Zobrazeno 1 - 10
of 92
pro vyhledávání: '"Manuel Sanchez-Alavez"'
Autor:
Manuel Sanchez-Alavez, Nikki Bortell, Liana Basova, Fahumiya Samad, Maria Cecilia Garibaldi Marcondes
Publikováno v:
International Journal of Hyperthermia, Vol 37, Iss 1, Pp 1368-1382 (2020)
Hyperthermia is a potentially lethal side-effect of Methamphetamine (Meth), a stimulant drug. Activation of non-shivering thermogenesis in brown adipose tissue (BAT) is partly responsible for Meth-induced rise in temperature, with contributing sympat
Externí odkaz:
https://doaj.org/article/a74782fc95aa4250a61ead48ec046106
Autor:
Erin L. Brown, Bethany C. Hazen, Elodie Eury, Jean-Sébastien Wattez, Marin L. Gantner, Verena Albert, Sarah Chau, Manuel Sanchez-Alavez, Bruno Conti, Anastasia Kralli
Publikováno v:
iScience, Vol 2, Iss , Pp 221-237 (2018)
Summary: Adrenergic stimulation of brown adipose tissue (BAT) induces acute and long-term responses. The acute adrenergic response activates thermogenesis by uncoupling oxidative phosphorylation and enabling increased substrate oxidation. Long-term,
Externí odkaz:
https://doaj.org/article/24d87279e8a148f7a6c2a7388b0e7c79
Autor:
Simone Mori, Shuei Sugama, William Nguyen, Tatiana Michel, M. Germana Sanna, Manuel Sanchez-Alavez, Rigo Cintron-Colon, Gianluca Moroncini, Yoshihiko Kakinuma, Pamela Maher, Bruno Conti
Publikováno v:
Journal of Neuroinflammation, Vol 14, Iss 1, Pp 1-10 (2017)
Abstract Background The majority of Parkinson’s disease (PD) cases are sporadic and idiopathic suggesting that this neurodegenerative disorder is the result of both environmental and genetic factors. Stress and neuroinflammation are among the facto
Externí odkaz:
https://doaj.org/article/5950a5a111e644f3b24f9e96bcbaf71f
Autor:
Nathaniel L. Matteson, Gabriel W. Hassler, Ezra Kurzban, Madison A. Schwab, Sarah A. Perkins, Karthik Gangavarapu, Joshua I. Levy, Edyth Parker, David Pride, Abbas Hakim, Peter De Hoff, Willi Cheung, Anelizze Castro-Martinez, Andrea Rivera, Anthony Veder, Ariana Rivera, Cassandra Wauer, Jacqueline Holmes, Jedediah Wilson, Shayla N. Ngo, Ashley Plascencia, Elijah S. Lawrence, Elizabeth W. Smoot, Emily R. Eisner, Rebecca Tsai, Marisol Chacón, Nathan A. Baer, Phoebe Seaver, Rodolfo A. Salido, Stefan Aigner, Toan T. Ngo, Tom Barber, Tyler Ostrander, Rebecca Fielding-Miller, Elizabeth H. Simmons, Oscar E. Zazueta, Idanya Serafin-Higuera, Manuel Sanchez-Alavez, Jose L. Moreno-Camacho, Abraham García-Gil, Ashleigh R. Murphy Schafer, Eric McDonald, Jeremy Corrigan, John D. Malone, Sarah Stous, Seema Shah, Niema Moshiri, Alana Weiss, Catelyn Anderson, Christine M. Aceves, Emily G. Spencer, Emory C. Hufbauer, Justin J. Lee, Karthik S. Ramesh, Kelly N. Nguyen, Kieran Saucedo, Refugio Robles-Sikisaka, Kathleen M. Fisch, Steven L. Gonias, Amanda Birmingham, Daniel McDonald, Smruthi Karthikeyan, Natasha K. Martin, Robert T. Schooley, Agustin J. Negrete, Horacio J. Reyna, Jose R. Chavez, Maria L. Garcia, Jose M. Cornejo-Bravo, David Becker, Magnus Isaksson, Nicole L. Washington, William Lee, Richard S. Garfein, Marco A. Luna-Ruiz Esparza, Jonathan Alcántar-Fernández, Benjamin Henson, Kristen Jepsen, Beatriz Olivares-Flores, Gisela Barrera-Badillo, Irma Lopez-Martínez, José E. Ramírez-González, Rita Flores-León, Stephen F. Kingsmore, Alison Sanders, Allorah Pradenas, Benjamin White, Gary Matthews, Matt Hale, Ronald W. McLawhon, Sharon L. Reed, Terri Winbush, Ian H. McHardy, Russel A. Fielding, Laura Nicholson, Michael M. Quigley, Aaron Harding, Art Mendoza, Omid Bakhtar, Sara H. Browne, Jocelyn Olivas Flores, Diana G. Rincon Rodríguez, Martin Gonzalez Ibarra, Luis C. Robles Ibarra, Betsy J. Arellano Vera, Jonathan Gonzalez Garcia, Alicia Harvey-Vera, Rob Knight, Louise C. Laurent, Gene W. Yeo, Joel O. Wertheim, Xiang Ji, Michael Worobey, Marc A. Suchard, Kristian G. Andersen, Abraham Campos-Romero, Shirlee Wohl, Mark Zeller
SummaryThe maturation of genomic surveillance in the past decade has enabled tracking of the emergence and spread of epidemics at an unprecedented level. During the COVID-19 pandemic, for example, genomic data revealed that local epidemics varied con
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::56eb36f6e3f6f8a66062020bd8edb574
https://doi.org/10.1101/2023.03.14.23287217
https://doi.org/10.1101/2023.03.14.23287217
Autor:
Andreu Viader, Daisuke Ogasawara, Christopher M Joslyn, Manuel Sanchez-Alavez, Simone Mori, William Nguyen, Bruno Conti, Benjamin F Cravatt
Publikováno v:
eLife, Vol 5 (2016)
Metabolic specialization among major brain cell types is central to nervous system function and determined in large part by the cellular distribution of enzymes. Serine hydrolases are a diverse enzyme class that plays fundamental roles in CNS metabol
Externí odkaz:
https://doaj.org/article/d5e645537bb8498db55da5346fdc087b
Autor:
Nikki Bortell, Maria Cecilia Garibaldi Marcondes, Liana Basova, Fahumiya Samad, Manuel Sanchez-Alavez
Publikováno v:
International Journal of Hyperthermia, Vol 37, Iss 1, Pp 1368-1382 (2020)
Hyperthermia is a potentially lethal side-effect of Methamphetamine (Meth), a stimulant drug. Activation of non-shivering thermogenesis in brown adipose tissue (BAT) is partly responsible for Meth-induced rise in temperature, with contributing sympat
Autor:
Manuel Sanchez-Alavez, William Nguyen, Simone Mori, Gianluca Moroncini, Andreu Viader, Daniel K Nomura, Benjamin F Cravatt, Bruno Conti
Publikováno v:
PLoS ONE, Vol 10, Iss 8, p e0134437 (2015)
Cyclooxygenase inhibitors such as ibuprofen have been used for decades to control fever through reducing the levels of the pyrogenic lipid transmitter prostaglandin E2 (PGE2). Historically, phospholipases have been considered to be the primary genera
Externí odkaz:
https://doaj.org/article/7714e688c11e4794b6fb2eccd4f6981b
Autor:
Simone Mori, Manuel Sanchez-Alavez, Mona Singh, Derek N. Wills, William Nguyen, Bruno Conti, Dennis Otero, Carlos A. Aguirre, Cindy L. Ehlers
Publikováno v:
Alcohol Clin Exp Res
BACKGROUND Adolescence is a critical period for neural development, and alcohol exposure during adolescence can lead to an elevated risk for health consequences as well as alcohol use disorders. Clinical and experimental data suggest that chronic alc
Autor:
Simone Mori, Manuel Sanchez-Alavez, Derek N. Wills, Cindy L. Ehlers, Dennis Otero, William Nguyen, Bruno Conti
Publikováno v:
Alcohol
Alcohol produces complex effects on the immune system. Moderate alcohol use (1–2 drinks per day) has been shown to produce anti-inflammatory responses in human blood monocytes, whereas, the post mortem brains of severe alcoholics show increased imm
Publikováno v:
Temperature. 6:158-168
During calorie restriction (CR), endotherms adjust several physiological processes including the decrease of core body temperature (Tb) and reduction of energy expenditure. We recently found that CR-induced hypothermia is regulated in a sex-dependent