Zobrazeno 1 - 10
of 48
pro vyhledávání: '"Manuel Caruso"'
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Humanity did surprisingly well so far, considering how unprepared it was to respond to the coronavirus disease 2019 (COVID-19) threat. By blending old and ingenious new technology in the context of the accumulated knowledge on other human coronavirus
Externí odkaz:
https://doaj.org/article/0412d67cdc754176942c1125b4d9d199
Autor:
Sara L. Banerjee, Frédéric Lessard, François J.M. Chartier, Kévin Jacquet, Ana I. Osornio-Hernandez, Valentine Teyssier, Karim Ghani, Noémie Lavoie, Josée N. Lavoie, Manuel Caruso, Patrick Laprise, Sabine Elowe, Jean-Philippe Lambert, Nicolas Bisson
Publikováno v:
Cell Reports, Vol 40, Iss 1, Pp 111031- (2022)
Summary: EPH receptors (EPHRs) constitute the largest family among receptor tyrosine kinases in humans. They are mainly involved in short-range cell-cell communication events that regulate cell adhesion, migration, and boundary formation. However, th
Externí odkaz:
https://doaj.org/article/8fd2c903558b408894f403b0c0bd57f6
Publikováno v:
PLoS ONE, Vol 5, Iss 12, p e15753 (2010)
Diphtheria toxin (DT), Pseudomonas aeruginosa Exotoxin A (ETA) and cholix toxin from Vibrio cholerae share the same mechanism of toxicity; these enzymes ADP-rybosylate elongation factor-2 (EF-2) on a modified histidine residue called diphthamide, lea
Externí odkaz:
https://doaj.org/article/edce4651ac694e24a7338d68ae22dfba
Autor:
Martin A, Barbier, Angela Dakiw, Piaceski, Danielle, Larouche, Sarah H, Villeneuve, Karim, Ghani, Elena, Pope, Manuel, Caruso, Lucie, Germain
Publikováno v:
Current Protocols. 2
Efficient gene transfer into cultured fibroblasts and keratinocytes during retroviral transduction is a critical step toward the treatment of genodermatoses such as epidermolysis bullosa. However, achieving high transduction rates is still a difficul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44e5013f6779118d5dafb5e12799911b
https://doi.org/10.1002/cpz1.353
https://doi.org/10.1002/cpz1.353
Autor:
Michael Boivin-Welch, Elena Pope, Sylvie Roy, Lucie Germain, Karim Ghani, Manuel Caruso, Angela Dakiw-Piaceski, Martin A Barbier
Publikováno v:
Molecular Therapy. Methods & Clinical Development
The γ-retroviral vector is a gene delivery vehicle that is commonly used in gene therapy. Despite its efficacy, its strong enhancers contributed to malignant transformations in some hematopoietic stem cell (HSC) gene therapy trials. A safer version
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f850a439bc3e8d81044170b563cd86e
https://doi.org/10.1016/j.omtm.2019.05.013
https://doi.org/10.1016/j.omtm.2019.05.013
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) outbreak that started in China at the end of 2019 has rapidly spread to become pandemic. Several investigational vaccines that have already been tested in animals and humans were able t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::033859035ae5b7d8142cb998adde3aa7
https://doi.org/10.1101/2020.09.16.298992
https://doi.org/10.1101/2020.09.16.298992
Peel Test to Assess the Adhesion Strength of the Dermal-Epidermal Junction in Tissue-Engineered Skin
Autor:
Alex E Larose, Lucie Germain, Manuel Caruso, Elena Pope, Danielle Larouche, Robert Gauvin, Angela Dakiw-Piaceski, Martin A Barbier
Publikováno v:
Tissue engineering. Part C, Methods. 26(3)
Innovative therapies combining gene-corrected stem cells and the production of bioengineered tissues to treat epidermolysis bullosa are emerging. However, quantitative tests to measure the adhesion forces between two highly viscoelastic substrates su
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bba4dcf8f507b9f26a873228bb7ea979
https://pubmed.ncbi.nlm.nih.gov/32085694
https://pubmed.ncbi.nlm.nih.gov/32085694
Publikováno v:
Journal of Biological Chemistry. 288:24948-24955
Aliphatic n-alkanols are a family of ubiquitous substances that display general anesthetic properties in accordance to their degree of hydrophobicity. In addition, the immunomodulatory activity of one of its members, ethanol, has long been recognized
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4195d216a31b5ab7330bd2c62017517
https://doi.org/10.1074/jbc.m113.466334
https://doi.org/10.1074/jbc.m113.466334
Publikováno v:
Leukemia Research. 36:1311-1314
The tyrosine kinase inhibitor (TKI) imatinib has been used for a decade to treat chronic myeloid leukemia (CML). A very efficient response is obtained with patients in chronic phase, but its efficacy in late phase patients is often transient. The com
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a002f31bb21fcd9898e8d294b08c5f6
https://doi.org/10.1016/j.leukres.2012.06.012
https://doi.org/10.1016/j.leukres.2012.06.012