Výsledky vyhledávání - "Manuel A. Baarslag"

How often do we perform painful and stressful procedures in the paediatric intensive care unit? A prospective observational study

Autor: Sharan Jhingoer, Manuel A. Baarslag, Dick Tibboel, Erwin Ista, Karel Allegaert, Monique van Dijk

Publikováno v: Australian Critical Care, 32(1), 4-10. Elsevier Ireland Ltd

BACKGROUND: Adequate analgesia and sedation is crucial in critical care. There is little knowledge on the extent of painful and stressful procedures on children admitted to a paediatric intensive care unit (PICU) and its analgesic and/or sedative man

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d47283a10ed8d174bdb9aff21a51d66
https://pure.eur.nl/en/publications/c2ae7a21-f3e5-4420-ba4f-9416156f4b9a

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Pharmacological sedation management in the paediatric intensive care unit

Autor: Monique van Dijk, Karel Allegaert, Dick Tibboel, Catherijne A. J. Knibbe, Manuel A. Baarslag

Publikováno v: Journal of Pharmacy and Pharmacology, 69(5), 498-513. Wiley-Blackwell

Objective This review addresses sedation management on paediatric intensive care units and possible gaps in the knowledge of optimal sedation strategies. We present an overview of the commonly used sedatives and their pharmacokinetic and pharmacodyna

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57b3a8b8a22b51856e0b3d419e20ecdd
https://pure.eur.nl/en/publications/e240ce22-b9bb-4f7c-9d0e-5b099d9fe1c6

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Paracetamol and morphine for infant and neonatal pain; still a long way to go?

Autor: Karel Allegaert, Catherijne A. J. Knibbe, Dick Tibboel, Manuel A. Baarslag, Sinno H.P. Simons, John N. van den Anker, Monique van Dijk

Publikováno v: Expert Review of Clinical Pharmacology, 10(1), 111-126. Taylor & Francis Ltd

Introduction Pharmacologic pain management in newborns and infants is often based on limited scientific data. To close the knowledge gap, drug-related research in this population is increasingly supported by the authorities, but remains very challeng

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9ff3e716cf3a03c4d90249d59e9b373
https://doi.org/10.1080/17512433.2017.1254040

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Quality and clinical supply considerations of Paediatric Investigation Plans for IV preparations-A case study with the FP7 CloSed project

Autor: Catherine Tuleu, Antje Neubert, Jackie Winslade, Mine Orlu Gul, Sara M. Hanning, Manuel A. Baarslag

Publikováno v: International Journal of Pharmaceutics, 511(2), 1158-1162. Elsevier

A Paediatric Investigation Plan (PIP) is a development plan that aims to ensure that sufficient data are obtained through studies in paediatrics to support the generation of marketing authorisation of medicines for children. This paper highlights som

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2153a31c99cfe40984e3ce07e1961e1
https://doi.org/10.1016/j.ijpharm.2016.04.051

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Clinically effective implementation of intravenous paracetamol as primary analgesia after major surgery in neonates and young infants

Autor: Joost van Rosmalen, Erwin Ista, Dick Tibboel, Saskia N. de Wildt, Monique van Dijk, Tom G. de Leeuw, Manuel A. Baarslag

Publikováno v: Archives of Disease in Childhood, 103, 12, pp. 1168-1169
Archives of Disease in Childhood, 103(12), 1168-1169. BMJ Publishing Group
Archives of Disease in Childhood, 103, 1168-1169

We previously showed that intravenous paracetamol as primary analgesic after major non-cardiac (laparotomy or thoracotomy) surgery in infants

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a458824bd349008ff574a2a0f1137005
https://pubmed.ncbi.nlm.nih.gov/29991471

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The CLOSED trial; CLOnidine compared with midazolam for SEDation of paediatric patients in the intensive care unit: Study protocol for a multicentre randomised controlled trial

Autor: Antje Neubert, Dick Tibboel, Sara M. Hanning, Pavla Pokorná, Jackie Winslade, Alessandra Simonetti, Deborah Roberts, Joost van Rosmalen, Joseph F. Standing, Tuuli Metsvaht, Yucheng Sheng, Wolfgang Rascher, Manuel A. Baarslag, Louise Rawcliffe, Peter Larsson, Monique van Dijk, Viviana Giannuzzi

Publikováno v: BMJ Open, 7(6):e016031. BMJ Publishing Group
BMJ Open

Introduction Sedation is an essential part of paediatric critical care. Midazolam, often in combination with opioids, is the current gold standard drug. However, as it is a far-from-ideal agent, clonidine is increasingly being used in children. This

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2450cb2bd48914705e21730a53b0dde
https://pure.eur.nl/en/publications/c2810e5b-f9b4-4e92-a2e6-4024da03fded

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Delirium in Critically Ill Children: An International Point Prevalence Study

Publikováno v: Critical Care Medicine, 45(4), 584-590. Lippincott Williams & Wilkins

Objectives: To determine prevalence of delirium in critically ill children and explore associated risk factors. Design: Multi-institutional point prevalence study. Setting: Twenty-five pediatric critical care units in the United States, the Netherlan

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b18f8bbdb6687112c5abeae501d64c4d
https://pubmed.ncbi.nlm.nih.gov/28291099

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Cardiovascular risk assessment in haemophilia patients

Autor: Marjolein Peters, S. Biere-Rafi, Roderik A. Kraaijenhagen, Harry R. Büller, Marieke J. H. A. Kruip, Pieter Willem Kamphuisen, Martin den Heijer, Manuel A. Baarslag

Publikováno v: Thrombosis and Haemostasis, 105, 2, pp. 274-8
Thrombosis and Haemostasis, 105(2), 274-278. GEORG THIEME VERLAG KG
Thrombosis and Haemostasis, 105, 274-8
Thrombosis and haemostasis, 105(2), 274-278. Schattauer GmbH
Thrombosis and Haemostasis, 105(2), 274-278. Georg Thieme Verlag

SummaryHaemophilia patients have a reduced cardiovascular mortality, which may be the result of a lifelong deficiency of factor VIII or IX. On the other hand, the prevalence of risk factors may differ in these chronically ill patients compared to the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f2945cbbf57c97dbe0798167226514f9
https://hdl.handle.net/2066/95703

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