Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Mantana K. Norman"'
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 348:311-315
The change in frequency of cocaine self-administration as a function of the unit dose is widely assumed to represent a graded pharmacodynamic response. Alternatively, a pharmacological theory states that during maintained self-administration, a quant
Autor:
Mantana K. Norman, Michael R. Tabet, Brittney K. Fey, Andrew B. Norman, Vladimir L. Tsibulsky, Ronald W. Millard
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 338:724-728
Differences in the time to maximal effect (T(max)) of a series of dopamine receptor antagonists on the self-administration of cocaine are not consistent with their lipophilicity (octanol-water partition coefficients at pH 7.4) and expected rapid entr
Autor:
Mantana K. Norman, James B. Chambers, Andrew B. Norman, William R. Buesing, Valerie Thompson, Jack W. Lipton, J.U. Heiman, Stephen C. Benoit
Publikováno v:
Physiology & Behavior. 96:593-601
The current study sought to determine whether prenatal 3,4-methylenedioxy-N-methamphetamine (MDMA) exposure from E14-20 in the rat resulted in behavioral sequelae in adult offspring. Prenatal MDMA exposure results in increased dopaminergic fiber dens
Autor:
William J. Ball, Mantana K. Norman, William R. Buesing, Amadeo J. Pesce, Andrew B. Norman, Michael R. Tabet
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 320:145-153
The predominantly human sequence, high-affinity anticocaine monoclonal antibody (mAb) 2E2 was cleared slowly from mouse blood by a first-order process with an elimination t 1/2 of 8.1 days. Infused 2E2 also produced a dramatic dose-dependent increase
Autor:
Mantana K. Norman, Kevin T. Schlueter, Asad D. Dalia, Vladimir L. Tsibulsky, Andrew B. Norman, Michael R. Tabet
Publikováno v:
Brain Research. 797:29-34
Intermittent administration of cocaine produced a progressive increase in the stereotypy response of rats to a challenge dose of cocaine (7.5 mg/kg, i.p.). Continuous infusion of cocaine (80 mg/kg per day) via osmotic pumps for 7 days into the sensit
Publikováno v:
The FASEB Journal. 26
Competitive dopamine receptor antagonists accelerate psychomotor stimulant self-administration. According to pharmacological theory of competitive antagonism antagonists raise the equiactive agonist concentration. In the self-administration paradigm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5cbe36dcd1efeb6e2b138e852ad2c214
https://europepmc.org/articles/PMC3017394/
https://europepmc.org/articles/PMC3017394/
Autor:
Mantana K. Norman, Michael R. Tabet, Amadeo J. Pesce, Andrew B. Norman, Vladimir L. Tsibulsky
Publikováno v:
Synapse (New York, N.Y.). 65(5)
Competitive dopamine receptor antagonists increase the rate of cocaine self-administration. As the rate of self-administration at a particular unit dose is determined by the satiety threshold and the elimination half-life (t1/2) of cocaine, we invest
Autor:
Michael R. Tabet, Mantana K. Norman, Andrew B. Norman, Vladimir L. Tsibulsky, Brittney K. Fey, Ronald W. Millard
Publikováno v:
The FASEB Journal. 24
Autor:
William R. Buesing, William J. Ball, Vladimir L. Tsibulsky, Michael R. Tabet, Mantana K. Norman, Andrew B. Norman
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 328(3)
The predominantly human sequence anti-cocaine monoclonal antibody (mAb), 2E2, has high affinity and specificity for cocaine and antagonizes cocaine distribution to the brain in mice. To determine whether 2E2 can alter the self-administration of cocai