Zobrazeno 1 - 8 of 8 pro vyhledávání: '"Manu Kupani"'
1
Akademický článek
Prediction of an immunogenic peptide ensemble and multi-subunit vaccine for Visceral leishmaniasis using bioinformatics approaches
Autor: Manu Kupani, Rajeev Kumar Pandey, Sharad Vashisht, Satyendra Singh, Vijay Kumar Prajapati, Sanjana Mehrotra
Publikováno v: Heliyon, Vol 9, Iss 12, Pp e22121- (2023)
Visceral Leishmaniasis (VL) is a neglected tropical disease of public health importance in the Indian subcontinent. Despite consistent elimination initiatives, the disease has not yet been eliminated and there is an increased risk of resurgence from
Externí odkaz: https://doaj.org/article/95221299ad574340b2d4736128e74bdf
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2
Akademický článek
Genetic association between CDKN2B/CDKN2B-AS1 gene polymorphisms with primary glaucoma in a North Indian cohort: an original study and an updated meta-analysis
Autor: Nanamika Thakur, Manu Kupani, Rashim Mannan, Archna Pruthi, Sanjana Mehrotra
Publikováno v: BMC Medical Genomics, Vol 14, Iss 1, Pp 1-20 (2021)
Abstract Background Variants in CDKN2B/CDKN2B-AS1 have been reported to modulate glaucoma risk in several GWAS across different populations. CDKN2B/CDKN2A encodes tumor suppressor proteins p16INK4A/p15INK4B which influences cell proliferation/senesce
Externí odkaz: https://doaj.org/article/fc46ed43422e4ddbb00bc7363624dd43
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3
Akademický článek
IL-10 and TGF-β Induced Arginase Expression Contributes to Deficient Nitric Oxide Response in Human Visceral Leishmaniasis
Autor: Manu Kupani, Smriti Sharma, Rajeev Kumar Pandey, Rajiv Kumar, Shyam Sundar, Sanjana Mehrotra
Publikováno v: Frontiers in Cellular and Infection Microbiology, Vol 10 (2021)
Nitric oxide (NO) is an anti-microbial effector of the innate immune system which plays major role in non-specific killing of various pathogens including protozoan parasites. However, due to subversion of the host’s immune processes by pathogens, s
Externí odkaz: https://doaj.org/article/bce32e4ccf6b42afbe5fd3f9d318f1fb
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4
Akademický článek
Genetic association of -1562C>T polymorphism in the MMP9 gene with primary glaucoma in a north Indian population.
Autor: Nanamika Thakur, Manu Kupani, Rajeev Kumar Pandey, Rashim Mannan, Archna Pruthi, Sanjana Mehrotra
Publikováno v: PLoS ONE, Vol 13, Iss 2, p e0192636 (2018)
MMP (Matrix metalloproteinase) 9 is reported to affect glaucoma pathogenesis by altering intraocular pressure (IOP) through its role in remodeling the extracellular matrix (ECM) in the trabecular meshwork. A genetic variant at the promoter region in
Externí odkaz: https://doaj.org/article/35ca4849212c47ed9a0a0b54e5fc90ae
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5
Neutrophils and Visceral Leishmaniasis: Impact on innate immune response and cross‐talks with macrophages and dendritic cells
Autor: Rajeev Kumar Pandey, Sanjana Mehrotra, Manu Kupani
Publikováno v: Journal of Cellular Physiology. 236:2255-2267
Neutrophils with their array of microbicidal activities are the first innate immune cells to guard against infection. They are also most crucial for the host's initial defense against Leishmania parasites which cause clinically diverse diseases rangi
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee8eda48dadca26ac89023e498e6fb78
https://doi.org/10.1002/jcp.30029
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6
IL-10 and TGF-β Induced Arginase Expression Contributes to Deficient Nitric Oxide Response in Human Visceral Leishmaniasis
Autor: Smriti Sharma, Sanjana Mehrotra, Rajiv Kumar, Rajeev Kumar Pandey, Shyam Sundar, Manu Kupani
Publikováno v: Frontiers in Cellular and Infection Microbiology, Vol 10 (2021)
Frontiers in Cellular and Infection Microbiology
Nitric oxide (NO) is an anti-microbial effector of the innate immune system which plays major role in non-specific killing of various pathogens including protozoan parasites. However, due to subversion of the host’s immune processes by pathogens, s
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ecf3b8b7a1c359715adeb15d5527baa
https://www.frontiersin.org/articles/10.3389/fcimb.2020.614165/full
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7
Genetic association between CDKN2B/CDKN2B-AS1 gene polymorphisms with primary glaucoma in a North Indian cohort: an original study and an updated meta-analysis
Autor: Rashim Mannan, Archna Pruthi, Nanamika Thakur, Sanjana Mehrotra, Manu Kupani
Publikováno v: BMC Medical Genomics, Vol 14, Iss 1, Pp 1-20 (2021)
BMC Medical Genomics
Background Variants in CDKN2B/CDKN2B-AS1 have been reported to modulate glaucoma risk in several GWAS across different populations. CDKN2B/CDKN2A encodes tumor suppressor proteins p16INK4A/p15INK4B which influences cell proliferation/senescence in RG
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61877bf8264adaada19b648abb172e50
https://doi.org/10.1186/s12920-020-00855-1
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8
Genetic association of -1562C>T polymorphism in the MMP9 gene with primary glaucoma in a north Indian population
Autor: Rajeev Kumar Pandey, Archna Pruthi, Sanjana Mehrotra, Rashim Mannan, Nanamika Thakur, Manu Kupani
Publikováno v: PLoS ONE, Vol 13, Iss 2, p e0192636 (2018)
PLoS ONE
MMP (Matrix metalloproteinase) 9 is reported to affect glaucoma pathogenesis by altering intraocular pressure (IOP) through its role in remodeling the extracellular matrix (ECM) in the trabecular meshwork. A genetic variant at the promoter region in
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6589e434924987d5dc19bdaa3cd489a0
http://europepmc.org/articles/PMC5809065?pdf=render
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