Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Manuel, Sigle"'
Autor:
Andreas Goldschmied, Manuel Sigle, Wenke Faller, Diana Heurich, Meinrad Gawaz, Karin Anne Lydia Müller
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract Preclinical management of patients with acute chest pain and their identification as candidates for urgent coronary revascularization without the use of high sensitivity troponin essays remains a critical challenge in emergency medicine. We
Externí odkaz:
https://doaj.org/article/afa1ac520fae47d18cee2ff5e9d9e63b
Autor:
Manuel Sigle, Anne-Katrin Rohlfing, Martin Kenny, Sophia Scheuermann, Na Sun, Ulla Graeßner, Verena Haug, Jessica Sudmann, Christian M. Seitz, David Heinzmann, Katja Schenke-Layland, Patricia B. Maguire, Axel Walch, Julia Marzi, Meinrad Paul Gawaz
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-16 (2023)
Abstract Spatial transcriptomics of histological sections have revolutionized research in life sciences and enabled unprecedented insights into genetic processes involved in tissue reorganization. However, in contrast to genomic analysis, the actual
Externí odkaz:
https://doaj.org/article/b7ac1719d6d84968857dbc7a99739fe6
Autor:
Manuel Sigle, Leon Berliner, Erich Richter, Mart van Iersel, Eleonora Gorgati, Ives Hubloue, Maximilian Bamberg, Christian Grasshoff, Peter Rosenberger, Robert Wunderlich
Publikováno v:
Journal of Medical Internet Research, Vol 25, p e44042 (2023)
BackgroundIn cases of terrorism, disasters, or mass casualty incidents, far-reaching life-and-death decisions about prioritizing patients are currently made using triage algorithms that focus solely on the patient’s current health status rather tha
Externí odkaz:
https://doaj.org/article/755237cf9f724fa4ace61a9d3e9cebc6
Autor:
Anne-Katrin Rohlfing, Kyra Kolb, Manuel Sigle, Melanie Ziegler, Alexander Bild, Patrick Münzer, Jessica Sudmann, Valerie Dicenta, Tobias Harm, Mailin-Christin Manke, Sascha Geue, Marcel Kremser, Madhumita Chatterjee, Chunguang Liang, Hendrik von Eysmondt, Thomas Dandekar, David Heinzmann, Manina Günter, Saskia von Ungern-Sternberg, Manuela Büttcher, Tatsiana Castor, Stine Mencl, Friederike Langhauser, Katharina Sies, Diyaa Ashour, Mustafa Caglar Beker, Michael Lämmerhofer, Stella E. Autenrieth, Tilman E. Schäffer, Stefan Laufer, Paulina Szklanna, Patricia Maguire, Matthias Heikenwalder, Karin Anne Lydia Müller, Dirk M. Hermann, Ertugrul Kilic, Ralf Stumm, Gustavo Ramos, Christoph Kleinschnitz, Oliver Borst, Harald F. Langer, Dominik Rath, Meinrad Gawaz
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-20 (2022)
ACKR3 is a critical regulator of platelet-mediated thrombosis and organ injury following ischemia/reperfusion. Platelet ACKR3 surface expression is independently associated with all-cause mortality in patients with cardiovascular diseases.
Externí odkaz:
https://doaj.org/article/bff45f142b4844968bc8a69ceae8231a
Autor:
Annalena Fink, Anne-Katrin Rohlfing, Valerie Dicenta, David Schaale, Marcel Kremser, Zoi Laspa, Manuel Sigle, Xiaoqing Fu, Andreas Pelzer, Melina Fischer, Patrick Münzer, Tatsiana Castor, Karin Anne Lydia Müller, Oliver Borst, Michael Lämmerhofer, Meinrad Paul Gawaz
Publikováno v:
Thrombosis and Haemostasis.
Introduction Hemolysis results in release of free hemoglobin and hemin liberation from erythrocytes. Hemin has been described to induce platelet activation and to trigger thrombosis. Methods We evaluated the effect of hemin on platelet function and s
Autor:
Manuel Sigle, Anne-Katrin Rohlfing, Sophia Scheuermann, Na Sun, Ulla Graeßner, Verena Haug, Jessica Sudmann, Christian Seitz, David Heinzmann, Katja Schenke-Layland, Axel Walch, Julia Marzi, Meinrad Paul Gawaz
Raman spectroscopy data from a section of subendocardial fibrosis, which was mainly used to establish the "Spectromics" approach with established bioinformatic tools. Samples: S01 (subpapillary fibrosis): Raman data, Raman Intensity image at 2940cm-1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6323675844b12e964932fbd3fa1f6c38
Autor:
Manuel Sigle, Leon Berliner, Erich Richter, Mart van Iersel, Eleonora Gorgati, Ives Hubloue, Maximilian Bamberg, Christian Grasshoff, Peter Rosenberger, Robert Wunderlich
Publikováno v:
Journal of Medical Internet Research.
Autor:
Manuel Sigle, Leon Berliner, Erich Richter, Mart van Iersel, Eleonora Gorgati, Ives Hubloue, Maximilian Bamberg, Christian Grasshoff, Peter Rosenberger, Robert Wunderlich
BACKGROUND Background: In cases of terrorism, disasters or mass casualty incidents, far-reaching life-and-death decisions about prioritizing patients are currently made using triage algorithms that focus solely on the patient's current health status
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e51e93ae7b53cf0ee1c97e4621d6cfe7
https://doi.org/10.2196/preprints.44042
https://doi.org/10.2196/preprints.44042
Autor:
Manuel Sigle, Leon Berliner, Erich Richter, Mart van Iersel, Eleonora Gorgati, Ives Hubloue, Maximilian Bamberg, Christian Grasshoff, Peter Rosenberger, Robert Wunderlich
Artificial patient database generated for the publication in a semi-supervised manner and used for analysis. 
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99e725883de3dc56605c9f030568ebc8
Autor:
Anne-Katrin, Rohlfing, Kyra, Kolb, Manuel, Sigle, Melanie, Ziegler, Alexander, Bild, Patrick, Münzer, Jessica, Sudmann, Valerie, Dicenta, Tobias, Harm, Mailin-Christin, Manke, Sascha, Geue, Marcel, Kremser, Madhumita, Chatterjee, Chunguang, Liang, Hendrik, von Eysmondt, Thomas, Dandekar, David, Heinzmann, Manina, Günter, Saskia, von Ungern-Sternberg, Manuela, Büttcher, Tatsiana, Castor, Stine, Mencl, Friederike, Langhauser, Katharina, Sies, Diyaa, Ashour, Mustafa Caglar, Beker, Michael, Lämmerhofer, Stella E, Autenrieth, Tilman E, Schäffer, Stefan, Laufer, Paulina, Szklanna, Patricia, Maguire, Matthias, Heikenwalder, Karin Anne Lydia, Müller, Dirk M, Hermann, Ertugrul, Kilic, Ralf, Stumm, Gustavo, Ramos, Christoph, Kleinschnitz, Oliver, Borst, Harald F, Langer, Dominik, Rath, Meinrad, Gawaz
Platelet activation plays a critical role in thrombosis. Inhibition of platelet activation is a cornerstone in treatment of acute organ ischemia. Platelet ACKR3 surface expression is independently associated with all-cause mortality in CAD patients.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::2174660c459076f47139948dc9022213
https://hdl.handle.net/20.500.12511/9351
https://hdl.handle.net/20.500.12511/9351