Interaction of HIV-1 Gag with the clathrin-associated adaptor AP-2

Autor: Paul Spearman, Stefan Höning, Manuel Favre, Michael Boge, Melissa Batonick, Markus Thali

Publikováno v: Virology. 342:190-200

The envelope glycoprotein (Env) of HIV-1 interacts with the clathrin-associated adaptor complex AP-2 during the late phase of the viral replication cycle. Upon its synthesis, Env, therefore, is retrieved from the cellular surface unless internalizati

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fcc987f97c6e97229965cb89bc404215
https://doi.org/10.1016/j.virol.2005.08.001

Molecular and therapeutic characterization of anti- Ectodysplasin A receptor (EDAR) agonist monoclonal antibodies

Autor: Olivier Gaide, Pascal Schneider, Manuel Favre, Nathalie Dunkel, Margret L. Casal, Stéphane Demotz, Elizabeth A. Mauldin, Douglas M. Jefferson, Laure Willen, Denis J. Headon, Aubry Tardivel, Giovanna Badic, Christine Kowalczyk, Anne-Lise Etter

Publikováno v: Kowalczyk, C, Dunkel, N, Willen, L, Casal, M L, Mauldin, E A, Gaide, O, Tardivel, A, Badic, G, Etter, A L, Favre, M, Jefferson, D M, Headon, D J, Demotz, S & Schneider, P 2011, ' Molecular and therapeutic characterization of anti-Ectodysplasin A receptor (EDAR) agonist monoclonal antibodies ', Journal of Biological Chemistry, vol. 286, no. 35, pp. 30769-30779 . https://doi.org/10.1074/jbc.M111.267997
The Journal of biological chemistry
J Biol Chem
Journal of Biological Chemistry, vol. 286, no. 35, pp. 30769-30779

The TNF family ligand ectodysplasin A (EDA) and its receptor EDAR are required for proper development of skin appendages such as hair, teeth, and eccrine sweat glands. Loss of function mutations in the Eda gene cause X-linked hypohidrotic ectodermal

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::006500d04c38113fcbadae64e5a51d9b
https://hdl.handle.net/20.500.11820/c3330bd7-d68a-4edc-90f5-db9d4b40268a

Interactions of processed Nef (58-206) with virion proteins of HIV type 1

Autor: Gabriela Bleiber, Manuel Favre, Angela Ciuffi, Amalio Telenti, Françoise Stutz, Pascal Meylan, Miguel Munoz

Publikováno v: AIDS Research and Human Retroviruses, vol. 20, no. 4, pp. 399-407
AIDS Research and Human Retroviruses, Vol. 20, No 4 (2004) pp. 399-407

The Nef protein plays a major role in vivo in promoting HIV and SIV replication and pathogenesis. In vitro, Nef has been shown to down-regulate cell surface molecules, such as CD4 and MHC-I, alter T cell signaling, and enhance virion infectivity. The

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f7fdfb675695120f6ba699f2ad662be
https://serval.unil.ch/resource/serval:BIB_43A333F54B1C.P001/REF.pdf