Zobrazeno 1 - 10
of 4 625
pro vyhledávání: '"Manu M"'
Autor:
Manu M. Savani, Sofia Collignon
Publikováno v:
Political Research Exchange, Vol 6, Iss 1 (2024)
How do voters respond to a co-partisan political candidate after hearing about a serious scandal? We apply qualitative content analysis to open-ended text responses collected from survey respondents, focusing on 159 respondents who remain willing to
Externí odkaz:
https://doaj.org/article/516dcff1a1e1455d93247484425d3ef2
Autor:
Bingnan Li, Patrice Zeis, Yujie Zhang, Alisa Alekseenko, Eliska Fürst, Yerma Pareja Sanchez, Gen Lin, Manu M. Tekkedil, Ilaria Piazza, Lars M. Steinmetz, Vicent Pelechano
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-17 (2023)
Transcriptional memory is key for cellular adaptation. Here the authors show that differences in mRNA stability and mRNA degradation machinery between naïve and primed cells facilitate faster gene expression response to repeated stimuli.
Externí odkaz:
https://doaj.org/article/07c6c17a87b14297806ea44f76865958
Autor:
Jenna I. Wurster, Rachel L. Peterson, Claire E. Brown, Swathi Penumutchu, Douglas V. Guzior, Kerri Neugebauer, William H. Sano, Manu M. Sebastian, Robert A. Quinn, Peter Belenky
Publikováno v:
Cell Reports, Vol 37, Iss 11, Pp 110113- (2021)
Summary: It is well established in the microbiome field that antibiotic (ATB) use and metabolic disease both impact the structure and function of the gut microbiome. But how host and microbial metabolism interacts with ATB susceptibility to affect th
Externí odkaz:
https://doaj.org/article/37f739c394ab406885ecdd963ef285ae
Publikováno v:
Translational Oncology, Vol 14, Iss 2, Pp 101008- (2021)
Externí odkaz:
https://doaj.org/article/12670e3a496747d7ae19c8fff6fdb807
Autor:
Parijat Chakraborty, Ajith V. Pankajam, Gen Lin, Abhishek Dutta, G. Nandanan Krishnaprasad, Manu M. Tekkedil, Akira Shinohara, Lars M. Steinmetz, K. Thazath Nishant
Publikováno v:
G3: Genes, Genomes, Genetics, Vol 7, Iss 5, Pp 1511-1524 (2017)
Meiotic crossover frequencies show wide variation among organisms. But most organisms maintain at least one crossover per homolog pair (obligate crossover). In Saccharomyces cerevisiae, previous studies have shown crossover frequencies are reduced in
Externí odkaz:
https://doaj.org/article/c55bf1940f104ae499997e929d49f645
Autor:
Daniel M Bader, Stefan Wilkening, Gen Lin, Manu M Tekkedil, Kim Dietrich, Lars M Steinmetz, Julien Gagneur
Publikováno v:
Molecular Systems Biology, Vol 11, Iss 1, Pp 1-12 (2015)
Abstract Mechanisms conferring robustness against regulatory variants have been controversial. Previous studies suggested widespread buffering of RNA misexpression on protein levels during translation. We do not find evidence that translational buffe
Externí odkaz:
https://doaj.org/article/4bacfda9e0a84c5281a7082b5dc8c3eb
Autor:
Alphy Rose James, BS Unnikrishnan, R Priya, Manu M Joseph, TK Manojkumar, K Raveendran Pillai, R Shiji, GU Preethi, P Kusumakumary, TT Sreelekha
Publikováno v:
Tumor Biology, Vol 39 (2017)
Imatinib mesylate, a BCR/ABL fusion protein inhibitor, is the first-line treatment against chronic myelogenous leukemia. In spite of its advantageous viewpoints, imatinib still has genuine impediments like undesirable side effects and tumor resistanc
Externí odkaz:
https://doaj.org/article/3c8714b91db54580ace99041f324e889
Publikováno v:
Translational Oncology, Vol 7, Iss 5, Pp 525-536 (2014)
Doxorubicin (Dox) treatment is limited by severe toxicity and frequent episodes of treatment failure. To minimize adverse events and improve drug delivery efficiently and specifically in cancer cells, encapsulation of Dox with naturally obtained gala
Externí odkaz:
https://doaj.org/article/b045fc2e869d4db191d5853f3670e89b
Publikováno v:
Journal of Indian Academy of Oral Medicine and Radiology, Vol 25, Iss 3, Pp 214-217 (2013)
Externí odkaz:
https://doaj.org/article/7d1701616526488eb5a7eb01f024cdcb
Autor:
Julien Gagneur, Oliver Stegle, Chenchen Zhu, Petra Jakob, Manu M Tekkedil, Raeka S Aiyar, Ann-Kathrin Schuon, Dana Pe'er, Lars M Steinmetz
Publikováno v:
PLoS Genetics, Vol 9, Iss 9, p e1003803 (2013)
Unraveling the molecular processes that lead from genotype to phenotype is crucial for the understanding and effective treatment of genetic diseases. Knowledge of the causative genetic defect most often does not enable treatment; therefore, causal in
Externí odkaz:
https://doaj.org/article/b7cad8419f554d248987405983057a0f