Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Mansour Djedaini"'
Autor:
Robert Hariri, Shuyang He, William van der Touw, Kathy Karasiewicz, Natalia Ruggeri Barbaro, Theodore Drashansky, Kristina Tess, Mansour Djedaini
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 12, Iss 4 (2024)
Background Chimeric antigen receptor (CAR)-T cell quality and stemness are associated with responsiveness, durability, and memory formation, which benefit clinical responses. Autologous T cell starting material across patients with cancer is variable
Externí odkaz:
https://doaj.org/article/a5e3d83d570f46039b719e400523ec7d
Autor:
Maria Feola, Andrea Zamperone, Daniel Moskop, Huiyong Chen, Carla Casu, Dechen Lama, Julie Di Martino, Mansour Djedaini, Luena Papa, Marc Ruiz Martinez, Tenzin Choesang, Jose Javier Bravo-Cordero, Matthew MacKay, Paul Zumbo, Nathan Brinkman, Charles S. Abrams, Stefano Rivella, Shilpa Hattangadi, Christopher E. Mason, Ronald Hoffman, Peng Ji, Antonia Follenzi, Yelena Z. Ginzburg
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-14 (2021)
Maria Feola et al., elucidate the compensatory role of pleckstrin-2 in ineffective erythropoiesis in β-thalassemic mice by reducing cofilin-mediated apoptosis and enhancing enucleation by activating RacGTPases. These findings could support future th
Externí odkaz:
https://doaj.org/article/e6bba204b45a41b58086958c1edd4975
Publikováno v:
Stem Cells Translational Medicine, Vol 9, Iss 4, Pp 531-542 (2020)
Abstract Attempts to expand ex vivo the numbers of human hematopoietic stem cells (HSCs) without compromising their marrow repopulating capacity and their ability to establish multilineage hematopoiesis has been the subject of intense investigation.
Externí odkaz:
https://doaj.org/article/6d6992c2a7b74404b3b2ef5cabb9be85
Autor:
Luena Papa, Mansour Djedaini, Tiphaine C. Martin, Mahtab Zangui, Kristin G. Beaumont, Robert Sebra, Ramon Parsons, Christoph Schaniel, Ronald Hoffman
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 8 (2020)
Ex vivo expansion strategies of human hematopoietic stem cell (HSC) grafts with suboptimal stem cell dose have emerged as promising strategies for improving outcomes of HSC transplantation in patients with hematological malignancies. While exposure o
Externí odkaz:
https://doaj.org/article/81e1d7290d9e49df8cb28b6a6ed70a9b
Publikováno v:
Stem Cells International, Vol 2019 (2019)
Quiescent and self-renewing hematopoietic stem cells (HSCs) rely on glycolysis rather than on mitochondrial oxidative phosphorylation (OxPHOS) for energy production. HSC reliance on glycolysis is considered an adaptation to the hypoxic environment of
Externí odkaz:
https://doaj.org/article/13cfc7f6ea724169856c6aebaec5b981
Autor:
Jérôme Gilleron, Gwennaëlle Bouget, Stoyan Ivanov, Cindy Meziat, Franck Ceppo, Bastien Vergoni, Mansour Djedaini, Antoine Soprani, Karine Dumas, Arnaud Jacquel, Laurent Yvan-Charvet, Nicolas Venteclef, Jean-François Tanti, Mireille Cormont
Publikováno v:
Cell Reports, Vol 25, Iss 12, Pp 3329-3341.e5 (2018)
Summary: Obesity modifies T cell populations in adipose tissue, thereby contributing to adipose tissue inflammation and insulin resistance. Here, we show that Rab4b, a small GTPase governing endocytic trafficking, is pivotal in T cells for the develo
Externí odkaz:
https://doaj.org/article/c2d16480a4704158978b3fd9e7d8c0ad
Autor:
Didier F. Pisani, Rayane A. Ghandour, Guillaume E. Beranger, Pauline Le Faouder, Jean-Claude Chambard, Maude Giroud, Alexandros Vegiopoulos, Mansour Djedaini, Justine Bertrand-Michel, Michel Tauc, Stephan Herzig, Dominique Langin, Gérard Ailhaud, Christophe Duranton, Ez-Zoubir Amri
Publikováno v:
Molecular Metabolism, Vol 3, Iss 9, Pp 834-847 (2014)
Objective: Brite adipocytes are inducible energy-dissipating cells expressing UCP1 which appear within white adipose tissue of healthy adult individuals. Recruitment of these cells represents a potential strategy to fight obesity and associated disea
Externí odkaz:
https://doaj.org/article/8e7e771460fd48bc8cd10208eb53c7ce
Autor:
Luena Papa, Tiphaine C. Martin, Mansour Djedaini, Mahtab Zangui, Umut Ozbek, Ramon Parsons, Ronald Hoffman, Christoph Schaniel
Publikováno v:
Experimental Hematology. 122:41-54
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ef67a2a7bfca2c2d8e0d32022166f251
https://doi.org/10.1016/j.exphem.2023.03.006
https://doi.org/10.1016/j.exphem.2023.03.006
Autor:
Ronald Hoffman, Manisha Kintali, Christoph Schaniel, Camelia Iancu-Rubin, Luena Papa, Mansour Djedaini, Marcia Meseck, Mahtab Zangui
Publikováno v:
Cytotherapy. 23:841-851
Background aims Allogeneic hematopoietic stem cell transplantation (allo-HSCT) is a potentially curative therapy for a wide range of malignant and genetic disorders of the hematopoietic and immune systems. Umbilical cord blood (UCB) is a readily avai
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d19146767c8658dc799b0e7b43263077
https://doi.org/10.1016/j.jcyt.2021.04.001
https://doi.org/10.1016/j.jcyt.2021.04.001
Publikováno v:
Stem Cells Translational Medicine, Vol 9, Iss 4, Pp 531-542 (2020)
Stem Cells Translational Medicine
Stem Cells Translational Medicine
Attempts to expand ex vivo the numbers of human hematopoietic stem cells (HSCs) without compromising their marrow repopulating capacity and their ability to establish multilineage hematopoiesis has been the subject of intense investigation. Although
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd51cfcc21f70f881a3257ec71a57bc1
https://doaj.org/article/6d6992c2a7b74404b3b2ef5cabb9be85
https://doaj.org/article/6d6992c2a7b74404b3b2ef5cabb9be85