Zobrazeno 1 - 10
of 52
pro vyhledávání: '"Manuel A. Podestà"'
Autor:
Manuel A. Podestà, Cecilia B. Cavazzoni, Benjamin L. Hanson, Elsa D. Bechu, Garyfallia Ralli, Rachel L. Clement, Hengcheng Zhang, Pragya Chandrakar, Jeong-Mi Lee, Tamara Reyes-Robles, Reza Abdi, Alos Diallo, Debattama R. Sen, Peter T. Sage
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-17 (2023)
Abstract Follicular helper T (Tfh) cells are essential for the formation of high affinity antibodies after vaccination or infection. Although the signals responsible for initiating Tfh differentiation from naïve T cells have been studied, the signal
Externí odkaz:
https://doaj.org/article/a14d22d7bc254dbd9e629c721c510730
Autor:
Hengcheng Zhang, Cecilia B. Cavazzoni, Manuel A. Podestà, Elsa D. Bechu, Garyfallia Ralli, Pragya Chandrakar, Jeong-Mi Lee, Ismail Sayin, Stefan G. Tullius, Reza Abdi, Anita S. Chong, Bruce R. Blazar, Peter T. Sage
Publikováno v:
JCI Insight, Vol 8, Iss 20 (2023)
Follicular helper T (Tfh) cells have been implicated in controlling rejection after allogeneic kidney transplantation, but the precise subsets, origins, and functions of Tfh cells in this process have not been fully characterized. Here we show that a
Externí odkaz:
https://doaj.org/article/5122775d69f9498d8cea514882fb5871
Autor:
Annalisa Perna, Barbara Ruggiero, Manuel Alfredo Podestà, Luca Perico, Silvia Orisio, Hanna Debiec, Giuseppe Remuzzi, Piero Ruggenenti
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Rituximab is one of the first-line therapies for patients with membranous nephropathy (MN) at high risk of progression towards kidney failure. We investigated whether the response to Rituximab was affected by sex and anti-PLA2R antibody levels in 204
Externí odkaz:
https://doaj.org/article/525496c3e11d4e5a8c05e90040ea964b
Autor:
Manuel Alfredo Podestà, Megan Sykes
Publikováno v:
Frontiers in Immunology, Vol 12 (2022)
Chronic rejection and immunosuppression-related toxicity severely affect long-term outcomes of kidney transplantation. The induction of transplantation tolerance – the lack of destructive immune responses to a transplanted organ in the absence of i
Externí odkaz:
https://doaj.org/article/68fef84bbfac4745b790751954545823
Autor:
Delia Gagliardi, Irene Faravelli, Manuel Alfredo Podestà, Roberta Brusa, Eleonora Mauri, Domenica Saccomanno, Alessio Di Fonzo, Sara Bonato, Elio Scarpini, Nereo Bresolin, Giacomo Pietro Comi, Stefania Corti
Publikováno v:
Frontiers in Neurology, Vol 12 (2021)
Guillain-Barré syndrome (GBS) is an inflammatory polyradiculopathy with potentially severe complications. Clinical tools for risk stratification have been developed, but no definitive prognostic biomarker has been reported. Hyponatremia is frequent
Externí odkaz:
https://doaj.org/article/d70ecafd3323443a8f750ab4aa16fd13
Autor:
Sofia Bin, Kelly Budge, Micaela Gentile, Manuel Alfredo Podestà, Yaseen Khan, Jamil R. Azzi, Luis Sanchez Russo, Gaetano La Manna, Paolo Cravedi
Publikováno v:
Kidney360. 4:381-386
Publikováno v:
Frontiers in Immunology, Vol 11 (2021)
Transplantation is the gold-standard treatment for the failure of several solid organs, including the kidneys, liver, heart, lung and small bowel. The use of tailored immunosuppressive agents has improved graft and patient survival remarkably in earl
Externí odkaz:
https://doaj.org/article/7d75b72dcf4d41febe68013fb782358f
Publikováno v:
Frontiers in Medicine, Vol 7 (2020)
Focal segmental glomerulosclerosis (FSGS) is a histological term that describes a pathologic renal entity affecting both adults and children, with a wide array of possible underlying etiologies. Podocyte damage with scarring, the hallmark of this con
Externí odkaz:
https://doaj.org/article/a938be4cc9bd415189ca82c0efa9b49f
Autor:
Hengcheng, Zhang, Cecilia B, Cavazzoni, Benjamin L, Hanson, Elsa D, Bechu, Manuel A, Podestà, Jamil, Azzi, Bruce R, Blazar, Anita S, Chong, Daniel, Kreisel, Alessandro, Alessandrini, Peter T, Sage
Publikováno v:
Transplantation. 107:e47-e57
Following allogeneic kidney transplantation, a substantial proportion of graft loss is attributed to the formation of donor-specific antibodies and antibody-mediated rejection. B cells infiltrate kidney grafts during antibody-mediated rejection; howe
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
In solid organ transplantation lifelong immunosuppression exposes transplant recipients to life-threatening complications, such as infections and malignancies, and to severe side effects. Cellular therapy with mesenchymal stromal cells (MSC) has rece
Externí odkaz:
https://doaj.org/article/31b33dc94b3d445b95daf7a0662b2a68