Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Manuel Bernal-Llinares"'
Autor:
Susan A. Kennedy, Mohamed-Ali Jarboui, Sriganesh Srihari, Cinzia Raso, Kenneth Bryan, Layal Dernayka, Theodosia Charitou, Manuel Bernal-Llinares, Carlos Herrera-Montavez, Aleksandar Krstic, David Matallanas, Max Kotlyar, Igor Jurisica, Jasna Curak, Victoria Wong, Igor Stagljar, Thierry LeBihan, Lisa Imrie, Priyanka Pillai, Miriam A. Lynn, Erik Fasterius, Cristina Al-Khalili Szigyarto, James Breen, Christina Kiel, Luis Serrano, Nora Rauch, Oleksii Rukhlenko, Boris N. Kholodenko, Luis F. Iglesias-Martinez, Colm J. Ryan, Ruth Pilkington, Patrizia Cammareri, Owen Sansom, Steven Shave, Manfred Auer, Nicola Horn, Franziska Klose, Marius Ueffing, Karsten Boldt, David J. Lynn, Walter Kolch
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
Kras is often mutated in colorectal cancer but how this oncogenic mutation alters signalling pathways globally is undetermined. Here, the authors analyse how this mutation affects protein interaction networks and signal flow showing an extensive re
Externí odkaz:
https://doaj.org/article/9d3d9f430d2e481298f1f134583ff8b6
Autor:
Tanja Muetze, Ivan H. Goenawan, Heather L. Wiencko, Manuel Bernal-Llinares, Kenneth Bryan, David J. Lynn
Publikováno v:
F1000Research, Vol 5 (2016)
Highly connected nodes (hubs) in biological networks are topologically important to the structure of the network and have also been shown to be preferentially associated with a range of phenotypes of interest. The relative importance of a hub node, h
Externí odkaz:
https://doaj.org/article/033b21814a164ad2a1650b751c4c906a
Autor:
David Ochoa, Andrew Hercules, Miguel Carmona, Daniel Suveges, Jarrod Baker, Cinzia Malangone, Irene Lopez, Alfredo Miranda, Carlos Cruz-Castillo, Luca Fumis, Manuel Bernal-Llinares, Kirill Tsukanov, Helena Cornu, Konstantinos Tsirigos, Olesya Razuvayevskaya, Annalisa Buniello, Jeremy Schwartzentruber, Mohd Karim, Bruno Ariano, Ricardo Esteban Martinez Osorio, Javier Ferrer, Xiangyu Ge, Sandra Machlitt-Northen, Asier Gonzalez-Uriarte, Shyamasree Saha, Santosh Tirunagari, Chintan Mehta, Juan María Roldán-Romero, Stuart Horswell, Sarah Young, Maya Ghoussaini, David G Hulcoop, Ian Dunham, Ellen M McDonagh
Publikováno v:
Nucleic Acids Research. 51:D1353-D1359
The Open Targets Platform (https://platform.opentargets.org/) is an open source resource to systematically assist drug target identification and prioritisation using publicly available data. Since our last update, we have reimagined, redesigned, and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3dffeff31dcc4de4b454719a05269273
https://doi.org/10.1093/nar/gkac1046
https://doi.org/10.1093/nar/gkac1046
Autor:
Max Kotlyar, Priyanka Pillai, Theodosia Charitou, David Matallanas, Victoria Wong, Cinzia Raso, Luis F. Iglesias-Martinez, Colm J. Ryan, Steven Shave, Carlos Herrera-Montavez, Nicola Horn, Ruth Pilkington, Christina Kiel, Layal Dernayka, Miriam A. Lynn, Igor Jurisica, Manuel Bernal-Llinares, Lisa Imrie, Nora Rauch, Franziska Klose, Owen J. Sansom, David J. Lynn, Sriganesh Srihari, Marius Ueffing, Karsten Boldt, Luis Serrano, James Breen, Aleksandar Krstic, Erik Fasterius, Igor Stagljar, Kenneth Bryan, Mohamed Ali Jarboui, Thierry LeBihan, Boris N. Kholodenko, Oleksii S. Rukhlenko, Jasna Curak, Susan Kennedy, Manfred Auer, Cristina Al-Khalili Szigyarto, Walter Kolch, Patrizia Cammareri
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
Nature Communications
Kennedy, S A, Jarboui, M, Srihari, S, Raso, C, Bryan, K, Dernayka, L, Charitou, T, Bernal-llinares, M, Herrera-montavez, C, Krstic, A, Matallanas, D, Kotlyar, M, Jurisica, I, Curak, J, Wong, V, Stagljar, I, Lebihan, T, Imrie, L, Pillai, P, Lynn, M A, Fasterius, E, Al-khalili Szigyarto, C, Breen, J, Kiel, C, Serrano, L, Rauch, N, Rukhlenko, O, Kholodenko, B N, Iglesias-martinez, L F, Ryan, C J, Pilkington, R, Cammareri, P, Sansom, O, Shave, S, Auer, M, Horn, N, Klose, F, Ueffing, M, Boldt, K, Lynn, D J & Kolch, W 2020, ' Extensive rewiring of the EGFR network in colorectal cancer cells expressing transforming levels of KRASG13D ', Nature Communications, vol. 11, no. 1 . https://doi.org/10.1038/s41467-019-14224-9
nature.com
Nature Communications
Kennedy, S A, Jarboui, M, Srihari, S, Raso, C, Bryan, K, Dernayka, L, Charitou, T, Bernal-llinares, M, Herrera-montavez, C, Krstic, A, Matallanas, D, Kotlyar, M, Jurisica, I, Curak, J, Wong, V, Stagljar, I, Lebihan, T, Imrie, L, Pillai, P, Lynn, M A, Fasterius, E, Al-khalili Szigyarto, C, Breen, J, Kiel, C, Serrano, L, Rauch, N, Rukhlenko, O, Kholodenko, B N, Iglesias-martinez, L F, Ryan, C J, Pilkington, R, Cammareri, P, Sansom, O, Shave, S, Auer, M, Horn, N, Klose, F, Ueffing, M, Boldt, K, Lynn, D J & Kolch, W 2020, ' Extensive rewiring of the EGFR network in colorectal cancer cells expressing transforming levels of KRASG13D ', Nature Communications, vol. 11, no. 1 . https://doi.org/10.1038/s41467-019-14224-9
nature.com
Protein-protein-interaction networks (PPINs) organize fundamental biological processes, but how oncogenic mutations impact these interactions and their functions at a network-level scale is poorly understood. Here, we analyze how a common oncogenic K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc319b683485723bed6ff60ef6bb1dac
http://link.springer.com/article/10.1038/s41467-019-14224-9
http://link.springer.com/article/10.1038/s41467-019-14224-9
Autor:
Christine Ferguson, Simon Lambert, Manuel Bernal Llinares, Frances Madden, Robin Dasler, Martin Fenner, Artemis Lavasa, Chris Baars, Tina Dohna, Ketil Koop-Jacobsen, Dan Morgan
This deliverable demonstrates how the various partners in FREYA are taking up persistent identifiers for organizations as part of the Work Package 4 work on integrating emerging PID types into disciplinary contexts. A range of organization IDs are di
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3519ae407c38c2344d962544856881c7
Autor:
Henning Hermjakob, Javier Ferrer-Gómez, Manuel Bernal-Llinares, Sarala M. Wimalaratne, Carole Goble, Nick Juty
Publikováno v:
Bioinformatics
Motivation Since its launch in 2010, Identifiers.org has become an important tool for the annotation and cross-referencing of Life Science data. In 2016, we established the Compact Identifier (CID) scheme (prefix: accession) to generate globally uniq
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::705e0b721e3090b33c03b9bd6b3f802d
https://doi.org/10.1093/bioinformatics/btaa864
https://doi.org/10.1093/bioinformatics/btaa864
Autor:
Susan A, Kennedy, Mohamed-Ali, Jarboui, Sriganesh, Srihari, Cinzia, Raso, Kenneth, Bryan, Layal, Dernayka, Theodosia, Charitou, Manuel, Bernal-Llinares, Carlos, Herrera-Montavez, Aleksandar, Krstic, David, Matallanas, Max, Kotlyar, Igor, Jurisica, Jasna, Curak, Victoria, Wong, Igor, Stagljar, Thierry, LeBihan, Lisa, Imrie, Priyanka, Pillai, Miriam A, Lynn, Erik, Fasterius, Cristina, Al-Khalili Szigyarto, James, Breen, Christina, Kiel, Luis, Serrano, Nora, Rauch, Oleksii, Rukhlenko, Boris N, Kholodenko, Luis F, Iglesias-Martinez, Colm J, Ryan, Ruth, Pilkington, Patrizia, Cammareri, Owen, Sansom, Steven, Shave, Manfred, Auer, Nicola, Horn, Franziska, Klose, Marius, Ueffing, Karsten, Boldt, David J, Lynn, Walter, Kolch
Publikováno v:
Nature Communications
Protein-protein-interaction networks (PPINs) organize fundamental biological processes, but how oncogenic mutations impact these interactions and their functions at a network-level scale is poorly understood. Here, we analyze how a common oncogenic K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f4c4c124719b557c7e00a1b876ae91ba
https://pubmed.ncbi.nlm.nih.gov/31980649
https://pubmed.ncbi.nlm.nih.gov/31980649
Autor:
Juan Antonio Vizcaíno, Andrew F. Jarnuczak, Henning Hermjakob, Manuel Bernal-Llinares, Eric W. Deutsch, Robert L. Moritz, Attila Csordas, David S. Campbell, Yasset Perez-Riverol, Mingxun Wang, Tobias Ternent, Shujiro Okuda, Zhi Sun, Nuno Bandeira, Yasushi Ishihama, Jeremy Carver, Shin Kawano
Publikováno v:
Nucleic Acids Research
The ProteomeXchange (PX) Consortium of proteomics resources (http://www.proteomexchange.org) was formally started in 2011 to standardize data submission and dissemination of mass spectrometry proteomics data worldwide. We give an overview of the curr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7bb1f7b0559485269ad05339e4ba1c3e
https://doi.org/10.1093/nar/gkw936
https://doi.org/10.1093/nar/gkw936
Autor:
Heather L. Wiencko, Ivan H. Goenawan, Tanja Muetze, Manuel Bernal-Llinares, David J. Lynn, Kenneth Bryan
Publikováno v:
F1000Research
Highly connected nodes (hubs) in biological networks are topologically important to the structure of the network and have also been shown to be preferentially associated with a range of phenotypes of interest. The relative importance of a hub node, h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6345249a3ece94760f5968b317ee376
http://europepmc.org/articles/PMC5105880
http://europepmc.org/articles/PMC5105880
Autor:
Mohamed Ali Jarboui, Karsten Boldt, Cinzia Raso, Kenneth Bryan, Manuel Bernal-Llinares, Jens Rauch, David J. Lynn, Brendan McCann
Recent advances in mass-spectrometry-based proteomics are now facilitating ambitious large-scale investigations of the spatial and temporal dynamics of the proteome; however, the increasing size and complexity of these data sets is overwhelming curre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ace527362fd853ecca6fe589b43183d