Zobrazeno 1 - 10
of 262
pro vyhledávání: '"Mantsyzov A."'
Autor:
Ren, Feng, Ding, Xiao, Zheng, Min, Korzinkin, Mikhail, Cai, Xin, Zhu, Wei, Mantsyzov, Alexey, Aliper, Alex, Aladinskiy, Vladimir, Cao, Zhongying, Kong, Shanshan, Long, Xi, Liu, Bonnie Hei Man, Liu, Yingtao, Naumov, Vladimir, Shneyderman, Anastasia, Ozerov, Ivan V., Wang, Ju, Pun, Frank W., Aspuru-Guzik, Alan, Levitt, Michael, Zhavoronkov, Alex
The AlphaFold computer program predicted protein structures for the whole human genome, which has been considered as a remarkable breakthrough both in artificial intelligence (AI) application and structural biology. Despite the varying confidence lev
Externí odkaz:
http://arxiv.org/abs/2201.09647
Autor:
Igor B. Levshin, Alexander Yu. Simonov, Alexey A. Panov, Natalia E. Grammatikova, Alexander I. Alexandrov, Eslam S. M. O. Ghazy, Vasiliy A. Ivlev, Michael O. Agaphonov, Alexey B. Mantsyzov, Vladimir I. Polshakov
Publikováno v:
Pharmaceuticals, Vol 17, Iss 6, p 723 (2024)
A series of hybrid compounds with triazole and thiazolidine nuclei connected by a linker has been synthesized and extensively studied. Various synthetic methods for the target compounds have been tested. A microbiological assessment of the obtained c
Externí odkaz:
https://doaj.org/article/13483073eed24242ad00227215e7d07b
It is shown that inhomogeneous broadening of the spectral line of active impurities may sustain simultaneously parity (P) and time (T) symmetries of a medium, in a finite range of field frequencies, what is forbidden by the causality principle in med
Externí odkaz:
http://arxiv.org/abs/1811.07324
Akademický článek
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Autor:
Nikita M. Shepelev, Sofia S. Mariasina, Alexey B. Mantsyzov, Alexander N. Malyavko, Sergey V. Efimov, Olga A. Petrova, Elena V. Rodina, Maria I. Zvereva, Olga A. Dontsova, Vladimir I. Polshakov
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-17 (2020)
Abstract Telomerase is a ribonucleoprotein enzyme, which maintains genome integrity in eukaryotes and ensures continuous cellular proliferation. Telomerase holoenzyme from the thermotolerant yeast Hansenula polymorpha, in addition to the catalytic su
Externí odkaz:
https://doaj.org/article/c30a64ef786b423ca96996243d680aa3
Autor:
Bushuev, V. A.1 (AUTHOR) vabushuev@yandex.ru, Mantsyzov, B. I.1 (AUTHOR) bmantsyzov@gmail.com
Publikováno v:
Journal of Experimental & Theoretical Physics. Sep2022, Vol. 135 Issue 3, p277-284. 8p.
Autor:
Feng Ren, Xiao Ding, Min Zheng, Mikhail Korzinkin, Xin Cai, Wei Zhu, Alexey Mantsyzov, Alex Aliper, Vladimir Aladinskiy, Zhongying Cao, Shanshan Kong, Xi Long, Bonnie Hei Man Liu, Yingtao Liu, Vladimir Naumov, Anastasia Shneyderman, Ivan V. Ozerov, Ju Wang, Frank W. Pun, Daniil A. Polykovskiy, Chong Sun, Michael Levitt, Alán Aspuru-Guzik, Alex Zhavoronkov
Publikováno v:
Chemical Science. 14:1443-1452
A novel CDK20 small molecule inhibitor discovered by artificial intelligence based on an AlphaFold-predicted structure demonstrates the first application of AlphaFold in hit identification for efficient drug discovery.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::00e0a412f03d6d3d3a3e69765bccbb88
https://doi.org/10.1039/d2sc05709c
https://doi.org/10.1039/d2sc05709c
Autor:
V. A. Bushuev, B. I. Mantsyzov
Publikováno v:
Journal of Experimental and Theoretical Physics. 135:277-284
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6ffbb687fca354424ceb913ba57b8f5b
https://doi.org/10.1134/s1063776122090138
https://doi.org/10.1134/s1063776122090138
Akademický článek
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Autor:
Alexey B. Mantsyzov, Oleg Y. Savelyev, Polina M. Ivantcova, Stefan Bräse, Konstantin V. Kudryavtsev, Vladimir I. Polshakov
Publikováno v:
Frontiers in Chemistry, Vol 6 (2018)
Synthetic β-peptides are potential functional mimetics of native α-proteins. A recently developed, novel, synthetic approach provides an effective route to the broad group of β-proline oligomers with alternating patterns of stereogenic centers. Co
Externí odkaz:
https://doaj.org/article/d872ab658dee42c6815dcaaa041923a8