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Peptide dendrimers as 'lead compounds' for the treatment of chronic lung infections by Pseudomonas aeruginosa in cystic fibrosis patients: in vitro and in vivo studies

Autor: Pompilio, Arianna, Geminiani, Cristina, Mantini, Paolo, Siriwardena, Thissa N., Di Bonaventura, Ivan, Reymond, Jean Louis, Di Bonaventura, Giovanni

Publikováno v: Infection and Drug Resistance
Pompilio, Arianna; Geminiani, Cristina; Mantini, Paolo; Siriwardena, Thissa N.; Di Bonaventura, Ivan; Reymond, Jean Louis; Di Bonaventura, Giovanni (2018). Peptide dendrimers as “lead compounds” for the treatment of chronic lung infections by Pseudomonas aeruginosa in cystic fibrosis patients: in vitro and in vivo studies. Infection and drug resistance, 11, pp. 1767-1782. Dove Medical Press 10.2147/IDR.S168868

Aim: In the present work, the potential of the D-enantiomeric dendrimers dG3KL and dTNS18 was evaluated in relation to tobramycin (Tob), for the development of novel antibacterials to treat Pseudomonas aeruginosa chronic lung infections in patients w

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c187d66f08ba4c06c62854d9fe95619
http://europepmc.org/articles/PMC6188189