Zobrazeno 1 - 10
of 63
pro vyhledávání: '"Manuel A Podestà"'
Autor:
Manuel A. Podestà, Cecilia B. Cavazzoni, Benjamin L. Hanson, Elsa D. Bechu, Garyfallia Ralli, Rachel L. Clement, Hengcheng Zhang, Pragya Chandrakar, Jeong-Mi Lee, Tamara Reyes-Robles, Reza Abdi, Alos Diallo, Debattama R. Sen, Peter T. Sage
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-17 (2023)
Abstract Follicular helper T (Tfh) cells are essential for the formation of high affinity antibodies after vaccination or infection. Although the signals responsible for initiating Tfh differentiation from naïve T cells have been studied, the signal
Externí odkaz:
https://doaj.org/article/a14d22d7bc254dbd9e629c721c510730
Autor:
Hengcheng Zhang, Cecilia B. Cavazzoni, Manuel A. Podestà, Elsa D. Bechu, Garyfallia Ralli, Pragya Chandrakar, Jeong-Mi Lee, Ismail Sayin, Stefan G. Tullius, Reza Abdi, Anita S. Chong, Bruce R. Blazar, Peter T. Sage
Publikováno v:
JCI Insight, Vol 8, Iss 20 (2023)
Follicular helper T (Tfh) cells have been implicated in controlling rejection after allogeneic kidney transplantation, but the precise subsets, origins, and functions of Tfh cells in this process have not been fully characterized. Here we show that a
Externí odkaz:
https://doaj.org/article/5122775d69f9498d8cea514882fb5871
Autor:
Sofia Bin, Chiara Cantarelli, Julian K. Horwitz, Micaela Gentile, Manuel Alfredo Podestà, Gaetano La Manna, Peter S. Heeger, Paolo Cravedi
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
BackgroundAdministration of recombinant erythropoietin (EPO), a kidney-produced hormone with erythropoietic functions, has been shown to have multiple immunoregulatory effects in mice and humans, but whether physiological levels of EPO regulate immun
Externí odkaz:
https://doaj.org/article/c8f23f4f142d45d783bbc302d4349977
Autor:
Annalisa Perna, Barbara Ruggiero, Manuel Alfredo Podestà, Luca Perico, Silvia Orisio, Hanna Debiec, Giuseppe Remuzzi, Piero Ruggenenti
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Rituximab is one of the first-line therapies for patients with membranous nephropathy (MN) at high risk of progression towards kidney failure. We investigated whether the response to Rituximab was affected by sex and anti-PLA2R antibody levels in 204
Externí odkaz:
https://doaj.org/article/525496c3e11d4e5a8c05e90040ea964b
Autor:
Federica Casiraghi, Marta Todeschini, Manuel Alfredo Podestà, Marilena Mister, Barbara Ruggiero, Matias Trillini, Camillo Carrara, Olimpia Diadei, Alessandro Villa, Ariela Benigni, Giuseppe Remuzzi
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 9, p 7687 (2023)
Immune dysregulation plays a key role in the pathogenesis of steroid-dependent/frequently relapsing nephrotic syndrome (SDNS/FRNS). However, in contrast with evidence from the pediatric series, no major B- or T-cell alterations have been described fo
Externí odkaz:
https://doaj.org/article/e3f9ba8523e449bcabe5290bf8ae2bc2
Publikováno v:
Biomedicines, Vol 11, Iss 2, p 279 (2023)
Results from recent randomized controlled trials on inhibitors of the sodium-glucose cotransporter 2 (SGLT2) have determined a paradigm shift in the treatment of patients with type 2 diabetes mellitus. These agents have been shown not only to amelior
Externí odkaz:
https://doaj.org/article/2f737967b1294700b067a3751b995ddc
Autor:
Manuel Alfredo Podestà, Megan Sykes
Publikováno v:
Frontiers in Immunology, Vol 12 (2022)
Chronic rejection and immunosuppression-related toxicity severely affect long-term outcomes of kidney transplantation. The induction of transplantation tolerance – the lack of destructive immune responses to a transplanted organ in the absence of i
Externí odkaz:
https://doaj.org/article/68fef84bbfac4745b790751954545823
Autor:
Delia Gagliardi, Irene Faravelli, Manuel Alfredo Podestà, Roberta Brusa, Eleonora Mauri, Domenica Saccomanno, Alessio Di Fonzo, Sara Bonato, Elio Scarpini, Nereo Bresolin, Giacomo Pietro Comi, Stefania Corti
Publikováno v:
Frontiers in Neurology, Vol 12 (2021)
Guillain-Barré syndrome (GBS) is an inflammatory polyradiculopathy with potentially severe complications. Clinical tools for risk stratification have been developed, but no definitive prognostic biomarker has been reported. Hyponatremia is frequent
Externí odkaz:
https://doaj.org/article/d70ecafd3323443a8f750ab4aa16fd13
Autor:
Manuel Alfredo Podestà, Paolo Cravedi
Publikováno v:
Current opinion in organ transplantation. 27(5)
Autor:
Sofia Bin, Kelly Budge, Micaela Gentile, Manuel Alfredo Podestà, Yaseen Khan, Jamil R. Azzi, Luis Sanchez Russo, Gaetano La Manna, Paolo Cravedi
Publikováno v:
Kidney360. 4:381-386