Zobrazeno 1 - 10
of 102
pro vyhledávání: '"Manuel, Föcker"'
Autor:
Luisa Sophie Rajcsanyi, Yiran Zheng, Beate Herpertz-Dahlmann, Jochen Seitz, Martina de Zwaan, Wolfgang Herzog, Stefan Ehrlich, Stephan Zipfel, Katrin Giel, Karin Egberts, Roland Burghardt, Manuel Föcker, Jochen Antel, Pamela Fischer-Posovszky, Johannes Hebebrand, Anke Hinney
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-10 (2024)
Abstract Mutations leading to a reduced or loss of function in genes of the leptin-melanocortin system confer a risk for monogenic forms of obesity. Yet, gain of function variants in the melanocortin-4-receptor (MC4R) gene predispose to a lower BMI.
Externí odkaz:
https://doaj.org/article/72d9bff16c3a4d4c9ec66cca2742c072
Autor:
Raphael Hirtz, Lars Libuda, Anke Hinney, Manuel Föcker, Judith Bühlmeier, Paul-Martin Holterhus, Alexandra Kulle, Cordula Kiewert, Berthold P. Hauffa, Johannes Hebebrand, Corinna Grasemann
Publikováno v:
Translational Psychiatry, Vol 12, Iss 1, Pp 1-12 (2022)
Abstract There is preliminary evidence that adrenal steroids other than cortisol may be valuable biomarkers for major depressive disorder (MDD). So far, studies have been conducted in adults only, and conclusions are limited, mainly due to small samp
Externí odkaz:
https://doaj.org/article/0d71ada72cf64eccaa657707a0a37a43
Autor:
Yiran Zheng, Luisa Sophie Rajcsanyi, Beate Herpertz-Dahlmann, Jochen Seitz, Martina de Zwaan, Wolfgang Herzog, Stefan Ehrlich, Stephan Zipfel, Katrin Giel, Karin Egberts, Roland Burghardt, Manuel Föcker, Saad Al-Lahham, Triinu Peters, Lars Libuda, Jochen Antel, Johannes Hebebrand, Anke Hinney
Publikováno v:
Translational Psychiatry, Vol 12, Iss 1, Pp 1-9 (2022)
Abstract Genetic factors are relevant for both eating disorders and body weight regulation. A recent genome-wide association study (GWAS) for anorexia nervosa (AN) detected eight genome-wide significant chromosomal loci. One of these loci, rs10747478
Externí odkaz:
https://doaj.org/article/b0fc275d9ce7472994a1c28253750567
Autor:
Luisa S. Rajcsanyi, Anne Hoffmann, Adhideb Ghosh, Birgit Matrisch-Dinkler, Yiran Zheng, Triinu Peters, Wenfei Sun, Hua Dong, Falko Noé, Christian Wolfrum, Beate Herpertz-Dahlmann, Jochen Seitz, Martina de Zwaan, Wolfgang Herzog, Stefan Ehrlich, Stephan Zipfel, Katrin Giel, Karin Egberts, Roland Burghardt, Manuel Föcker, Linus T. Tsai, Timo D. Müller, Matthias Blüher, Johannes Hebebrand, Raphael Hirtz, Anke Hinney
Publikováno v:
Frontiers in Genetics, Vol 14 (2023)
Increased thermogenesis in brown adipose tissue might have an obesity-reducing effect in humans. In transgenic mice, depletion of genes involved in creatine metabolism results in disrupted thermogenic capacity and altered effects of high-fat feeding
Externí odkaz:
https://doaj.org/article/244dccf20d964dffbae9720581371886
Autor:
Yiran Zheng, Luisa Sophie Rajcsanyi, Manuela Kowalczyk, Johanna Giuranna, Beate Herpertz-Dahlmann, Jochen Seitz, Martina de Zwaan, Wolfgang Herzog, Stefan Ehrlich, Stephan Zipfel, Katrin Giel, Karin Egberts, Roland Burghardt, Manuel Föcker, Saad Al-Lahham, Johannes Hebebrand, Dagmar Fuhrer, Susanne Tan, Denise Zwanziger, Triinu Peters, Anke Hinney
Publikováno v:
Frontiers in Endocrinology, Vol 14 (2023)
ContextThe bone-derived adipokine lipocalin-2 is relevant for body weight regulation by stimulating the leptin-melanocortin pathway.ObjectiveWe aimed to (i) detect variants in the lipocalin-2 gene (LCN2) which are relevant for body weight regulation
Externí odkaz:
https://doaj.org/article/855239045e7e40c5b0b7dc6f0a547ba6
Autor:
Triinu Peters, David Kolar, Manuel Föcker, Katharina Bühren, Brigitte Dahmen, Katja Becker, Linda Weber, Christoph U. Correll, Charlotte Jaite, Karin M. Egberts, Marcel Romanos, Stefan Ehrlich, Maria Seidel, Veit Roessner, Christian Fleischhaker, Alexander von Gontard, Freia Hahn, Michael Huss, Michael Kaess, Tanja Legenbauer, Tobias J. Renner, Ulrike M. E. Schulze, Judith Sinzig, Ida Wessing, Gisela Antony, Beate Herpertz-Dahlmann, Gertraud Gradl-Dietsch, Johannes Hebebrand
Publikováno v:
Child and Adolescent Psychiatry and Mental Health, Vol 15, Iss 1, Pp 1-13 (2021)
Abstract Background Body mass index (BMI) at hospital admission in patients with anorexia nervosa (AN) represents a prognostic marker for mortality, chronicity and future body weight. The current study focused on the associations between BMI standard
Externí odkaz:
https://doaj.org/article/e702c1d2ad174743b7dcb318cc1c3d7b
Autor:
Jana Freff, Lisa Bröker, Rafael Leite Dantas, Kathrin Schwarte, Judith Bühlmeier, Isabelle Kraft, Anke Hinney, Ulrike Buhlmann, Volker Arolt, Udo Dannlowski, Georg Romer, Bernhard T. Baune, Johannes Hebebrand, Manuel Föcker, Judith Alferink
Publikováno v:
Frontiers in Psychiatry, Vol 13 (2022)
Anorexia nervosa (AN) is a severe eating disorder characterized by excessive weight loss and lack of recognition of the seriousness of the current low body weight. Individuals with AN frequently exhibit an enhanced inflammatory state and altered bloo
Externí odkaz:
https://doaj.org/article/05ff4e4197cd49989916aa982b7bb3eb
Publikováno v:
Frontiers in Psychiatry, Vol 13 (2022)
BackgroundAnorexia Nervosa (AN) typically begins during early adolescence, an important phase of personality development. A substantial proportion of adolescent AN patients shows impaired personality functioning, which might be a relevant but underst
Externí odkaz:
https://doaj.org/article/b0843644b0e1478885e4366a3d4a4a0c
Autor:
Jana Freff, Kathrin Schwarte, Lisa Bröker, Judith Bühlmeier, Isabelle Kraft, Dana Öztürk, Anke Hinney, Volker Arolt, Udo Dannlowski, Georg Romer, Bernhard T. Baune, Johannes Hebebrand, Manuel Föcker, Judith Alferink
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Abstract Anorexia nervosa (AN) is a severe eating disorder and often associated with altered humoral immune responses. However, distinct B cell maturation stages in peripheral blood in adolescents with AN have not been characterized. Treatment effect
Externí odkaz:
https://doaj.org/article/f3bc205679ba442ea7f572bacbab22c5
Autor:
Raphael Hirtz, Lars Libuda, Anke Hinney, Manuel Föcker, Judith Bühlmeier, Paul-Martin Holterhus, Alexandra Kulle, Cordula Kiewert, Johannes Hebebrand, Corinna Grasemann
Publikováno v:
Frontiers in Psychiatry, Vol 12 (2021)
There is a distinct increase in the prevalence of depression with the onset of puberty. The role of peripubertal testosterone levels in boys in this context is insufficiently understood and may be modulated by a functional polymorphism of the androge
Externí odkaz:
https://doaj.org/article/d4cedb4db6444c35ab23d35e5c2680ab