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pro vyhledávání: '"Mantas Matjusaitis"'
Autor:
Mantas Matjusaitis, Laura J. Wagstaff, Andrea Martella, Bart Baranowski, Carla Blin, Sabine Gogolok, Anna Williams, Steven M. Pollard
Publikováno v:
Stem Cell Reports, Vol 13, Iss 6, Pp 1053-1067 (2019)
Summary: Cell lineage reprogramming via transgene overexpression of key master regulatory transcription factors has been well documented. However, the poor efficiency and lack of fidelity of this approach is problematic. Synthetic transcription facto
Externí odkaz:
https://doaj.org/article/edd7f09b05334865b6af465955dabac8
Autor:
Laura J. Wagstaff, Mantas Matjusaitis, Sabine Gogolok, Steven M. Pollard, Bart Baranowski, Andrea Martella, Carla Blin, Anna Williams
Publikováno v:
Matjusaitis, M, Wagstaff, L J, Martella, A, Baranowski, B, Blin, C, Gogolok, S, Williams, A & Pollard, S M 2019, ' Reprogramming of Fibroblasts to Oligodendrocyte Progenitor-like Cells Using CRISPR/Cas9-Based Synthetic Transcription Factors ', Stem Cell Reports . https://doi.org/10.1016/j.stemcr.2019.10.010
Stem Cell Reports
Stem Cell Reports, Vol 13, Iss 6, Pp 1053-1067 (2019)
Stem Cell Reports
Stem Cell Reports, Vol 13, Iss 6, Pp 1053-1067 (2019)
Summary Cell lineage reprogramming via transgene overexpression of key master regulatory transcription factors has been well documented. However, the poor efficiency and lack of fidelity of this approach is problematic. Synthetic transcription factor
Ability to functionally screen gene regulatory sequences, such as promoters and enhancers, in high throughput manner is an important prerequisite for many basic and translational research programs. One of the methods that allow such screening is STAR
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b7517023e51c2846c93c1ea9062f3dc8
https://doi.org/10.1101/2020.06.24.169714
https://doi.org/10.1101/2020.06.24.169714
Publikováno v:
ACS synthetic biology. 6(7)
Mammalian plasmid expression vectors are critical reagents underpinning many facets of research across biology, biomedical research, and the biotechnology industry. Traditional cloning methods often require laborious manual design and assembly of pla