Zobrazeno 1 - 10
of 101
pro vyhledávání: '"Manuel Dauchez"'
Publikováno v:
Frontiers in Bioinformatics, Vol 4 (2024)
Advances in simulations, combined with technological developments in high-performance computing, have made it possible to produce a physically accurate dynamic representation of complex biological systems involving millions to billions of atoms over
Externí odkaz:
https://doaj.org/article/d71bd7d1f5704880bb66652f7e9fb870
Autor:
Azzam Alwan, Remi Cogranne, Pierre Beauseroy, Edith Grall-Maes, Nicolas Belloy, Laurent Debelle, Stephanie Baud, Manuel Dauchez, Sebastien Almagro
Publikováno v:
IEEE Access, Vol 9, Pp 92143-92156 (2021)
Over the past decades, the understanding of peptides and proteins biological functions has been an active research topic. Latest research works in this field have suggested that protein conformations may be a key feature for gaining insights into pro
Externí odkaz:
https://doaj.org/article/67b6802432f44a2b8774289c3bc36cd3
Autor:
Hua Wong, Jean-Marc Crowet, Manuel Dauchez, Sylvie Ricard-Blum, Stéphanie Baud, Nicolas Belloy
Publikováno v:
Matrix Biology Plus, Vol 13, Iss , Pp 100096- (2022)
The extracellular matrix is a complex three-dimensional network of molecules that provides cells with a complex microenvironment. The major constituents of the extracellular matrix such as collagen, elastin and associated proteins form supramolecular
Externí odkaz:
https://doaj.org/article/84846044ba1c41bea0c497e4f92e49a0
Publikováno v:
ACS Omega, Vol 4, Iss 5, Pp 8495-8505 (2019)
Externí odkaz:
https://doaj.org/article/3c5e1f3281054ce285e9ad4c5d1fa819
Autor:
Camille Albrecht, Andrey S. Kuznetsov, Aline Appert-Collin, Zineb Dhaideh, Maïté Callewaert, Yaroslav V. Bershatsky, Anatoly S. Urban, Eduard V. Bocharov, Dominique Bagnard, Stéphanie Baud, Sébastien Blaise, Béatrice Romier-Crouzet, Roman G. Efremov, Manuel Dauchez, Laurent Duca, Marc Gueroult, Pascal Maurice, Amar Bennasroune
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 8 (2020)
Sialidases, or neuraminidases, are involved in several human disorders such as neurodegenerative, infectious and cardiovascular diseases, and cancers. Accumulative data have shown that inhibition of neuraminidases, such as NEU1 sialidase, may be a pr
Externí odkaz:
https://doaj.org/article/07a99ce083d34a60866086896cbe236a
Autor:
Aïcha Ben Zemzem, Xiaowen Liang, Laetitia Vanalderwiert, Camille Bour, Béatrice Romier-Crouzet, Sébastien Blaise, Michael J. Sherratt, Timm Weitkamp, Manuel Dauchez, Stéphanie Baud, Nicolas Passat, Laurent Debelle, Sébastien Almagro
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 6, p 3250 (2022)
Diabetes is a major concern of our society as it affects one person out of 11 around the world. Elastic fiber alterations due to diabetes increase the stiffness of large arteries, but the structural effects of these alterations are poorly known. To a
Externí odkaz:
https://doaj.org/article/28a8d164267447cdb74f933e8ed65d67
Autor:
Eléonore Lambert, Eloïse Fuselier, Laurent Ramont, Bertrand Brassart, Sylvain Dukic, Jean-Baptiste Oudart, Aurélie Dupont-Deshorgue, Christèle Sellier, Carine Machado, Manuel Dauchez, Jean-Claude Monboisse, François-Xavier Maquart, Stéphanie Baud, Sylvie Brassart-Pasco
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-13 (2018)
Abstract Tetrastatin, a 230 amino acid sequence from collagen IV, was previously demonstrated to inhibit melanoma progression. In the present paper, we identified the minimal active sequence (QKISRCQVCVKYS: QS-13) that reproduced the anti-tumor effec
Externí odkaz:
https://doaj.org/article/b13252cfd5e842f7aba5081827f0d566
Autor:
Pierre Darme, Manuel Dauchez, Arnaud Renard, Laurence Voutquenne-Nazabadioko, Dominique Aubert, Sandie Escotte-Binet, Jean-Hugues Renault, Isabelle Villena, Luiz-Angelo Steffenel, Stéphanie Baud
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 14, p 7489 (2021)
Molecular docking is widely used in computed drug discovery and biological target identification, but getting fast results can be tedious and often requires supercomputing solutions. AMIDE stands for AutoMated Inverse Docking Engine. It was initially
Externí odkaz:
https://doaj.org/article/2a67e0691bc845e19cda5af3c2e65d79
Autor:
Laurie Verzeaux, Nicolas Belloy, Jessica Thevenard-Devy, Jérôme Devy, Géraldine Ferracci, Laurent Martiny, Stéphane Dedieu, Manuel Dauchez, Hervé Emonard, Nicolas Etique, Emmanuelle Devarenne-Charpentier
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-14 (2017)
Abstract The tissue inhibitor of metalloproteinases-1 (TIMP-1) exerts inhibitory activity against matrix metalloproteinases and cytokine-like effects. We previously showed that TIMP-1 reduces neurite outgrowth in mouse cortical neurons and that this
Externí odkaz:
https://doaj.org/article/16e3c09a1b4d4103a912523a3d0bd5d9
Publikováno v:
ACS Omega, Vol 5, Iss 23, Pp 14202-14202 (2020)
Externí odkaz:
https://doaj.org/article/cbb210c7a22e48a4a3b311cf1f3af1f6