Supplementary Figure Legends from Peripheral Blood TCR Repertoire Profiling May Facilitate Patient Stratification for Immunotherapy against Melanoma

Autor: Mitchell P. Levesque, Reinhard Dummer, John B.A.G. Haanen, Nicolas Pasqual, Pia Kvistborg, Marieke I.G. Raaijmakers, Thi Dan Linh Nguyen-Kim, Jean-François Mouret, Nadia Plantier, Solène Perez, Manuarii Manuel, Simone M. Goldinger, Nicoletta F. Jaberg-Bentele, Phil F. Cheng, Anaïs Courtier, Sabrina A. Hogan

Figure Legends for Supplemental Figures 1-4

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25269a334a7acee2caf869b2771c70d3
https://doi.org/10.1158/2326-6066.22536020

Figure S2 from Peripheral Blood TCR Repertoire Profiling May Facilitate Patient Stratification for Immunotherapy against Melanoma

Autor: Mitchell P. Levesque, Reinhard Dummer, John B.A.G. Haanen, Nicolas Pasqual, Pia Kvistborg, Marieke I.G. Raaijmakers, Thi Dan Linh Nguyen-Kim, Jean-François Mouret, Nadia Plantier, Solène Perez, Manuarii Manuel, Simone M. Goldinger, Nicoletta F. Jaberg-Bentele, Phil F. Cheng, Anaïs Courtier, Sabrina A. Hogan

Lymphocyte to leukocyte ratio in high and low ANC/ALC groups for anti-PD1 treated patients at baseline. (Wilcoxon test)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4002c25ca42799ef82fdb010fd1eb11a
https://doi.org/10.1158/2326-6066.22536029

Figure S4 from Peripheral Blood TCR Repertoire Profiling May Facilitate Patient Stratification for Immunotherapy against Melanoma

Autor: Mitchell P. Levesque, Reinhard Dummer, John B.A.G. Haanen, Nicolas Pasqual, Pia Kvistborg, Marieke I.G. Raaijmakers, Thi Dan Linh Nguyen-Kim, Jean-François Mouret, Nadia Plantier, Solène Perez, Manuarii Manuel, Simone M. Goldinger, Nicoletta F. Jaberg-Bentele, Phil F. Cheng, Anaïs Courtier, Sabrina A. Hogan

3D representation of the TCR diversity. Each peak represents a rearrangement between a given V gene family and a J segment. X axis: TRBV, y axis: TRBJ, z axis relative intensity. The table shows the top 10 rearrangements, listed in decreasing order o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03e0620cf964f5a906679db78d30dc17
https://doi.org/10.1158/2326-6066.22536023

T‐cell receptor diversity as a prognostic biomarker in melanoma patients

Autor: Julie Charles, Manuarii Manuel, Nadia Plantier, Stéphane Mouret, Florence de Fraipont, Laurence Chaperot, Solène Perez, Joel Plumas, Marie-Thérèse Leccia, Isabelle Challende, Caroline Aspord

Publikováno v: Pigment Cell & melanoma research
Pigment Cell & melanoma research, Blackwell Munksgaard, 2020, 33 (4), pp.612-624. ⟨10.1111/pcmr.12866⟩

There is increasing evidence that T-cell receptor (TCR) repertoire diversity can be a predictive biomarker of immune responses in cancer patients. However, the characteristics of the T-cell repertoire together with its prognostic significance in mela

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b0281e7a1eadf3ab4daae2f29ede99d5
https://hal.archives-ouvertes.fr/hal-03329074

P4-09-10: Assessment of Circulating Immune Parameters in Patients with Metastatic Breast Cancer Improves Survival Prediction

Autor: Manuarii Manuel, Cathy Biota, Agathe Bajard, C Menetrier-Caux, J.-Y. Blay, Gilles Clapisson, Sylvie Chabaud, Christophe Caux, Thomas Bachelot, Olivier Tredan

Publikováno v: Cancer Research. 71:P4-09

Background Prediction of survival for metastatic breast cancer (MBC) patients (pts) remains a major clinical challenge. Most studies proposed prognostic scores based on clinical criteria that are often subjective. We already demonstrated that low lym

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::4047ba4822085ed56510408e8536a151
https://doi.org/10.1158/0008-5472.sabcs11-p4-09-10