Fabiola Traina
Publikováno v:
SAGE Open Medical Case Reports
SAGE Open Medical Case Reports, Vol 1 (2013)
SAGE Open Medical Case Reports, Vol 1 (2013)
Introduction: Autoimmune myelofibrosis is an uncommon hematologic disease characterized by anemia, bone marrow myelofibrosis, and an autoimmune feature. Myelofibrosis is often associated with other conditions, including infections, nutritional/endocr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aef9f3c7a20af4243649cf334e380fd0
https://pubmed.ncbi.nlm.nih.gov/27489629
https://pubmed.ncbi.nlm.nih.gov/27489629
Autor:
Kathy L. McGraw, Satu Mustjoki, Mikkael A. Sekeres, Hideki Makishima, Thomas L. Olson, Eric D. Hsi, Andres Jerez, Lisa Durkin, Bartlomiej P Przychodzen, Hanna Koskela, Kathryn M Guinta, Marcin W. Wlodarski, Manuel G. Afable, Michael J. Clemente, Kwok Peng Ng, Francis R LeBlanc, Dan Zhang, Thomas P. Loughran, Alan F. List, Jaroslaw P. Maciejewski, Kimmo Porkka, Inés Gómez-Seguí
Publikováno v:
Blood. 120:3048-3057
Chronic lymphoproliferative disorders of natural killer cells (CLPD-NKs) and T-cell large granular lymphocytic leukemias (T-LGLs) are clonal lymphoproliferations arising from either natural killer cells or cytotoxic T lymphocytes (CTLs). We have inve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e909607d859a75a03cd8999bbfba449
https://doi.org/10.1182/blood-2012-06-435297
https://doi.org/10.1182/blood-2012-06-435297
Autor:
Anjali S. Advani, Mikkael A. Sekeres, Ronald Sobecks, Jaroslaw P. Maciejewski, Harry P. Erba, Josephine Chan, Manuel G. Afable, Sherry Seel, Matt Kalaycio, Ricki Englehaupt
Publikováno v:
Cancer. 117:1253-1261
BACKGROUND: Higher-risk myelodysplastic syndromes (MDS) are similar pathobiologically to acute myeloid leukemia (AML), particularly in older adults. AML therapies thus may have activity in MDS. In the current study, phase 2 study data of arsenic trio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0be00db99d39c132a8fd1f251dd6cd84
https://doi.org/10.1002/cncr.25686
https://doi.org/10.1002/cncr.25686
Autor:
Rebecca D. Ganetzky, Hadrian Szpurka, Jungwon Huh, Hideki Makishima, Anna M. Jankowska, Christine L. O'Keefe, Manuel G. Afable, Michael A. McDevitt, Jaroslaw P. Maciejewski, Ramon V. Tiu
Publikováno v:
Blood. 113:6403-6410
Chromosomal abnormalities are frequent in myeloid malignancies, but in most cases of myelodysplasia (MDS) and myeloproliferative neoplasms (MPN), underlying pathogenic molecular lesions are unknown. We identified recurrent areas of somatic copy numbe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa9056c0cd2d07f2c42bf732217e13ba
https://doi.org/10.1182/blood-2009-02-205690
https://doi.org/10.1182/blood-2009-02-205690
Autor:
Debra E. Lyon, Manuel G. Afable
Publikováno v:
Clinical Journal of Oncology Nursing. 12:569-573
Mr. X, a single, 55-year-old administrative assistant, presented to his family practice clinic with a complaint of fatigue. He was previously healthy and enjoyed walking his dog in his free time. Mr. X reported that he was easily fatigued and often s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90ba3d5e5c0cc6ec52efce50ed8abafc
https://doi.org/10.1188/08.cjon.569-573
https://doi.org/10.1188/08.cjon.569-573
Autor:
Brittney Dienes, Satu Mustjoki, Hanna Rajala, Michael J. Clemente, Holleh D Husseinzadeh, Bartlomiej P Przychodzen, Marcin W. Wlodarski, Manuel G. Afable, Jaroslaw P. Maciejewski, Andres Jerez
Publikováno v:
Blood. 122(25)
New massively parallel sequencing technology enables, through deep sequencing of rearranged T-cell receptor (TCR) Vβ complementarity-determining region 3 (CDR3) regions, a previously inaccessible level of TCR repertoire analysis. The CDR3 repertoire
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5e00943efb6bf066890c2fba59b0dc3
https://pubmed.ncbi.nlm.nih.gov/24149287
https://pubmed.ncbi.nlm.nih.gov/24149287
Autor:
Ricki Englehaupt, Andres Jerez, Alan F. List, Rami S. Komrokji, Jeffrey E. Lancet, David Cuthbertson, Ali Tabarroki, Hideki Makishima, Anjali S. Advani, Ronald Paquette, Joyce Juersivich, Manuel G. Afable, Jaroslaw P. Maciejewski, Mikkael A. Sekeres, Valeria Visconte, Ramon V. Tiu, Jennifer Paleveda
Publikováno v:
Blood. 120(25)
Lenalidomide and azacitidine each have activity in myelodysplastic syndromes (MDS) patients, where both microenvironment and cell-regulatory mechanisms contribute to disease pathogenesis. The objective of this multicenter, phase 2 expansion trial was
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89bdda1a82a984ba6a4f2fc1a3026355
https://pubmed.ncbi.nlm.nih.gov/23373778
https://pubmed.ncbi.nlm.nih.gov/23373778