Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Manuel Cantu Gutierrez"'
Autor:
Connor Leek, Abiud Cantu, Shilpa Sonti, Manuel Cantu Gutierrez, Laurie Eldredge, Eniko Sajti, He N. Xu, Krithika Lingappan
Publikováno v:
Redox Biology, Vol 75, Iss , Pp 103296- (2024)
The lung macrophages play a crucial role in health and disease. Sexual dimorphism significantly impacts the phenotype and function of tissue-resident macrophages. The primary mechanisms responsible for sexually dimorphic outcomes in bronchopulmonary
Externí odkaz:
https://doaj.org/article/61d7856613d346e6afb2dbc5bfa6ac0b
Autor:
Sandra L. Grimm, Samuel Reddick, Xiaoyu Dong, Connor Leek, Amy Xiao Wang, Manuel Cantu Gutierrez, Sean M. Hartig, Bhagavatula Moorthy, Cristian Coarfa, Krithika Lingappan
Publikováno v:
Biology of Sex Differences, Vol 14, Iss 1, Pp 1-17 (2023)
Abstract Background Bronchopulmonary dysplasia (BPD) is characterized by an arrest in lung development and is a leading cause of morbidity in premature neonates. It has been well documented that BPD disproportionally affects males compared to females
Externí odkaz:
https://doaj.org/article/b08c6f1bdb5049889cfae7c8a2b0788f
Autor:
Abiud Cantu, Manuel Cantu Gutierrez, Xiaoyu Dong, Connor Leek, Montserrat Anguera, Krithika Lingappan
Publikováno v:
Redox Biology, Vol 68, Iss , Pp 102933- (2023)
Recovery from lung injury during the neonatal period requires the orchestration of many biological pathways. The modulation of such pathways can drive the developing lung towards proper repair or persistent maldevelopment that can lead to a disease p
Externí odkaz:
https://doaj.org/article/30374b43c768492ba4fc9d6462e48c6d
Autor:
Abiud Cantu Gutierrez, Manuel Cantu Gutierrez, Alexander M Rhyner, Oscar E Ruiz, George T Eisenhoffer, Joshua D Wythe
Publikováno v:
PLoS Biology, Vol 17, Iss 6, p e3000343 (2019)
The zebrafish Danio rerio is a powerful model system to study the genetics of development and disease. However, maintenance of zebrafish husbandry records is both time intensive and laborious, and a standardized way to manage and track the large amou
Externí odkaz:
https://doaj.org/article/81f17d17588c431fac22098eb2455dc4
Autor:
Sonal Nagarkar-Jaiswal, Pei-Tseng Lee, Megan E Campbell, Kuchuan Chen, Stephanie Anguiano-Zarate, Manuel Cantu Gutierrez, Theodore Busby, Wen-Wen Lin, Yuchun He, Karen L Schulze, Benjamin W Booth, Martha Evans-Holm, Koen JT Venken, Robert W Levis, Allan C Spradling, Roger A Hoskins, Hugo J Bellen
Publikováno v:
eLife, Vol 4 (2015)
Here, we document a collection of ∼7434 MiMIC (Minos Mediated Integration Cassette) insertions of which 2854 are inserted in coding introns. They allowed us to create a library of 400 GFP-tagged genes. We show that 72% of internally tagged proteins
Externí odkaz:
https://doaj.org/article/a360211c69524b5c898cb3e9e9faee55
Autor:
Joshua D. Wythe, Sameer S. Bajikar, Harini P. Tirumala, Yingyao Shao, Manuel Cantu Gutierrez, Huda Y. Zoghbi
Publikováno v:
Genes & Development. 35:489-494
While changes in MeCP2 dosage cause Rett syndrome (RTT) and MECP2 duplication syndrome (MDS), its transcriptional regulation is poorly understood. Here, we identified six putative noncoding regulatory elements of Mecp2, two of which are conserved in
Autor:
Benjamin Deneen, Jeffrey C. Carlson, Chad J. Creighton, Brittney Lozzi, Alexander M. Herman, Emmet Huang-Hobbs, Williamson D Turner, Manuel Cantu Gutierrez, Burak Tepe, Joshua D. Wythe, Ganesh Rao, Yiqun Zhang
Publikováno v:
Neuro Oncol
BackgroundGlioblastoma is the most common and aggressive type of primary brain tumor, as most patients succumb to the disease less than two years after diagnosis. Critically, studies demonstrate that glioma recruits surrounding blood vessels, while s
Autor:
Meng Cui, Emilie Boudreau, Alexander M. Herman, Dakota Gustafson, Ivan Radovanovic, Jason E. Fish, Karen Berman de Ruiz, Zhiqi Chen, Joshua D. Wythe, Taylor S Schexnayder, Peter V. DiStefano, Manuel Cantu Gutierrez, Carlos Perfecto Flores-Suarez, Christopher S. Ward
Publikováno v:
Circulation Research. 127:727-743
Rationale: We previously identified somatic activating mutations in the KRAS ( Kirsten rat sarcoma viral oncogene homologue ) gene in the endothelium of the majority of human sporadic brain arteriovenous malformations; a disorder characterized by dir
Significant phenotypic differences exist between the vascular endothelium of different organs, including cell-cell junctions, paracellular fluid transport, shape, and mural cell coverage. These organ-specific morphological features ultimately manifes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3eded4843ec74f59ce8fa2cbec70eff2
https://doi.org/10.1101/2021.11.15.468651
https://doi.org/10.1101/2021.11.15.468651
Autor:
Sean P Marrelli, Gab Seok Kim, Jessica M. Stephenson, Manuel Cantu Gutierrez, Ting Wu, Joshua D. Wythe
Publikováno v:
Stroke. 52
Microglial cells (MG) serve as resident immune cells in the brain and play a critical role in the acute response and chronic recovery to stroke. However, how the transcriptional signature of these cells is altered in aging and stroke remains poorly d