Zobrazeno 1 - 10
of 83
pro vyhledávání: '"Manuel B. Aguilar"'
Autor:
Luis Fernando Díaz-Peña, Torres-Ortiz Daniela, Manuel B. Aguilar, Enoch Luis, Fernando Lazcano-Pérez, Roberto Arreguín-Espinosa, Arturo Hernandez-Cruz, César Ibarra-Alvarado, Alejandro García-Arredondo
Publikováno v:
Toxicon: X, Vol 18, Iss , Pp 100151- (2023)
Venoms from tarantulas contain low molecular weight vasodilatory compounds whose biological action is conceived as part of the envenomation strategy due to its propagative effects. However, some properties of venom-induced vasodilation do not match t
Externí odkaz:
https://doaj.org/article/9d6f18d734924adb8675b7c7a15089da
Autor:
Antònia Colom-Casasnovas, Edith Garay, Abraham Cisneros-Mejorado, Manuel B. Aguilar, Fernando Lazcano-Pérez, Rogelio O. Arellano, Judith Sánchez-Rodríguez
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-15 (2022)
Abstract Toxin production in nematocysts by Cnidaria phylum represents an important source of bioactive compounds. Using electrophysiology and, heterologous expression of mammalian ion channels in the Xenopus oocyte membrane, we identified two main e
Externí odkaz:
https://doaj.org/article/f6006a80f1c14ab48d8e96a3de13e0b9
Autor:
Luis Martínez-Hernández, Estuardo López-Vera, Manuel B. Aguilar, Ximena C. Rodriguez-Ruiz, Mónica A. Ortíz-Arellano
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 14, p 11513 (2023)
The first conotoxin affecting the voltage-gated potassium channels of the EAG family was identified and characterized from the venom of the vermivorous species Conus spurius from the Gulf of Mexico. This conopeptide, initially named Cs68 and later de
Externí odkaz:
https://doaj.org/article/fc239c1161db4c80aaea43c96e6b0bb1
Autor:
Ximena C. Rodriguez-Ruiz, Manuel B. Aguilar, Mónica A. Ortíz-Arellano, Helena Safavi-Hemami, Estuardo López-Vera
Publikováno v:
Toxins, Vol 14, Iss 8, p 510 (2022)
We isolated a new dimeric conotoxin with inhibitory activity against neuronal nicotinic acetylcholine receptors. Edman degradation and transcriptomic studies indicate a homodimeric conotoxin composed by two chains of 47 amino acid in length. It has t
Externí odkaz:
https://doaj.org/article/154a7401e5dd46f284553b7718f21357
Autor:
Roberto Zamora-Bustillos, Mario Alberto Martínez-Núñez, Manuel B. Aguilar, Reyna Cristina Collí-Dula, Diego Alfredo Brito-Domínguez
Publikováno v:
Marine Drugs, Vol 19, Iss 10, p 547 (2021)
Marine gastropods of the genus Conus, comprising more than 800 species, have the characteristic of injecting worms and other prey with venom. These conopeptide toxins, highly diverse in structure and action, are highly potent and specific for their m
Externí odkaz:
https://doaj.org/article/c149dca72bfc4774b85d1784874a3c19
Autor:
Estuardo López-Vera, Luis Martínez-Hernández, Manuel B. Aguilar, Elisa Carrillo, Joanna Gajewiak
Publikováno v:
Marine Drugs, Vol 18, Iss 8, p 425 (2020)
Recently, Conorfamide-Sr3 (CNF-Sr3) was isolated from the venom of Conus spurius and was demonstrated to have an inhibitory concentration-dependent effect on the Shaker K+ channel. The voltage-gated potassium channels play critical functions on cellu
Externí odkaz:
https://doaj.org/article/519db0dd0bf7473cb3755f8b039bfd6b
Autor:
Arisaí C. Hernández-Sámano, Andrés Falcón, Fernando Zamudio, César V.F. Batista, Jesús Emilio Michel-Morfín, Víctor Landa-Jaime, Estuardo López-Vera, Michael C. Jeziorski, Manuel B. Aguilar
Publikováno v:
Toxins, Vol 11, Iss 7, p 405 (2019)
Conus snails produce venoms containing numerous peptides such as the α-conotoxins (α-CTXs), which are well-known nicotinic acetylcholine receptor (nAChR) antagonists. Thirty-eight chromatographic fractions from Conus princeps venom extract were iso
Externí odkaz:
https://doaj.org/article/de58c346d6d145f0a3bf1356fe578d68
Publikováno v:
Toxins, Vol 5, Iss 12, Pp 2420-2433 (2013)
The neurotoxic effects produced by a tentacle venom extract and a fraction were analyzed and correlated by in vivo and in vitro approaches. The tentacle venom extract exhibited a wide range of protein components (from 24 to >225 kDa) and produced tet
Externí odkaz:
https://doaj.org/article/c31d4daaef1b42b7833ca567c7b09399
Autor:
Maura Téllez-Téllez,, Gerardo Diaz-Godinez,, Manuel B. Aguilar,, Carmen Sánchez,, Francisco J. Fernández
Publikováno v:
BioResources, Vol 7, Iss 2, Pp 2038-2050 (2012)
In this work, a gene (lacP83) encoding a Pleurotus ostreatus laccase isoenzyme expressed in submerged fermentation conditions is described. A 2,887 bp sequence was obtained from a genomic library of P. ostreatus by using a PCR inverse strategy. The c
Externí odkaz:
https://doaj.org/article/1827e2554db949b8ab7f2992d577e3bc
Autor:
Johanna Bernáldez, Samanta Jiménez, Luis Javier González, Jesús Noda Ferro, Enrique Soto, Emilio Salceda, Daniela Chávez, Manuel B. Aguilar, Alexei Licea-Navarro
Publikováno v:
Toxins, Vol 8, Iss 2, p 39 (2016)
A novel conotoxin, named as PiVIIA, was isolated from the venom of Conus princeps, a marine predatory cone snail collected in the Pacific Southern Coast of Mexico. Chymotryptic digest of the S-alkylated peptide in combination with liquid chromatograp
Externí odkaz:
https://doaj.org/article/d07aae8992e74f5a92042c0fb639be2f