Zobrazeno 1 - 10
of 213
pro vyhledávání: '"Mansoureh Eghbali"'
Autor:
Pietro Presicce, Monica Cappelletti, Marco Morselli, Feiyang Ma, Paranthaman Senthamaraikannan, Giulia Protti, Brian B. Nadel, Laila Aryan, Mansoureh Eghbali, Lukasz Salwinski, Neema Pithia, Emily De Franco, Lisa A. Miller, Matteo Pellegrini, Alan H. Jobe, Claire A. Chougnet, Suhas G. Kallapur
Publikováno v:
iScience, Vol 26, Iss 11, Pp 108118- (2023)
Summary: Intrauterine infection/inflammation (IUI) is a frequent complication of pregnancy leading to preterm labor and fetal inflammation. How inflammation is modulated at the maternal-fetal interface is unresolved. We compared transcriptomics of am
Externí odkaz:
https://doaj.org/article/77d0fd7b7d1341148a8871c73ddb3327
Publikováno v:
Cells, Vol 12, Iss 24, p 2794 (2023)
Gene expression is under tight regulation from the chromatin structure that regulates gene accessibility by the transcription machinery to protein degradation. At the transcript level, this regulation falls on RNA-binding proteins (RBPs). RBPs are a
Externí odkaz:
https://doaj.org/article/d773b063ec834b8a8e60aea720a8befc
Autor:
Lejla Medzikovic, Laila Aryan, Grégoire Ruffenach, Min Li, Nicoletta Savalli, Wasila Sun, Shervin Sarji, Jason Hong, Salil Sharma, Riccardo Olcese, Gregory Fishbein, Mansoureh Eghbali
Publikováno v:
JCI Insight, Vol 8, Iss 9 (2023)
Myocardial fibrosis and calcification associate with adverse outcomes in nonischemic heart failure. Cardiac fibroblasts (CF) transition into myofibroblasts (MF) and osteogenic fibroblasts (OF) to promote myocardial fibrosis and calcification. However
Externí odkaz:
https://doaj.org/article/b829dd6ae85a457db5a52c49922ce50b
Autor:
Louis Saddic, Sean Escopete, Lior Zilberberg, Shannon Kalsow, Divya Gupta, Mansoureh Eghbali, Sarah Parker
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 17, p 13571 (2023)
Marfan syndrome causes a hereditary form of thoracic aortic aneurysms with worse outcomes in male compared to female patients. In this study, we examine the effects of 17 β-estradiol on aortic dilation and rupture in a Marfan mouse model. Marfan mal
Externí odkaz:
https://doaj.org/article/31e5af9884e94dfdad34f253ef0e38b6
Autor:
Lejla Medzikovic, Tara Azem, Wasila Sun, Parmis Rejali, Leana Esdin, Shadie Rahman, Ateyeh Dehghanitafti, Laila Aryan, Mansoureh Eghbali
Publikováno v:
Cells, Vol 12, Iss 16, p 2077 (2023)
Mortality from myocardial infarction (MI) has declined over recent decades, which could be attributed in large part to improved treatment methods. Early reperfusion is the cornerstone of current MI treatment. However, reoxygenation via restored blood
Externí odkaz:
https://doaj.org/article/742377b5b0fc439cbdbf4cd4d22d2664
Publikováno v:
Respiratory Research, Vol 22, Iss 1, Pp 1-5 (2021)
Abstract We identified a novel microRNA biomarker panel consisting of 6 microRNAs predicting mortality in pediatric acute respiratory distress syndrome patients. Each of the identified mRNA have potential mechanistic importance in acute respiratory d
Externí odkaz:
https://doaj.org/article/f23321fc129146d9bc58b716d455451b
Autor:
Caitlin Sherman, Natalie Koons, Michael Zargari, Catherine Cha, Jason Hirsch, Richard Hong, Mansoureh Eghbali, Soban Umar
Publikováno v:
Frontiers in Medicine, Vol 9 (2022)
BackgroundFemales routinely receive bupivacaine for obstetric and regional anesthesia. An accidental overdose of bupivacaine can result in cardiotoxicity and cardiac arrest. Intralipid (ILP) rescues bupivacaine-induced cardiotoxicity in male rats. Ho
Externí odkaz:
https://doaj.org/article/7674135d779242c28b44aac1c6054fa0
Publikováno v:
Respiratory Research, Vol 21, Iss 1, Pp 1-14 (2020)
Abstract Pulmonary hypertension (PH) developing secondarily in pulmonary fibrosis (PF) patients (PF-PH) is a frequent co-morbidity. The high prevalence of PH in PF patients is very concerning since the presence of PH is a strong predictor of mortalit
Externí odkaz:
https://doaj.org/article/05a8cd02924c430799af1b7153de6c87
Publikováno v:
Biology of Sex Differences, Vol 11, Iss 1, Pp 1-17 (2020)
Abstract Many crucial cardiovascular adaptations occur in the body during pregnancy to ensure successful gestation. Maladaptation of the cardiovascular system during pregnancy can lead to complications that promote cardiac dysfunction and may lead to
Externí odkaz:
https://doaj.org/article/ec46672ccf804df2aeb451db6f0d665f
Autor:
Sara Duhachek‐Muggy, Kruttika Bhat, Paul Medina, Fei Cheng, Ling He, Claudia Alli, Mohammad Saki, Sree Deepthi Muthukrishnan, Gregoire Ruffenach, Mansoureh Eghbali, Erina Vlashi, Frank Pajonk
Publikováno v:
Stem Cells Translational Medicine, Vol 9, Iss 1, Pp 106-119 (2020)
Abstract The objective of the study was to identify the mechanism of action for a radiation mitigator of the gastrointestinal (GI) acute radiation syndrome (ARS), identified in an unbiased high‐throughput screen. We used mice irradiated with a leth
Externí odkaz:
https://doaj.org/article/91a88a70c1ea425785506c378e541c3e