Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Manuel Bernabé‐García"'
Autor:
Begoña Alburquerque-González, Silvia Montoro-García, Ángel Bernabé-García, Manuel Bernabé-García, Priscila Campioni-Rodrigues, Alejandro Rodríguez-Martínez, Irene Luque, Tuula Salo, Alfonso Pérez-Garrido, Horacio Pérez-Sánchez, María Luisa Cayuela, Ginés Luengo-Gil, Enrico Luchinat, Fatima Postigo-Corrales, Tommaso Staderini, Francisco José Nicolás, Pablo Conesa-Zamora
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 179, Iss , Pp 117411- (2024)
Externí odkaz:
https://doaj.org/article/2012b987a1934b849214c3d3ea5cdcaf
Autor:
Begoña Alburquerque-González, Silvia Montoro-García, Ángel Bernabé-García, Manuel Bernabé-García, Priscila Campioni-Rodrigues, Alejandro Rodríguez-Martínez, Irene Luque, Tuula Salo, Alfonso Pérez-Garrido, Horacio Pérez-Sánchez, María Luisa Cayuela, Ginés Luengo-Gil, Enrico Luchinat, Fatima Postigo-Corrales, Tommaso Staderini, Francisco José Nicolás, Pablo Conesa-Zamora
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 175, Iss , Pp 116785- (2024)
Rearrangement of the actin cytoskeleton is a prerequisite for carcinoma cells to develop cellular protrusions, which are required for migration, invasion, and metastasis. Fascin is a key protein involved in actin bundling and is expressed in aggressi
Externí odkaz:
https://doaj.org/article/d5c1f0177bc1443697dce8edda81a4fc
Autor:
Manuel Bernabé‐García, Elena Martínez‐Balsalobre, Diana García‐Moreno, Jesús García‐Castillo, Beatriz Revilla‐Nuin, Elena Blanco‐Alcaina, Victoriano Mulero, Francisca Alcaraz‐Pérez, María L. Cayuela
Publikováno v:
Molecular Oncology, Vol 15, Iss 7, Pp 1818-1834 (2021)
Telomerase reverse transcriptase (TERT) maintains telomere homeostasis, thus ensuring chromosome stability and cell proliferation. In addition, several telomere‐independent functions of human TERT have been described. In this study, we report that
Externí odkaz:
https://doaj.org/article/310687909ba642c2bc2405940c482ed2
Autor:
Begoña Alburquerque-González, Manuel Bernabé-García, Silvia Montoro-García, Ángel Bernabé-García, Priscila Campioni Rodrigues, Javier Ruiz Sanz, Fernando F. López-Calderón, Irene Luque, Francisco José Nicolas, María Luisa Cayuela, Tuula Salo, Horacio Pérez-Sánchez, Pablo Conesa-Zamora
Publikováno v:
Experimental and Molecular Medicine, Vol 52, Iss 2, Pp 281-292 (2020)
Colorectal cancer: Antitumor antidepressant The antidepressant drug imipramine can block the activity of a protein that contributes to the progression of certain aggressive tumors. Serrated adenocarcinoma (SAC) is a form of colorectal cancer with a p
Externí odkaz:
https://doaj.org/article/a4c0dcae753643f4b932658c0f7d73c0
Autor:
Monique Anchelin, Francisca Alcaraz-Pérez, Carlos M. Martínez, Manuel Bernabé-García, Victoriano Mulero, María L. Cayuela
Publikováno v:
Disease Models & Mechanisms, Vol 6, Iss 5, Pp 1101-1112 (2013)
SUMMARY The study of telomere biology is crucial to the understanding of aging and cancer. In the pursuit of greater knowledge in the field of human telomere biology, the mouse has been used extensively as a model. However, there are fundamental diff
Externí odkaz:
https://doaj.org/article/04c0a9ffe16e423785215282aa03fbe4
Autor:
Virginia C Rodriguez-Cortez, Francisca Alcaraz-Pérez, Leonard I. Zon, Isaac Adatto, Miriam Fernandez-Lajarín, Diana García-Moreno, Victoriano Mulero, María L. Cayuela, Suneet Agarwal, Clara Bueno, Manuel Bernabé-García, Elena Martínez-Balsalobre, Marlies P. Rossmann, Ana B. Pérez-Oliva, Pablo Menendez, Jesús García-Castillo
Publikováno v:
Proc Natl Acad Sci U S A
Dyskeratosis congenita (DC) is a rare inherited bone marrow failure and cancer predisposition syndrome caused by mutations in telomerase or telomeric proteins. Here, we report that zebrafish telomerase RNA (terc) binds to specific DNA sequences of ma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05a1cfeed783a66cdec2bd5950a55f25
https://doi.org/10.1073/pnas.2015528118
https://doi.org/10.1073/pnas.2015528118
Autor:
Francisca Alcaraz-Pérez, Victoriano Mulero, Elena Blanco-Alcaina, Jesús García-Castillo, Manuel Bernabé-García, Elena Martínez-Balsalobre, Beatriz Revilla-Nuin, Diana García-Moreno, María L. Cayuela
Publikováno v:
Molecular Oncology
Molecular Oncology, Vol 15, Iss 7, Pp 1818-1834 (2021)
Molecular Oncology, Vol 15, Iss 7, Pp 1818-1834 (2021)
Telomerase reverse transcriptase (TERT) maintains telomere homeostasis, thus ensuring chromosome stability and cell proliferation. In addition, several telomere‐independent functions of human TERT have been described. In this study, we report that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bcb69f40644c2c6c170f6fd286a61eb1
https://doi.org/10.1002/1878-0261.12943
https://doi.org/10.1002/1878-0261.12943
Autor:
Ángel Bernabé-García, María Luisa Cayuela-Fuentes, Manuel Bernabé-García, Pablo Conesa-Zamora, Irene Luque, Horacio Pérez-Sánchez, Begoña Alburquerque-González, Francisco J. Nicolás, Javier Ruiz-Sanz, Silvia Montoro-García, Leonardo Gonnelli, Enrico Luchinat, Lucia Banci, Jorge Peña-García, Fernando F López-Calderón
Publikováno v:
Digibug: Repositorio Institucional de la Universidad de Granada
Universidad de Granada (UGR)
Digibug. Repositorio Institucional de la Universidad de Granada
instname
Cancers, Vol 13, Iss 861, p 861 (2021)
Cancers
Volume 13
Issue 4
Universidad de Granada (UGR)
Digibug. Repositorio Institucional de la Universidad de Granada
instname
Cancers, Vol 13, Iss 861, p 861 (2021)
Cancers
Volume 13
Issue 4
Simple Summary: Colorectal cancer (CRC) is the third leading cause of cancer-related deaths worldwide. Serrated adenocarcinoma (SAC) has been recently recognized by the WHO as a histological CRC with bad prognosis. Consistent with previous evidence,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e89816bc00310824e9253ea01139a7d
https://pubmed.ncbi.nlm.nih.gov/33670655
https://pubmed.ncbi.nlm.nih.gov/33670655
Autor:
Francisco J. Nicolás, Horacio Pérez-Sánchez, María L. Cayuela, Priscila Campioni Rodrigues, Irene Luque, Helena den-Haan, Tuula Salo, Begoña Alburquerque-González, Silvia Montoro-García, Ángel Bernabé-García, Pablo Conesa-Zamora, Manuel Bernabé-García
Tumor invasion and metastasis involve processes in which actin cytoskeleton rearrangement induced by Fascin1 plays a crucial role. Indeed, Fascin1 has been found overexpressed in tumors with worse prognosis. Migrastatin and its analogues target Fasci
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07761ad32d917d5e155c875dc8d2e9ec
http://hdl.handle.net/10138/325423
http://hdl.handle.net/10138/325423
Autor:
Manuel Bernabé-García, Elena Martínez-Balsalobre, Beatriz Revilla-Nuin, Victoriano Mulero, Francisca Alcaraz-Pérez, Elena Blanco-Alcaina, María L. Cayuela, Diana García-Moreno, Jesús García-Castillo
The classical activity of telomerase (TERT) is to maintain telomere homeostasis, ensuring chromosome stability and cellular proliferation. However, increasing evidences of telomere-independent human TERT functions have been lastly obtained. We report
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28787b3b458f314e7c5771a81254df37