Zobrazeno 1 - 10
of 380
pro vyhledávání: '"Manuchair Ebadi"'
Autor:
Anthony H.V. Schapira
Publikováno v:
New England Journal of Medicine. 353:1304-1305
Autor:
Manuchair Ebadi, Sushil Sharma
Publikováno v:
Biomarkers and Genomic Medicine. 6(3):89-98
The Charnoly body (CB) is a pleomorphic, electron-dense, multilamellar, preapoptotic, mitochondrial biomarker of cell injury. Nutritional stress and environmental toxins induce CB formation in highly vulnerable developing neurons because of compromis
Publikováno v:
Neurochemical Research. 39:225-232
Several lines of evidence suggest that the mechanism underlying drug-induced neuronal apoptosis is initiated by the increased production of reactive oxygen species (ROS). 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP), a neurotoxin, has been sho
Publikováno v:
Journal of Pineal Research. 49:382-389
Methamphetamine (METH) is a common drug of abuse that induces toxicity in the central nervous system and is connected to neurological disorders such as Parkinson's disease. METH neurotoxicity is induced by reactive oxygen species (ROS) production and
Publikováno v:
Neuroscience Letters. 461:258-261
Secretion of melatonin by the mammalian pineal gland is primarily regulated by the release of norepinephrine (NE) from sympathetic nerve terminals that originate from the superior cervical ganglia. Peptidergic nerves that originate in the perikarya l
Publikováno v:
Neuroscience Letters. 439:125-128
Alpha-synuclein (alpha-syn) is implicated in the pathogenesis of Parkinson's disease (PD). Mutations in alpha-syn gene or alpha-syn locus (SNCA) triplication are associated with mitochondrial abnormalities and early onset of familial PD. The goals of
Publikováno v:
Neuroscience Letters. 419:59-63
Methamphetamine (METH) is a well-known drug of abuse and neurotoxin that may cause temporary or permanent disturbances in the dopaminergic systems of the brain, predisposing individuals to Parkinsonism. Previously, we have shown that METH causes dopa
Publikováno v:
Neurochemical Research. 32:443-450
Salsolinol, an endogenous neurotoxin, is known to be involved in the pathogenesis of Parkinson's disease (PD). In the present study, we have investigated the effects of salsolinol on the activation of two different signaling pathways that involve c-J
Autor:
Manuchair Ebadi, Sushil Sharma
Publikováno v:
Experimental Biology and Medicine. 231:1576-1583
We have examined potent peroxynitrite ion (ONOO-) generator 3-morpholinosydnonimine (SIN-1)–induced neurotoxicity in control wild-type (controlwt) mice, metallothionein double knockout (MTdko) mice, metallothionein-transgenic (MTtrans) mice, and in