Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Manu Tewari"'
Tension-suppressed degradation of collagen controls tissue stiffness scaling with fibrillar collagen
Autor:
Karanvir Saini, Sangkyun Cho, Manu Tewari, Abdelaziz Jalil, Mai Wang, Manasvita Vashisth, Alex Kasznel, Kazuhiro Yamamoto, David M. Chenoweth, Dennis E. Discher
Publikováno v:
Biophysical Journal. 122:87a
Autor:
Karanvir Saini, Manu Tewari, Sangkyun Cho, Manasvita Vashisth, Abdelaziz Jalil, Jason C. Andrechak, Alex Kasznel, David Chenoweth, Kazuhiro Yamamoto, Dennis E. Discher
Publikováno v:
Biophysical Journal. 121:492a
Autor:
Dennis E. Discher, Jerome Irianto, Amal Abbas, Irena L. Ivanovska, Sangkyun Cho, Yuntao Xia, Manu Tewari
Publikováno v:
Nucleus
Interphase phosphorylation of lamin-A,C depends dynamically on a cell's microenvironment, including the stiffness of extracellular matrix. However, phosphorylation dynamics is poorly understood for diseased forms such as progerin, a permanently farne
Autor:
Manu Tewari, Jerome Irianto, Cory Alvey, Shane M. Harding, Jiazheng Ji, Andrea J. Liu, Rachel R. Bennett, Yuntao Xia, Roger A. Greenberg, Dennis E. Discher, Avathamsa Athirasala, Charlotte R. Pfeifer
Publikováno v:
Current Biology. 27:210-223
Migration through micron-size constrictions has been seen to rupture the nucleus, release nuclear-localized GFP, and cause localized accumulations of ectopic 53BP1 – a DNA repair protein. Here, constricted migration of two human cancer cell types a
Autor:
Sangkyun Cho, Lawrence J. Dooling, David M. Chenoweth, Manu Tewari, Kazuhiro Yamamoto, Alex Kasznel, Karanvir Saini, Manasvita Vashisth, Charlotte R. Pfeifer, Dennis E. Discher, Jason C. Andrechak, AbdelAziz Jalil, Cory Alvey, Jerome Irianto
Publikováno v:
Biophysical Journal. 118:398a
Autor:
Manu Tewari, Sangkyun Cho, Yuntao Xia, Cory Alvey, Brandon H. Hayes, Kyle R. Spinler, Dennis E. Discher, Lucas R. Smith, Jerome Irianto, Jake Hsu, Charlotte R. Pfeifer, P.C.P. Dave Dingal
Publikováno v:
Current biology : CB, vol 27, iss 14
Marrow-derived macrophages are highly phagocytic, but whether they can also traffic into solid tumors and engulf cancer cells is questionable, given the well-known limitations of tumor-associated macrophages (TAMs). Here, SIRPα on macrophages from m
Autor:
Jerome Irianto, Charlotte R. Pfeifer, Karanvir Saini, Dennis E. Discher, Cory Alvey, Manu Tewari
Publikováno v:
Biophysical Journal. 116:379a
Autor:
Jerome Irianto, Rachel R. Bennett, Shane M. Harding, Andrea J. Liu, Roger A. Greenberg, Dennis E. Discher, Manu Tewari, Charlotte R. Pfeifer, Jiazheng Ji, Irena L. Ivanovska, Yuntao Xia
Cells that migrate through small, rigid pores and that have normal levels of the nuclear structure protein lamin-A exhibit an increase in DNA damage, which is also observed with lamin-A depletion in diseases such as cancer and with many lamin-A mutat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a8ecb822e82a5b26560f95ba69afeab
https://doi.org/10.1101/097162
https://doi.org/10.1101/097162
Autor:
Manu Tewari, Rachel R. Bennett, Jerome Irianto, Yuntao Xia, Roger A. Greenberg, Jiazheng Ji, Avathamsa Athirasala, Cory Alvey, Dennis E. Discher, Charlotte R. Pfeifer, Shane M. Harding, Andrea J. Liu
Publikováno v:
Biophysical Journal. 114:653a
Autor:
Jerome Irianto, Jiazheng Ji, Dennis E. Discher, Avathamsa Athirasala, Cory A. Alvey, Manu Tewari, Rachel R. Bennett, Roger A. Greenberg, Yuntao Xia, Shane M. Harding, Andrea J. Liu, Charlotte R. Pfeifer
Publikováno v:
Biophysical Journal. 112:123a
Normal and diseased cells in vivo sometimes squeeze their nucleus through tissues and basement membrane matrices. Recent studies has shown that constricted migration give rise to an increase in GFP-53BP1 marked DNA damage and to die more frequently,